Epidural anesthesia for pilonidal sinus surgery: ropivacaine versus levobupivacaine

Zeynep Nur Orhon,Emine Nursen Koltka,Sibel Devrim,Sevil Tüfekçi,Serkan Doğru,Melek Çelik 대한마취통증의학회 2015 Korean Journal of Anesthesiology Vol.68 No.2

Background: Epidural anesthesia is one of the best options for lower abdominal and lower limb surgery. However, therehave been insufficient reports regarding the use of epidural anesthesia for pilonidal sinus surgery. The present study wasperformed to compare the clinical profiles of epidural block performed with 0.75% levobupivacaine and 0.75% ropivacainein this procedure. Methods: Thirty patients undergoing pilonidal sinus surgery were randomly allocated into two groups: one group receivedlevobupivacaine and the other received ropivacaine at 0.75% in a volume of 10 ml. Arterial blood pressure, heartrate, oxygen saturation, the onset time of analgesia and duration of block, highest sensory block level, perioperative andpostoperative side effects, and patients’ and surgeons’ satisfaction were recorded. Results: Hemodynamic stability was maintained in both groups throughout surgery. The onset time of analgesia (thetime from epidural injection of local anesthetic to reach L2 sensorial block) was 6.26 ± 3.49 min in the levobupivacainegroup and 4.06 ± 1.75 min in the ropivacaine group (P = 0.116). The duration of sensorial block (time for regression ofsensory block to L2) was 297.73 ± 70.94 min in group L and 332.40 ± 102.22 min in group R (P = 0.110). Motor block wasnot seen in any of the patients in the study groups. Patients’ and surgeons’ satisfaction with the anesthetic technique weremostly excellent in both groups. Conclusions: In patients undergoing pilonidal sinus surgery, both levobupivacaine and ropivacaine produce rapid andexcellent epidural block without leading to motor block or significant side effects. Although not statistically significant,the onset time of anesthesia was shorter and the duration of effect was longer with ropivacaine than with levobupivacainein this study.

Ambient vibration testing of Berta Highway Bridge with post-tension tendons

Fatma Nur Kudu,Alemdar Bayraktar,Pelin Gündeş Bakir,Temel Türker,Ahmet Can Altunişik 국제구조공학회 2014 Steel and Composite Structures, An International J Vol.16 No.1

The aim of this study is to determine the dynamic characteristics of long reinforced concrete highway bridges with post-tension tendons using analytical and experimental methods. It is known that the deck length and height of bridges are affected the dynamic characteristics considerably. For this purpose, Berta Bridge constructed in deep valley, in Artvin, Turkey, is selected as an application. The Bridge has two piers with height of 109.245 m and 85.193 m, and the total length of deck is 340.0 m. Analytical and experimental studies are carried out on Berta Bridge which was built in accordance with the balanced cantilever method. Finite Element Method (FEM) and Operational Modal Analysis (OMA) which considers ambient vibration data were used in analytical and experimental studies, respectively. Finite element model of the bridge is created by using SAP2000 program to obtain analytical dynamic characteristics such as the natural frequencies and mode shapes. The ambient vibration tests are performed using Operational Modal Analysis under wind and human loads. Enhanced Frequency Domain Decomposition (EFDD) and Stochastic Subspace Identification (SSI) methods are used to obtain experimental dynamic characteristics like natural frequencies, mode shapes and damping ratios. At the end of the study, analytical and experimental dynamic characteristic are compared with each other and the finite element model of the bridge was updated considering the material properties and boundary conditions. It is emphasized that Operational Modal Analysis method based on the ambient vibrations can be used safely to determine the dynamic characteristics, to update the finite element models, and to monitor the structural health of long reinforced concrete highway bridges constructed with the balanced cantilever method.

Fetal programming: could intrauterin life affect health status in adulthood?

( Hande Nur Onur Öztürk ),( Perim Fatma Türker ) 대한산부인과학회 2021 Obstetrics & Gynecology Science Vol.64 No.6

Intrauterine life is one of the most important periods of life. As the development of the fetus continues, the mechanisms that affect adult health also begin to mature. With the hypothesis denoted “fetal programming,” it is thought that the presence of endocrinological disorders, toxins, infectious agents, the nutritional status of a mother, and nutrients related to placental functionality all have an effect on future life. Therefore, the fetus must adapt to the environment for survival. These adaptations may be involved the redistribution of metabolic, hormonal, or cardiac outputs in an effort to protect the brain, which is one of the important organs, as well as the slowing of growth to meet nutritional requirements. Unlike lifestyle changes or treatments received in adult life, the early developmental period tends to have a lasting effect on the structure and functionality of the body. In this review, fetal programming and the effects of fetal programming are discussed.

Immobilization of Glucose Oxidase Attached to New Nanospheres Including Azomethine

Nurbanu Özdem,Nurşen Sarı,Elvan Hasanoğlu Özkan,Fatma Arslan,Hayrettin Tümtürk 한국고분자학회 2014 Macromolecular Research Vol.22 No.12

New nanosphere supports were prepared and characterized for the immobilization of glucose oxidasefrom Aspergillus niger. Nanoparticles ((APS-tio), (APS-tioCH3), and (APS-tioCl)) modified (aminomethyl)polystyrene(APS) with some tyophenealdehyde derivatives were synthesized by means of condensation and we investigated the enzymaticproperties of glucose oxidase enzyme (GOx) immobilized on them. Modified polystyrene was characterized by IRspectra, gel permeation chromatography and scanning electron microscopy. Immobilized GOx on (APS-tioCH3) showed aoptimum pH, whereas immobilized GOx on (APS-tio) and (APS-tioCl) performed the optimum condition at two pHs.

Phosphate removal from water using an iron oxide impregnated strong base anion exchange resin

T. Nur,S Vigneswaran,M.A.H. Johir,P. Loganathan,T. Nguyen,J. Kandasamy 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

Removing phosphate from water is important as it causes eutrophication, which in turn has a harmful effect on aquatic life, resulting in a reduction in biodiversity. On the other hand, recovery of phosphate from phosphorus containing wastewater is essential for developing an alternative source of phosphorus to overcome the global challenge of phosphorus scarcity. Phosphate removal from aqueous solutions was studied using an iron oxide impregnated strong base anion exchange resin, Purolite FerrIX A33E in batch and fixed-bed column experiments. Phosphate adsorption in the batch study satisfactorily fitted to the Langmuir isotherm with a maximum adsorption capacity of 48 mg P/g. In the column study, increase in inlet phosphate concentration (5–30 mg P/L), and filtration velocity (2.5–10 m/h) resulted in faster breakthrough times and increase in breakthrough adsorption capacities. Increase in bed height (3–19 cm) also increased adsorption capacity but the breakthrough time was slower. The breakthrough data were reasonably well described using the empirical models of Bohart–Adams, Thomas, and Yoon–Nelson, except for high bed heights. Phosphate adsorbed was effectively desorbed using 1 M NaOH and the adsorbent was regenerated after each of three adsorption/desorption cycles by maintaining the adsorption capacity at >90% of the original value. Greater than 99.5% of the desorbed P was recovered by precipitation using CaCl2.

Identification of heat shock protein70-2 and protamine-1 mRNA, proteins, and analyses of their association with fertility using frozen-thawed sperm in Madura bulls

Zulfi Nur Amrina Rosyada,Berlin Pandapotan Pardede,Ekayanti Mulyawati Kaiin,Ligaya I.T.A Tumbelaka,Dedy Duryadi Solihin,Bambang Purwantara,Mokhamad Fakhrul Ulum Asian Australasian Association of Animal Productio 2023 Animal Bioscience Vol.36 No.12

Objective: This study aims to identify heat shock protein70-2 (HSP70-2) and protamine-1 (PRM1) mRNA and protein in Madura bull sperm and demonstrate their relation as bull fertility biomarkers. Methods: The Madura bull fertility rates were grouped based on the percentage of first service conception rate (%FSCR) as high fertility (HF) (79.04%; n = 4), and low fertility (LF) (65.84%; n = 4). mRNA of HSP70-2 and PRM1 with peptidylprolyl isomerase A (PPIA) as a housekeeping gene were determined by quantitative real-time polymerase chain reaction, while enzyme-linked immunoassay was used to measure protein abundance. In the post-thawed semen samples, sperm motility, viability, acrosome integrity, and sperm DNA fragmentation index were analyzed. Data analysis was performed on the measured parameters of semen quality, relative mRNA expression, and protein abundance of HSP70-2 and PRM1, among the bulls with various fertility levels (HF and LF) in a one-way analysis of variance analysis. The Pearson correlation was used to analyze the relationship between semen quality, mRNA, proteins, and fertility rate. Results: Relative mRNA expression and protein abundance of HSP70-2 and PRM1 were detected and were found to be highly expressed in bulls with HF (p<0.05) and were associated with several parameters of semen quality. Conclusion: HSP70-2 and PRM1 mRNA and protein molecules have great potential to serve as molecular markers for determining bull fertility.

나노입자 적층시스템을 이용한 그라파이트 적층 및 응용

천두만(D. M. Chun),Mohammad Nur E Alam Al Nasim,Mohaned Mohammed Mahmoud Moham,홍성태(S. T. Hong) Korean Society for Precision Engineering 2018 한국정밀공학회 학술발표대회 논문집 Vol.2018 No.10월