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Norio Nakatsuji,Eihachiro Kawase,Takamichi Miyazaki,Itsunari Minami,Kazuhiro Aiba 한국조직공학과 재생의학회 2013 조직공학과 재생의학 Vol.10 No.4
We are recently developing novel technologies for large-scale production of high-quality human pluripotent stem cells (hPSCs) by development of defined and robust adhesion molecules for hPSCs as well as other culture technologies. We are also working on control of stem cells with chemical compounds and micro-fabricated materials for growth and differentiation of ES/iPS cells in collaboration with chemical biology groups and micro-engineering groups. So far, we have identified novel small molecules which can induce efficient and robust cardiomyocyte differentiation from many human ES and iPS cell lines in completely defined and xeno-free conditions. Finally, we have created and investigated various model cells from human ES and iPS cell lines. They include neurodegenerative disease model cells, such as Alzheimer, ALS and Huntington disease models, which are produced by genetic modification of stem cell lines and differentiation into relevant cells in each disease.
배준우,임재원,김선중,Kouji Mimura,Takamichi Miyazaki,Masahito Uchikoshi,Minoru Isshiki 대한금속·재료학회 2010 METALS AND MATERIALS International Vol.16 No.3
ZrO2 dielectric layers were prepared by a two-step process, a deposition of pure Zr film with and without a negative substrate bias voltage and a subsequent oxidation of the Zr films. We focused on the effect of the negative substrate bias voltage on the Zr film deposition and the subsequent oxidation of the Zr films. As a result, the Zr film deposited at the substrate bias voltage of −50 V (Vs = −50 V) was found to have a high intensity peak of Zr (100) and a uniform and smooth surface. From the capacitance-voltage and currentvoltage measurements of the ZrO2 films, a high dielectric constant of 21 and the equivalent oxide thickness (EOT) of 2.6 nm were obtained on the oxidation layer of the Zr film deposited at Vs = −50 V. On the other hand, a low dielectric constant of 15 and the EOT of 3.6 nm was obtained on that of the Zr film deposited at Vs = 0 V. The leakage current density of the ZrO2 film (Vs = −50 V) was 5.69×10−4A/cm 2, and this value was much lower than the 1.21×10−4A/cm 2for the ZrO2 film (Vs = 0 V). It was found that the two-step process by subsequent oxidation after film deposition using a negative substrate bias voltage is useful for obtaining high-quality dielectric layers.
Interface State and Coercivity in Nd-Fe-B/Dy Films
Jin Umezawa,Yoshiki Sakai,Kunihiro Koike,Daisuke Ogawa,Yoshiyuki Mizuno,Hiroaki Kato,Takamichi Miyazaki,Yasuo Ando 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
We fabricated a model interface system, which consised of a Nd2Fe14B layer with Dy overlayers,in order to study the relationship between the microstructure near the interface and the coercivity. The coercivity Hc of the 1-µm-thick Nd-Fe-B films with a Dy overlayer was enhanced by thermaldiffusion of Dy atoms from the film’s surface into the Nd-Fe-B layer. The Nd-Fe-B/Dy films annealedat 700℃ showed a significant increase in the Hc of up to about 17 kOe. The maximum increasein the value of the coercivity ΔHc of the annealed films with a Dy overlayer was approximately 13kOe. The XRD measurement suggested the existence of rare-earth oxides (NdO and Dy2O3) in theDy-coated films with high value of the ΔHc.
Evaluation of Interlayer Exchange Coupling in α-Fe(100)/Nd2Fe14B(001) Films
Daisuke Ogawa,Kunihiro Koike,Hiroaki Kato,Shigemi Mizukami,Takamichi Miyazaki,Mikihiko Oogane,Yasuo Ando 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
We fabricated α-Fe(100)/Nd2Fe14B(001) bilayer films with different thicknesses values of the-Fe layer on MgO(100) substrates by using an ultra-high-vacuum (UHV) magnetron sputteringsystem. The exchange coupling constant at the heterointerfaces of α-Fe(100)/Nd2Fe14B(001) wasevaluated by analyzing the magnetization curves and the ferromagnetic resonance (FMR) spectra. We observed a significant lower shift of the α-Fe resonance field compared to that of the α-Fe singlelayer irrespective of the Fe-layer thickness, which suggests the existence of an internal field owingto a positive exchange coupling between the -Fe(100) and the Nd2Fe14B(001) layers.
Structural and Magnetic Properties in Annealed FePt-Bx (x = 0.05 and 0.33) Thin Films
Young-Min LEE,Chan-Gyu LEE,Bon-Heun KOO,Byeong-Seon LEE,Osamu Kitakami,Satoshi Okamoto,Takamichi Miyazaki,Yutaka Shimada 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.3
Multi-layer films of MgO20 nm/(FePt-Bx)50 nm/MgO20 nm were deposited on Si (100) substrates by RF magnetron sputtering. The B content (x) of the thin films was found to be about 5 and 33 at.% by using wavelength dispersive spectroscopy (WDX). In the (FePt)0.67B0.33 film an excess of B in the FePt film led to an amorphous structure in the as-deposited film, which changed to an ordered cubic structure on annealing. However, the (FePt)0.95B0.05 film started to show a phase transformation from the disordered fcc structure to the ordered L10 phase with an fct structure at 350 C and was remarkably transformed to a L10 structure at about 500 C on post-annealing. The maximum coercivities (Hc) of the (FePt)0.95B0.05 and the (FePt)0.67B0.33 films were found to be 9.1 and 2.9 kOe after annealing at 600 C for 1 hr, respectively.
Cho, Seungchan,Okayasu, Rin,Kikuchi, Keiko,Choi, Moonhee,Park, Jehong,Jo, Ilguk,Lee, Sang-Bok,Kwon, Hansang,Kim, Yangdo,Miyazaki, Takamichi,Kawasaki, Akira Elsevier 2019 Scripta materialia Vol.159 No.-
<P><B>Abstract</B></P> <P>We successfully fabricated a controllable intragranular pore containing hydroxyapatite (HA) by the combination of an electric current assisted sintering and pre-heat treatment process. The microstructure and mechanical properties of the sintered HA bulk with and without intragranular pores were investigated in this study. Fully densified HA fabricated by the combination of an electric assisted sintering and pre-heat treatment process showed extremely superior mechanical properties. Meanwhile, hierarchically structured porous HA consisting of nanosized intragranular pores without macropores in the grain boundary showed dramatically decreased elastic modulus by different fracture mechanism compared with fully densified HA.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>