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Masahiro Sekimoto,Sadao Kawamura,Tomoya Ishitsubo,ShinsukeAkizuki,Masayuki Mizuno 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
This paper aims at generating desired feedforward torque for a specified motion by reuse of time-series to rque data acquired by the iterative learning control. The suggested method named motion-scalet rans for mation realizes a motion to an arbitrarily specified posture of a two-DOF planar robot arm on the basis of arithmetical operations of time-series to rque of only four motions. The algorism is theoretically presented, and the effectiveness is confirmed in experiments. It is shown by the experimental results that the trajectory tracking error so fangular velocities by the motion-scalet rans formationt end to be smaller than those by the computed to rque method.
Minoru Kobayashi,Toshitaka Uematsu,Gaku Nakamura,Hidetoshi Kokubun,Tomoya Mizuno,Hironori Betsunoh,Takao Kamai 대한감염학회 2018 Infection and Chemotherapy Vol.50 No.3
Background Diabetes is considered a risk factor for acquisition of febrile urinary tract infection (f-UTI), but information on the association of diabetes with subsequent course of the disease is lacking. Thus, we investigated the clinical variables including diabetic status which determined the clinical course in patients with community-acquired f-UTI. Materials and Methods Patients hospitalized consecutively for f-UTI between February 2016 and January 2018 were used for this single center study. The routine laboratory tests including blood glucose and glycated hemoglobin (HbA1c) were done and empiric treatment with parenteral antibiotics was commenced on admission. The clinical course such as duration of fever (DOF) and length of hospital stay (LOS) were compared among groups classified by the clinical variables. Results Among the101 patients admitted for f-UTI, 15 patients with diabetes (14.9%) experienced significantly longer febrile period and hospitalization compared to those with hyperglycemia (n = 18, 17.8%) or those without diabetes and hyperglycemia (n = 68, 67.3%). Of the laboratory parameters tested on admission and several clinical factors, the presence of diabetes and risk factors for severe complicated infection (hydronephrosis, urosepsis, and disseminated intravascular coagulopathy) as well as HbA1c and albumin were identified as predictors for LOS by univariate analysis, whereas none of the variables failed to predict DOF. In the subsequent multivariate analysis, HbA1c levels and albumin levels were isolated as independent predictors of LOS. Conclusion Patients with higher HbA1c and lower albumin levels required the longest period of hospitalization. Thus, an evaluation of diabetic and nutritional status on admission will be feasible to foretell the clinical course and better manage the subset of patients at risk of prolonged hospitalization.
Chemical variation in molecular cloud cores in the Orion A cloud. II.
Tatematsu, Ken'ichi,Ohashi, Satoshi,Umemoto, Tomofumi,Lee, Jeong-Eun,Hirota, Tomoya,Yamamoto, Satoshi,Choi, Minho,Kandori, Ryo,Mizuno, Norikazu Astronomical Society of Japan 2014 Publications of the Astronomical Society of Japan Vol.66 No.1
Tamaki Tanaka,Kazuhiro Takehara,Natsumi Yamashita,Mika Okazawa-Sakai,Kazuya Kuraoka,Norihiro Teramoto,Kenichi Taguchi,Katsushige Yamashiro,Hidenori Kato,Tomoya Mizunoe,Rie Suzuki,Dan Yamamoto,Arisa Ue 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.5
Objective: To clarify the frequency of deficient mismatch repair (dMMR) in Japanese ovarian cancer patients, we examined microsatellite instability (MSI) status and immunohistochemistry (IHC) subtypes, including endometrioid carcinoma (EMC), clear cell carcinoma (CCC), or a mixture of both (Mix). Methods: We registered 390 patients who were diagnosed with EMC/CCC/Mix between 2006 and 2015 and treated at seven participating facilities. For 339 patients confirmed eligible by the Central Pathological Review Board, MSI, IHC, and MutL homolog 1 methylation analyses were conducted. The tissues of patients with Lynch syndrome (LS)-related cancer histories, such as colorectal and endometrial cancer, were also investigated. Results: MSI-high (MSI-H) status was observed in 2/217 CCC (0.9%), 10/115 EMC (8.7%), and 1/4 Mix (25%). Additionally, loss of MMR protein expression (LoE-MMR) was observed in 5/219 (2.3%), 16/115 (14.0%), and 1/4 (25%) patients with CCC, EMC, and Mix, respectively. Both MSI-H and LoE-MMR were found significantly more often in EMC (p<0.001). The median (range) ages of patients with MMR expression and LoE-MMR were 54 (30–90) and 46 (22–76) (p=0.002), respectively. In the multivariate analysis, advanced stage and histological type were identified as prognostic factors. Conclusion: The dMMR rate for EMC/CCC was similar to that reported in Western countries. In Japan, it is assumed that the dMMR frequency is higher because of the increased proportion of CCC.