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        A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers

        Yanagi, Nobuaki,Kitamura, Hiroko,Mizuno, Mitsuhito,Hata, Koichi,Uchiyama, Tetsuro,Kuga, Hiroaki,Matsushita, Tetsuhiro,Kurosaki, Shizuka,Uehara, Masamichi,Ogami, Akira,Higashi, Toshiaki Occupational Safety and Health Research Institute 2014 Safety and health at work Vol.5 No.4

        Background: Focusing on the respiratory function for health effect indices, we conducted a cross-sectional study on workers who did and did not handle toner to compare the longitudinal changes. Methods: Among 116 individuals who worked for a Japanese business equipment manufacturer and participated in the study, the analysis included 69 male workers who we were able to follow up for 4 years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29 workers not engaged in these tasks as the referent group, and compared their respiratory function test results: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forced expiratory volume in 1 second ($FEV_1$), and forced expiratory volume in 1 second as a percent of forced vital capacity ($FEV_1%$). Results: The cross-sectional study of the respiratory function test results at the baseline and at the $5^{th}$ year showed no statistically significant differences in PEFR, VC, %VC, $FEV_1$, and $FEV_1%$ between the exposed and referent workers. Also, respiratory function time-course for 4 years was calculated and compared between the groups. No statistically significant differences were shown. Conclusion: Our study does not suggest any toner exposure effects on respiratory function. However, the number of subjects was small in our study; studies of larger populations will be desired in the future.

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        A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers

        Nobuaki Yanagi,Hiroko Kitamura,Mitsuhito Mizuno,Koichi Hata,Tetsuro Uchiyama,Hiroaki Kuga,Tetsuhiro Matsushita,Shizuka Kurosaki,Masamichi Uehara,,Akira Ogami,Toshiaki Higashi 한국산업안전보건공단 산업안전보건연구원 2014 Safety and health at work Vol.5 No.4

        Background: Focusing on the respiratory function for health effect indices, we conducted a crosssectionalstudy on workers who did and did not handle toner to compare the longitudinal changes. Methods: Among 116 individuals who worked for a Japanese business equipment manufacturer andparticipated in the study, the analysis included 69 male workers who we were able to follow up for 4years. We categorized the 40 workers engaged in toner-handling work as the exposed group and the 29workers not engaged in these tasks as the referent group, and compared their respiratory function testresults: peak expiratory flow rate (PEFR), vital capacity (VC), predicted vital capacity (%VC), forcedexpiratory volume in 1 second (FEV1), and forced expiratory volume in 1 second as a percent of forcedvital capacity (FEV1%). Results: The cross-sectional study of the respiratory function test results at the baseline and at the 5thyear showed no statistically significant differences in PEFR, VC, %VC, FEV1, and FEV1% between theexposed and referent workers. Also, respiratory function time-course for 4 years was calculated andcompared between the groups. No statistically significant differences were shown. Conclusion: Our study does not suggest any toner exposure effects on respiratory function. However, thenumber of subjects was small in our study; studies of larger populations will be desired in the future

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