http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : T. Cowan (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
FACTORS AFFECTING PRODUCTIVITY ON DAIRY FARMS IN TROPICAL AND SUB-TROPICAL ENVIRONMENTS
Kerr, D.V.,Davison, T.M.,Cowan, R.T.,Chaseling, J. Asian Australasian Association of Animal Productio 1995 Animal Bioscience Vol.8 No.5
The major factors affecting productivity on daily farms in Queensland, Australia, were determined using the stepwise linear regression approach. The data were obtained from a survey conducted on the total population of daily farms in Queensland in 1987. These data were divided into six major dailying regions. The technique was applied using 12 independent variables believed by a panel of experienced research and extension personnel to exert the most influence on milk production. The regression equations were all significant (p < 0.001) with the percentage coefficients of determination ranging from 62 to 76% for equations developed using' total farm milk: production as the dependent variable. Three of the variables affecting total farm milk: production were found to be common to all six regions. These were; the amount of supplementary energy fed, the area set aside to irrigate winter feed and the size of the area used for dailying. Higher production farms appeared to be more efficient in that they consistently produced milk production levels higher than those estimated from the regression equation for their region. Other methods of analysis including robust regression and non linear regression techniques were unsuccessful in overcoming this problem and allowing development of a model appropriate for farms at all levels of production.
-
The nELBE Neutron Time of Flight Facility
A. R. Junghans,E. Altstadt,R. Beyer,E. Birgersson,T. Cowan,A. Ferrari,R. Hannaske,A. Matic,K. D. Schilling,R. Schlenk,S. Schneider,R. Schwengner,A. Wagner,F. -P. Weiss,D. Gehre,E. Grosse 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.23
At the superconducting electron linear accelerator ELBE at Forschungszentrum Dresden-Rossendorf the neutron time-of-flight facility nELBE has become operational. Fast neutrons in the energy range from 200 keV to 10 MeV are produced by the pulsed electron beam from ELBE impinging on a liquid lead circuit as a radiator. The short beam pulses of 10 ps provide the basis for an excellent time resolution for neutron time-of-flight experiments, giving an energy resolution of about <1% at 1 MeV with a short flight path of 5 m. The neutron intensity on target is ∼4·10^4 n/(cm^2 s) using an electron bunch charge of 77 pC and 100 kHz pulse repetition rate. The energy range of the neutrons produced is well suited for neutron cross section measurements relevant for the development of Generation IV reactor systems and for the transmutation of nuclear waste. First measurements of inelastic neutron scattering cross sections have been performed and will be presented.
-
Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving
Li, Xuan,Carreria, Maria B.,Witonsky, Kailyn R.,Zeric, Tamara,Lofaro, Olivia M.,Bossert, Jennifer M.,Zhang, Jianjun,Surjono, Felicia,Richie, Christopher T.,Harvey, Brandon K.,Son, Hyeon,Cowan, Christo Elsevier 2018 Biological psychiatry Vol.84 No.3
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Methamphetamine (meth) seeking progressively increases after withdrawal (incubation of meth craving). We previously demonstrated an association between histone deacetylase 5 (HDAC5) gene expression in the rat dorsal striatum and incubation of meth craving. Here we used viral constructs to study the causal role of dorsal striatum HDAC5 in this incubation.</P> <P><B>Methods</B></P> <P>In experiment 1 (overexpression), we injected an adeno-associated virus bilaterally into dorsal striatum to express either green fluorescent protein (control) or a mutant form of HDAC5, which strongly localized to the nucleus. After training rats to self-administer meth (10 days, 9 hours/day), we tested the rats for relapse to meth seeking on withdrawal days 2 and 30. In experiment 2 (knockdown), we injected an adeno-associated virus bilaterally into the dorsal striatum to express a short hairpin RNA either against luciferase (control) or against HDAC5. After training rats to self-administer meth, we tested the rats for relapse on withdrawal days 2 and 30. We also measured gene expression of other HDACs and potential HDAC5 downstream targets.</P> <P><B>Results</B></P> <P>We found that HDAC5 overexpression in dorsal striatum increased meth seeking on withdrawal day 30 but not day 2. In contrast, HDAC5 knockdown in the dorsal striatum decreased meth seeking on withdrawal day 30 but not on day 2; this manipulation also altered other HDACs (<I>Hdac1</I> and <I>Hdac4</I>) and potential HDAC5 targets (<I>Gnb4</I> and <I>Suv39h1</I>).</P> <P><B>Conclusions</B></P> <P>Results demonstrate a novel role of dorsal striatum HDAC5 in incubation of meth craving. These findings also set up future work to identify HDAC5 targets that mediate this incubation.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
