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      • KCI등재

        The Gene Polymorphism of VMAT2 Is Associated with Risk of Schizophrenia in Male Han Chinese

        Hongying Han,Xiaowei Xia,Huirong Zheng,Chongbang Zhao,Yanming Xu,Jiong Tao,Xianglan Wang 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.11

        Objective To investigate the association between gene polymorphism of vesicular monoamine transporter type 2(VMAT2) and schizophrenia in Han Chinese population.Methods 430 patients with schizophrenia and 470 age-sex matched controls were recruited from four mental health centers. All patients were diagnosed by two psychiatrists based on the Structured Clinical Interview for DSM Disorders (SCID). The ligase detection reactions (LDR) method was used to assess the polymorphism of the two SNPs (rs363371 and rs363324) of VMAT2.Results No associations of two SNPs with schizophrenia was found. When we stratified males and females for the analysis, we found that that in the recessive model of rs363371, there was an obvious significant association between rs363371 and schizophrenia in males (OR=0.564, 95% CI=0.357–0.892, p=0.014) but not females. For the association between rs363324 and schizophrenia, no association was found in either males or females. No association was found when stratifying early-onset schizophrenia and late-onset schizophrenia.Conclusion Our findings indicate that both rs363371 and rs363324 were not associated with schizophrenia, while it seemed that the AA genotype of rs363371 plays a protective effect in male Chinese in developing schizophrenia.

      • SCISCIESCOPUS

        5G Converged Cell-Less Communications in Smart Cities

        Han, Tao,Ge, Xiaohu,Wang, Lijun,Kwak, Kyung Sup,Han, Yujie,Liu, Xiong Institute of Electrical and Electronics Engineers 2017 IEEE communications magazine Vol.55 No.3

        <P>Ubiquitous information service converged by different types of heterogeneous networks is one of fundamental functions for smart cities. Considering the deployment of 5G ultra-dense wireless networks, 5G converged cell-less communication networks are proposed to support mobile terminals in smart cities. To break obstacles of heterogeneous wireless networks, the 5G converged cell-less communication network is vertically converged in different tiers of heterogeneous wireless networks and horizontally converged in celled architectures of base stations/access points. Moreover, the software defined network controllers are configured to manage the traffic scheduling and resource allocation in 5G converged cell-less communication networks. Simulation results indicate the coverage probability and the energy saving at both base stations and mobile terminals are improved by the cooperative grouping scheme in 5G converged cell-less communication networks.</P>

      • Doping palladium with tellurium for the highly selective electrocatalytic reduction of aqueous CO <sub>2</sub> to CO

        Tao, Hengcong,Sun, Xiaofu,Back, Seoin,Han, Zishan,Zhu, Qinggong,Robertson, Alex ,W.,Ma, Tao,Fan, Qun,Han, Buxing,Jung, Yousung,Sun, Zhenyu Royal Society of Chemistry 2018 Chemical Science Vol.9 No.2

        <▼1><P>The doping of Pd with a small amount of Te can selectively convert CO<SUB>2</SUB> to CO with a low overpotential.</P></▼1><▼2><P>Designing highly selective and energy-efficient electrocatalysts to minimize the competitive hydrogen evolution reaction in the electrochemical reduction of aqueous CO<SUB>2</SUB> remains a challenge. In this study, we report that doping Pd with a small amount of Te could selectively convert CO<SUB>2</SUB> to CO with a low overpotential. The PdTe/few-layer graphene (FLG) catalyst with a Pd/Te molar ratio of 1 : 0.05 displayed a maximum CO faradaic efficiency of about 90% at –0.8 V (<I>vs.</I> a reversible hydrogen electrode, RHE), CO partial current density of 4.4 mA cm<SUP>–2</SUP>, and CO formation turnover frequency of 0.14 s<SUP>–1</SUP> at –1.0 V (<I>vs.</I> a RHE), which were 3.7-, 4.3-, and 10-fold higher than those of a Pd/FLG catalyst, respectively. Density functional calculations showed that Te adatoms preferentially bind at the terrace sites of Pd, thereby suppressing undesired hydrogen evolution, whereas CO<SUB>2</SUB> adsorption and activation occurred on the high index sites of Pd to produce CO.</P></▼2>

      • KCI등재

        Phenomenology of the Littlest Higgs Model

        Tao Han 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.2

        The little Higgs idea is a new way to solve the \little hierarchy" problem by protecting the Higgs mass from quadratically divergent one-loop corrections. I describe the phenomenology of one particular realization of the little Higgs idea: the \Littlest Higgs" model.

      • Targeting SHCBP1 Inhibits Cell Proliferation in Human Hepatocellular Carcinoma Cells

        Tao, Han-Chuan,Wang, Hai-Xiao,Dai, Min,Gu, Cheng-Yu,Wang, Qun,Han, Ze-Guang,Cai, Bing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

        Src homology 2 domain containing (SHC) is a proto-oncogene which mediates cell proliferation and carcinogenesis in human carcinomas. Here, the SHC SH2-domain binding protein 1 (SHCBP1) was first established to be up-regulated in human hepatocellular carcinoma (HCC) tissues by array-base comparative genome hybridization (aCGH). Meanwhile, we examine and verify it by quantitative real-time PCR and western blot. Our current data show that SHCBP1 was up-regulated in HCC tissues. Overexpression of SHCBP1 could significantly promote HCC cell proliferation, survival and colony formation in HCC cell lines. Furthermore, knockdown of SHCBP1 induced cell cycle delay and suppressed cell proliferation. Furthermore, SHCBP1 could regulate the expression of activate extracellular signal-regulated kinase 1/2 (ERK1/2) and cyclin D1. Together, our findings indicate that SHCBP1 may contribute to human hepatocellular carcinoma by promoting cell proliferation and may serve as a molecular target of cancer therapy.

      • KCI등재

        汉韩视觉感官词 “大” 和 “크다” 的词义投射

        韩松涛(Han Song tao) 동양한문학회 2015 동양한문학연구 Vol.42 No.-

        시각감각기관은 사람의 중요한 감각기관 중의 하나이며, 색채, 명암, 공간적 크기 등 다른 감각기관보다 더 풍부한 내용들을 받아들일 수 있다. 그리고 이렇게 받아들여진 내용들은 시각감각어를 통해 표현하게 된다. 중국어 ‘大’와 한국어 ‘크다’는 사람들의 넓은 공간의 인지를 나타내는 일종의 언어적 표현이다. 중국어 ‘大’와 한국어 ‘크다’는 시각감각어로, 사물의 면적이나 부피, 용량 등이 일반적 기준을 초과한다는 의미를 나타내며, 이는 사람들이 공간적 개념으로 사물을 인지한 것에 대한 결과이다. 중국어 ‘大’와 한국어 ‘크다’의 다의 구조에서 우리는 다음과 같은 사실을 발견할 수 있다. 각각이 공간적 개념의 근원 영역에서 출발하여 정도, 성질, 수량 등 다른 목표 영역으로 투사되는데 양자는 투사하는 방향은 비슷하지만 투사한 후 나타나는 의미는 완전히 대응되지 못한다는 것이다. 본고에서는 중국어 ‘大’와 한국어 ‘크다’가 의미를 투사하는 과정에서 나타나는 차이를 분석하고 각각의 인지적 특징에 대해 검토하도록 하겠다. Visual sense is one of the important senses of human beings, which offers us more abundant contents than any other senses. For instance, we can have access to colors, lights and space through visual sense and we can use visual sensory words to describe these contents. As a language presentation of human’s vast spatial perception, “大” in Chinese and “크다” in Korean is a good case in point. As a visual sensory word, “大” in Chinese and “크다” in Korean describes the size, volume or capacity of an object that exceeds normal standard. It is the result of human’s perception of an object in the concept of space. However, in the polysemy structure of “大” in Chinese and “크다” in Korean, we find both words describe the contents projecting from the source conceptual domain of the space to other target domains such as extent, property and quantity. We also realize that the projection direction of both words is almost the same, but the meanings after projection do not show one hundred percent equivalence. The paper aims to analyze the similarities and differences of both words in the course of projection and discuss their cognitive characteristics.

      • KCI등재

        汉韩空间形容词“长”和“길다”的认知域投射

        韩松涛(Han Song tao) 동양한문학회(구 부산한문학회) 2017 동양한문학연구 Vol.46 No.-

        사람의 여러 가지 인지 중에서 공간에 대한 인지는 가장 기본적이다. 사람은 공간의 크기, 길이, 높이, 면적 등의 내용들을 인지할 수 있으며 이렇게 인지한 내용들은 공간형용사를 통해 표현하게 된다. 이와 같이 특정한 어휘로 공간 특징을 나타내는 것은 모든 언어의 공통점이기도 하다. 인간은 공간을 1차원, 2차원 그리고 3차원으로 구분하고 다양한 공간형용사를 통해 다른 공간 차원의 특징을 표현한다. 한국어 ‘길다’와 중국어 ‘长’은 각각 1차원 공간에서 사물의 길이에 대해 인지한 언어 표현이다. 두 어휘의 의미 투사에 대한 분석을 통해 우리는 다음과 같은 사실을 발견할 수 있다. 두 어휘는 근원 영역에서 비슷한 의미를 나타낸다. 그리고 양자는 근원 영역에서 출발하여 은유를 통해 다른 목표 영역으로 투사되는데 투사하는 영역은 비슷하지만 투사한 후 나타나는 의미는 완전히 똑같지 않다는 것이다. 본 논문에서는 대조언어학과 인지언어학을 이론적 근거로 하여 한국어 ‘길다’와 중국어 ‘长’이 의미를 투사하는 과정에서 나타내는 차이를 분석하고 각각의 인지영역 투사 특징에 대해 논의하도록 한다. The most fundamental sense in human beings’ cognition is the sense of space. We can perceive the size, length, height, area and volume of the space and use spatial adjectives to describe the result of our perception. This language performance of basic sense towards space is a common phenomenon in all languages. The spatial dimension is divided into one dimension, two dimensions and three dimensions according to the spatial features. “长” in Chinese and “길다” in Korean is the language performance of human’s cognition towards the length of an object in one dimension. Based on the analysis of the projection in meaning of these words, we find that “长” and “길다” have quite similar meaning in source domain, and in their respective meaning constructions, they demonstrate the projection to other target domains. Among which some of the target domains are the same. We also find, however, though the target domains are the same, the specific semantic meanings after projection do not show one hundred percent equivalence. Based on Contrastive Linguistics and Cognitive Linguistics theories, the paper aims to analyze the similarities and differences of both words in the course of projection and discuss their characteristics in the projection.

      • SCISCIESCOPUSKCI등재

        Effect of Molybdenum and Chromium on Hardenability of Low-Carbon Boron-Added Steels

        ( Fu Tao Han ),( Byoung Chul Hwang ),( Dong Woo Suh ),( Zuo Cheng Wang ),( Duk Lak Lee ),( Sung Joon Kim ) 대한금속재료학회 ( 구 대한금속학회 ) 2008 METALS AND MATERIALS International Vol.14 No.6

        The hardenability of low-carbon boron-added steels containing molybdenum or chromium was studied using dilatometry, thermodynamic calculations, and secondary ion mass spectroscopy (SIMS). The combined addition of boron and molybdenum was found to be more effective than that of boron and chromium in enhancing the hardenability of boron-added steels. In particular, the addition of 0.5 wt.% molybdenum to the boron-added steel almost completely suppressed the formation of polygonal ferrite even at a slow cooling rate of 0.5℃/s. The synergistic effect of the combined addition of molybdenum and boron is thought to be due to both the suppression of M23(C,B)6 precipitation resulting from the deterioration of phase stability and the reduction of carbon diffusivity by the molybdenum addition.

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