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Ueda, Mitsutoshi,Maruyama, Toshio The Korean Ceramic Society 2012 한국세라믹학회지 Vol.49 No.1
Mass transport near grain boundary in a magnetite bi-crystal has been estimated at 823 K by finite element method. Mass transport near grain boundary strongly depends on the diffusivities along grain boundary. If grain boundary diffusion has the same oxygen activity dependence as lattice diffusion, there is no mass transport between grains and grain boundary. On the other hand, mass transport between grains and grain boundary is observed in the case that grain boundary diffusion has different oxygen activity dependence.
Adsorption and Reaction of CO and NO on Ir(111) Under Near Ambient Pressure Conditions
Ueda, K.,Suzuki, K.,Toyoshima, R.,Monya, Y.,Yoshida, M.,Isegawa, K.,Amemiya, K.,Mase, K.,Mun, B. S.,Arman, M. A. Springer Science + Business Media 2016 Topics in catalysis Vol.59 No.5
<P>The adsorption and reaction of CO and NO on Ir(111) have been studied by near-ambient pressure X-ray photoelectron spectroscopy (NAP-XPS) together with low-energy electron diffraction, scanning tunneling microscopy, and mass spectroscopy (MS). Under both ultrahigh vacuum (UHV) and NAP conditions CO molecules occupy on-top sites of the Ir(111) surface at room temperature (RT) by forming two-dimensional clusters. Exposure to NO under UHV conditions at RT induces partially dissociative adsorption, while NAP NO exposure leads to a Ir(111) surface that is covered by molecular NO. We conducted in-operando NAP-XPS/MS observation of the NO + (CO)-C-13 reaction under a NAP condition as a function of temperature. Below 210 degrees C adsorption of NO is inhibited by CO, while above 210 degrees C the CO inhibition is released due to partial desorption of CO and dissociative adsorption of NO starts to occur leading to associative formation of N-2. Under the most active condition studied here the Ir surface is covered by a dense co-adsorption layer consisting of on-top CO, atomic N and O, which suggests that this reaction is not a NO-dissociation-limited process but a N-2/CO2 formation-limited process.</P>
Control and Mechanism of Tumor Promotion in UV-Carcinogenesis
Ueda, Masato,Budiyanto, Arief,Ashida, Masashi,Bito, Toshinori,Ichihashi, Masamitsu Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Carcinogenesis can be theoretically divided to intiation step and promotion step. Intiation associates with genetic alterations including p53 tumor suppressor gene and ras oncogene. Promotion involves in clonal expansion of of an initiated cell by epigenetic mechanism, mainly through signal transduction and gene expression. Ultraviolet light (UV) acts as both initiator and promoter. Initiation is closely related with DNA damage induced by UV, including cyclobutane pyrimidine dimers, (6-4) photoproducts and 8-hydroxy-2'-deoxyguanosine. Cyclobutane pyrimidine dimers and (6-4) photoproducts are directly induced by UV, while 8-hydroxy-2'-deoxyguanosine is induced indirectly by the reactive oxygen species. Because initiation is an irreversal genetic event, while promotion is a reversal and epigenetic event, to know the molecular mechanisms of tumor promotion in UV-carcinogenesis is crucial to develop preventive medicine and suppress UV-carcinogenesis. Because ROS is also involved in signal transduction of the cell, anti-oxidant could be the good candidate of anti-promoting agent. Here, we describe the suppressive effect of UV-carcinogenesis by various anti-oxidant including olive oil. In addition, we discuss about the mechanism of UVB-induced expression of cyclooxygenase-2, which might be a representative molecule involved in promotion of UV-carcinogenesis.
Evaluation of 131I (monoiodide) BSP for Clinical Studies
Ueda, Hideo,Iro, Masahiro,Kurata, Kunio,Yamada, Hideo,Iwase, Tohru,Migita, Tohru,Kameda, Haruo,Kato, Sadatake,Sato, Noboru,Ide, Kazuko,Wakebayashi, Takao 대한핵의학회 1971 핵의학 분자영상 Vol.5 No.1
"In 1925 Rosenthal and White introduced a bromosulfophthalein (BSP) dye retention test as a sensitive indicator of liver function. Even now it is regared as one of the most sensitive agents for the detection of non-icteric liver disease (liver cirrhosis, early stage of acute-hepatitis and hepatic tumor). BSP accumulates in the liver cells, conjugates with glutathione and is excreted into the bile. Therefore, a disorder in its excretion is due to a disturbance of one of these processes. Since bilirubin and BSP compete for uptake by the liver and increased serum bilirubin interferes with the colorimetric determination of BSP, it has been considered that BSP test is inappropriate for the differential diagnosis of jaundice conditions. It has been generally said that when jaundice is present, the BSP test is useless and should not be performed. In 1955, Taplin et al. labeled rose bengal, a dye similarly metabolized in the liver as BSP, with 131I and measured the hepatic excretion of this dye by external monitoring. Laster, Blahd et al. applied this method to the determination of the peripheral pool, succeeding in the diagnosis of chronic and subacute hepatic diseases without colorimetry. In 1968, Yamada, Taplin et al. suggested the possibility of differentiating so-called medical jaundice from surgical jaundice by scanning the subjects during 24 to 48 hours following intravenous injection of 131I-labeled rose bengal. As mentioned before, many authorities hold the opinion that BSP is not proper for the differential diagnosis of jaundice states. Some have tried to diagnose biliary tract obstruction by a malignant tumor by measuring BSP excretion into duodenal fluid and others by quantitating changes in serum levels of conjugated and free BSP. Furthermore, Burton et al. reported that in patients with extrahepatic obstructive jaundice, BSP retention was observed for 24 days after its administration. From a consideration of all these finding we came to a conclusion that the differential diagnosis of various jaundice states, (medical, surgical and constitutional) is possible by sequential scanning with radioisotope-labeled BSP, as with rose bengal, in accordance with procedures described by Yamada, Taplin et al. The evidence suggested that labeled BSP might make a more important contribution than rose bengal. "
Ueda, Tetsuhiko,Takase, Shouhei,Ikeda, Tadashige,Iwahori, Yutaka The Korean Society for Composite Materials 2008 Advanced composite materials Vol.17 No.2
As the first step in discussing the reliability of composite structures, a fundamental study was performed to obtain the scattering characteristics of glass-fiber reinforced plastics (GFRP) and woven carbon fiber reinforced plastics (WCFRP) as well as a reference metal. The Euler buckling load was obtained experimentally for each material. The experiments were conducted for specified rectangular specimens with simply supported edges. A new attachment to realize the simply support boundary conditions for composite materials have been prepared before these experiments. The scattering data in the results for GFRP and WCFRP composites were compared with those of a typical metal of aluminum alloy. The experimental data were also compared with numerical simulations including the uncertainties.
Ueda Cristina Emiko,Duarte Paulo Schiavom,Castroneves Luciana Audi,Coura-Filho George Barbério,Sado Heitor Naoki,Sapienza Marcelo Tatit,Ana Oliveira Hoff,Buchpiguel Carlos Alberto 대한핵의학회 2020 핵의학 분자영상 Vol.54 No.6
Purpose To compare the 18F-NaF PET/CT studies (18F-NaF) with other imaging methods in the detection of skeletal metastases (SM) in patients with medullary thyroid cancer (MTC). Methods We retrospectively analyzed 31 patients with MTC who performed 18F-NaF to assess SM. The results of the 18F-NaF were compared with other imaging methods performed for metastasis detection: 99Tc-MDP bone scan (BS), magnetic resonance imaging (MRI), contrast-enhanced CT (CT), and 68Ga-Dotatate and 18F-FDG PET/CT studies. A qualitative analysis comparing the 18F-NaF findings with the ones of the other methods was performed, and the results were classified as superior (>), equal (=), and inferior (<). Results Eleven patients had no bone metastases detected on any of the imaging methods used. Twenty patients presented SM depicted on 18F-NaF. Of these 20 patients, 12 performed bone scan (in 9 18F-NaF > BS and in 3 18F-NaF = BS), 1 performed 18F-FDG (18F-NaF > 18F-FDG), 4 performed 68Ga-Dotatate (in 2 18F-NaF > 68Ga-Dotatate and in 2 18F-NaF = 68Ga-Dotatate), 20 performed CT of at least one body segment (in 15 18F-NaF = CT and in 5 18F-NaF > CT), and 16 performed MRI of at least one body segment, and in all of them, the 18F-NaF was equal to the MRI. Beside this, the 18F-NaF detected SMin body segments not routinely scanned in MRI and CT. Conclusion In patients with MTC, the 18F-NaF seems to be equal or superior to other imaging modalities in the detection of SM and allows the analysis of the whole skeletal in a single study.