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- 저자 : Tricia Nemoseck (검색결과 2 건)
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Shirin Hooshmand,Brittany Holloway,Tricia Nemoseck,Sarah Cole,Yumi Petrisko,Mee Young Hong,Mark Kern 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.9
Agave nectar is a fructose-rich liquid sweetener derived from a plant, and is often promoted as a low glycemic alternative to refined sugar. However, little scientific research has been conducted in animals or humans to determine its metabolic and/or health effects. The aim of this study was to explore the influence of agave nectar versus sucrose on weight gain, adiposity, fasting plasma blood glucose, insulin, and lipid levels. Eighteen (n = 18) male ICR mice (33.8 – 1.6 g) were divided into two groups (n = 6 for agave nectar and n = 12 for sucrose) and provided free access to one of two diets of equal energy densities differing only in a portion of the carbohydrate provided. Diets contained 20% carbohydrate (by weight of total diet) from either raw agave nectar or sucrose. Epididymal fat pads were excised, and blood was collected after 34 days. Weight gain (4.3 – 2.2 vs. 8.4 – 3.4 g), fat pad weights (0.95 – 0.54 vs. 1.75 – 0.66 g), plasma glucose (77.8 – 12.2 vs. 111.0 – 27.9 mg/dL), and insulin (0.61 – 0.29 vs. 1.46 – 0.81 ng/mL) were significantly lower (P £ .05) for agave nectar-fed mice compared to sucrose-fed mice respectively. No statistically significant differences in total cholesterol or triglycerides were detected. These results suggest that in comparison to sucrose, agave nectar may have a positive influence on weight gain and glucose control. However, more research with a larger sample of animals and/or with human subjects is warranted.
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Julie Bornhoeft,Debra Castaneda,Tricia Nemoseck,Piwen Wang,Susanne M. Henning,Mee Young Hong 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.8
Acute and chronic inflammation and dyslipidemia play a critical role in the development of various diseases,including cardiovascular disease. Green tea polyphenols possess potent antioxidative and anti-inflammatory properties that contribute to the beneficial effects on heart health. The present study was carried out to determine if administration of a green tea extract (Polyphenon E [PPE]; Mitsui Norin Co., Ltd., Tokyo, Japan) at 0.2% in the diet reduces cardiovascular risk factors, including dyslipidemia, inflammation, adiposity, and oxidative stress, in rats fed an atherogenic (high fat, cholesterol,and sugar) diet with dextran sodium sulfate (DSS) in drinking water. DSS treatment increased serum total cholesterol, lowdensity lipoprotein (LDL)-cholesterol, C-reactive proteins (CRP), and markers of liver toxicity and decreased high-density lipoprotein (HDL)-cholesterol significantly. Adding PPE to the atherogenic diet (PPE-diet) was associated with lower total cholesterol and LDL-cholesterol (P < .001) and increased HDL-cholesterol (P = .001). In addition, the PPE-diet was associated with decreased serum CRP concentration (P = .023) and increased total antioxidant capacity (P = .016) and catalase (P = .001)and glutathione peroxidase (P = .050) activities. The PPE-diet significantly lowered epididymal fat pad weight (P = .009). Feeding the PPE-diet also ameliorated some of the DSS-induced lipid, inflammatory, and oxidative symptoms. In summary,green tea supplementation decreased several cardiovascular risk factors, including body composition, dyslipidemia, inflammatory status, and antioxidant capacity, in rats fed an atherogenic diet. This study supports green tea as an effective dietary component for sustaining cardiovascular health.
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