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      • 인터넷상거래에서 공동물류 활용 방안에 관한 연구

        서필교,주상호 한국유통정보학회 2000 유통정보학회지 Vol.3 No.1

        In a traditional business environment purchase ordered products are normally obtained right after they are paid, however in an Internet business environment except for the digitized products we have to wait until they are delivered to the delivery address. The delivery cost occupies a big portion of the total buying cost and the delivery time is an important factor to facilitate Internet business. When we use Internet shops, their Internet addresses are to be memorized. Each Internet shop has various ways of payment and delivery system. Meta shopping mall is a mall of malls where lots of Internet shopping malls are doing their own business. In a meta shopping mall system, an efficient logistics and distribution system can be used to minimize the total logistics and distribution costs. In this paper and 0/1 integer model and its solution procedure are proposed to minimize the total logistics and distribution cost and to meet the delivery time requirement. And also the application areas of this model is proposed.

      • 가시광을 이용한 ZnS/ZnO 상에서의 광촉매 반응에 의한 물로부터의 수소생성

        서승광,윤필상,이한수,이호인 한국공업화학회 2003 응용화학 Vol.7 No.2

        The pure ZnS can not absorb visible light because of its large band gap of 3.6eV. The ZnO/ZnS was obtained from partial oxidation of ZnS, and its band gap was 2.5eV where visible light can be absorbed. From XRD analysis, it was confirmed that only ZnO was formed during oxidation process but not ZnSO₄. In case of ZnO/ZnS, the quantum efficiency for the hydrogen evolution from water was 0.87% under visible light irradiation. In order to improve the interaction between ZnO and ZnS, ZnS/ZnO was prepared by precipitating ZnS on ZnO. After calcination of ZnS/ZnO, the band gap became narrow. The pure ZnO and the physically mixed ZnS-ZnO could not absorb visible light, but the ZnS-doped ZnO (ZnS/ZnO) could do. The band gap of pure ZnO was 3.2 eV and that of ZnS/ZnO was 2.5ev. The best activity was obtained when clcination temperature and time were 500 ℃ and 1 h, respectively. The quantum efficiency of ZnS/ZnO for the reaction was 3.29%.

      • KCI등재후보
      • 소수성 NaY Zeolite의 합성과 탈알루미나의 특성

        서동남,하종필,구상모,이해진,김익진 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

        NaY형 Zeolite는 현재 그들의 촉매적 특성과 흡착성 그리고 이온 교환성들을 이용하여 산업에 중요하게 사용되어지고 있다. 본 실험은 고온 스팀을 이용한 방법과 산처리에 의한 방법으로 탈알루미나의 효과를 확인하는 실험을 하였다. 먼저 SiO_2/Al_2O_3 몰비가 4∼6인 합성 NaY zeolite를 분위기 소성로에 넣고 증기발생 장치를 이용하여 500℃에서 고온 스팀을 분위기 소성로에서 일정하게 주입하였다. 에에 따른 결과는 탈알루미나 처리 후의 XRF와 BET의 결과로 탈알루미나 처리에 따라서 SiO_2/Al_2O_3의 몰비가 20.6에서 21까지 증가한 것을 알 수 있으며 또한 BET의 결과에서 탈알루미나 처리에 의해서 비표면적이 증가한 것을 확인할 수 있으며 특히 meso pore area의 증가는 탈알루미나에 의해서 zeolite의 골격구조가 일부 파괴되었음을 알 수 있다.

      • 실험적 부자 시신경병증에서 Methylprednisolone의 효능

        신재필,이상희,서형덕,김인택 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1

        동물실험에서 aconite 또는 aconitine은 신경계통에 독성을 나타낸다고 이미 알려져 있다. 그러한 독성은 시유발전위와 병리조직에서 탈수초증으로 나타난다. 저자들은 실험적으로 aconite을 주입하여 탈수초신경증을 일으킨 후 고용량이 methylprednisolone(MP)투여가 효능이 있는지를 알아보고자 하였다. Aconite를 복강내 주입하고 곧 이어 가토의 이연정맥으로 MP를 주입한 군과 aconite만을 주입한 군으로 나누었고 이들을 서로 비교하였다. 그리고 이 두 군을 정상군과도 비교하였다. 시유발전위에서 aconite를 주입후 MP를 투여한 군에서 aconite만을 주입한 군에 비하여 onset latency와 peak latency 그리고 진폭 모두에서 2주째에 통계학적으로 의미있게 회복되었으나 (p<0.05) 정상군과 비교하여 의미있는 차이를 나타내지 아니하였다. 그러나 정상군과 비교하여 1개월과 2개월에서 onset latency은 의미있게 지연되었고 (p<0.05) peak latency와 진폭은 다소 회복되었으나 정상군의 평균값에는 미치지 못하였다. 병리조직에서 MP으로 치료한 군과 aconite만을 주입한 군 모두에서 수초의 탈수초변화가 관찰되었으나 MP으로 치료한 군은 상대적으로 탈수초변화가 현저하지 아니하였다. 본 연구에서 실험적으로 가토에 aconite를 전신에 투여하여 시신경병증을 일으킨 후 고용량의 MP를 즉시 투여한 경우에 시신경의 기능을 정상상태까지 회복시키는데는 한계가 있으나 부분적으로 시신경의 기능을 회복시키는데 도움이 될 것으로 생각된다(한안지 37:1730~1740, 1996). Studies in animals indicate that aconitine or aconite has toxic effects in the visual system of a rabbit model. Such a toxic effects causes myelo-optic neuropathy in the visually evoked cortical potential(VECP) and histopathologic studies. Whether the administration of intravenous high-does of methyprednisolone(MP) in the myelo-optic neuropathy caused by aconitine(1.5㎖/㎏, equivalent to 0.7㎎/㎏ of aconitine) is experimentally effective remains uncertain. The group treated with MP(daily 30㎎/㎏×2 for 3 days followed by 15㎎/㎏ for 3 days) in addition to aconite was compared with the aconite alone group and the normal control group. In the MP treated group, increased recovery of onset latency, peak latency, and amplitude in VECP in comparision with the aconite alone group was recorded at 2 weeks(p<0.05). The MP treated group in comparision with the normal control group showed a significant delay in onset latency at 1 month and 2 months(p<0.05). But, the amplitude in both the MP treated group and the aconite alone group increased at 2 months and did not show a significant difference in comparision with the normal group(p<0.05). In histopathologic study, pathologic findings of myelin sheath in the MP treated group were less severe than in the aconite alone group generally. The true benefit of high-does MP was at least clear within 2 weeks. The authors conclude that treatment with intravenous high-does MP immediate after aconite injection may have some beneficial effects in recovery of neurologic function although such a treatment do no have the definite recovery in aconite induced myelo-optic neuropathy(J Korean Ophthalmol Soc 37:1730~1740, 1996).

      • 캔터키 블루그래스에 의한 잔디 조성 기술 개발

        이재필,조용인,서한용,이상재,김태준,한인송,김두환 建國大學校附設農業資源開發硏究所 2001 農資源開發論集 Vol.23 No.-

        Seed sowing is the major method for the establishment of cool-season grasses at the soccer fields, golf courses, etc. Germination speed of kentucky bluegrass(Poa prantensis L.: KB) is much slower than the other cool-season grasses. This study was conducted to solve the problems at the early stage of establishment with KB. The best priming conditions of KB, drying method after soaking in the water, and covering materials will be selected. To reduce irrigation frequency and quantity for seed germination, seeds of KB were exposed to the different soaking temperature(4, 20, 25, 30℃). soaking durations(3, 6, 10, 13, 19, 23 days), storage periods(3, 6, 9 days), storage humidities(30, 50, 100%), shading rate(0, 50, 100%), drying methods(dry in the air, heating, mix soaked seed with profile=1:2), and covering materials(70% shade net, fiber net). The optimum soaking temperature and duration for the seed priming of KB were 20℃ and 10 days, respectively. The optimum storage period and humidity were 3 days and 100%, respectively, Under 50% shading, germination rate was the highest. In drying method after soaking, mixture of seeds and profile(1:2) was optimum for sowing. Using the thin fiber net as covering material after sowing was good for not moving seeds and improved germination speed and rate.

      • TNF-α 유전자형과 방광암과의 관계

        정필두,김은정,엄민식,서정원,윤석중,김종석,이상철,김원재 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

        연구목적: TNF-α는 일부 종양의 종양화 과정과 관련이 있는 것으로 알려져 있다. 본 연구는 TNF-α 발현에 영향을 미치는 TNF-α 촉진자 -308 부위의 유전적 다형성이 방광암과 관련이 있는지 유무를 알고자 시행하였다. 대상 및 방법: 유전자 분석을 위하여 환자 113명 및 대조군 109명으로부터 혈액을 채취하여 genomic DNA를 분리한 후 PCR-RFLP 및 direct DNA sequencing을 통하여 TNF-α유전자의 다형성을 조사하여 방광암의 발생, 병기 및 분화도와 비교 검토하였다. 결과: TNF-α 촉진자 -308 부위의 유전형은 대조군에서는 GG형이 83.5%(90례 및 GA형이 16.5%(19례)로 관찰되었으며 AA형은 없었다. 환자군에서는 GG 형이 85.4%(97례), GA형 및 AA형은 각각 13.1%(15례)및 0.8%(1례)에서 관찰되었다. 두 군 모두에서 GG형이 가장 많이 나타났으며 다음으로 GA형을 보이고 AA형은 1례의 방광암 환자에서만 관찰되었다. -308부위의 경우도 두 군 사이에 유전자형의 차이는 없었다(p=0.259) 분화도별 분포를 보면 grade I이 20례, grade II가 49례, grade Ⅲ은 34례였고 병기별로 표재성인 경우가 90례였으며 침윤성은 14례였다. 분화도가 나빠질수록 GA형이 증가하였다(p=0.04). 그러나 병기와 TNF-α promoter -308부위의 유전자형 사이에는 유의한 상관 관계가 없었다(p=0.123). 결론: 방광암 환자의 혈액에서 GA genotype이 관찰되는 경우, 분화도가 나쁠 가능성이 매우 높기 때문에 좀 더 적극적인 치료와 세밀한 추적관찰을 함으로써 방광암으로 인한 사망과 암의 진행을 예방할 수 있을 것으로 기대한다. Purpose : Tumor necrosis factor-alpha (TNF-α) is involved in tumorigenesis of several cancers as an endogenous tumor promoter. The purpose of this study was to investigate whether genetic polymorphism of TNF-α promoter region (-308) was associated with human bladder tumor. Materials and Methods: The DNA from 113 and 109 respective blood samples of bladder tumor Patients and control group was analyzed by PCR-based restriction fragment length polymorphism (RFLP) and direct DNA sequencing methods to characterize the genetic polymorphism of -308 promoter region of the TNF-α gene in bladder tumor patients. We compared the association of bladder tumor with genetic Polymorphism of TNF-α promoter region(-308) in relation to the stage, grade, recurrence and progressio. Results : Eighty-six percents(97/113) of bladder tumor patients and 83.5% (90/109) of control group showed genotype GG at -308 region of TNF-α. Difference in genetic variations of TNF-α promoter (-308) did not exist between bladder tumor patients and control group(p=0.259). Tumor grade was significantly related to the GA genotype (p=0.04). The higher is the grade in bladder tumor, the more frequent was the GA genotype. Tumor stage, recurrence and progression were not significantly associated with genetic polymorphism of TNF-α promoter region (-308). Conclusion: The GA genotype of TNF-a promoter region (-308) had a significant impact on TNF-α production and was related to higher grade tumor compared to GG genotype. TNF-α serum levels in bladder tumor patients were significantly higher than controls. These data suggested that TNF-α might involve the tumorigenesis of the bladder rather than treatment or prevention of bladder tumor.

      • 한국형 대형 할인점의 상품배치의 의사결정

        주상호,서필교 한국유통정보학회 1999 유통정보학회지 Vol.2 No.1

        The discount store we are dealing with in this study is typically located near a large scale apartment complex with high population density. In this type of discount store, we easily encounter the shopping environment in which customer movements are mixed in all directions and jammed in the aisle. This bothers the customers to shop in a comfortable and relaxed mood and, as a result, reduces the possibility of impulse purchasing. We propose a product display assignment problem in a large scale discount retailor store operation in Korea. We present a decision making model in which the product assignment is determined to minimize the customer flow congestion caused by customer movement for shopping in the display area. Due to the complexity of the problem, we propose a heuristic algorithm to obtain upper bounds on the optimum value. We also suggest a set of approaches to resolve the disorder unbalance among the groups of product display corners. We discuss the management of data base associated with the decision making problem. At the end we state the research contributions and further directions from operations management view point.

      • KCI등재

        응급실 내원시 예상치 못한 사망 환자의 예측 인자

        김욱진,서정필,정성필,황태식,이한식 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

        Background: Unexpected deaths of the patients at ED are surprising to the medical staffs as well as the families. It may also increase the possibilities of medico-legal problems. This study was conducted to review the unexpected death in ED and find the predictive factors leading patients to unexpected death. Methods: A retrospective study with reviewing available medical records of 183 patients who were expired at Ed of Shinchon Severance Hospital from Mar. 1997 to Feb. 1998 and 103 patients of Youngdong Severance Hospital from Mar. 1996 to Feb. 1998 was done. Analyses were done on 30 variables of physical findings, laboratory results, procedures and therapies. We used univariate analysis such as t-test and x²-test and multiple logistic regression analysis. Results: Of the total 286 deaths in Ed, 153 cases were enrolled in this analysis. The number of unexpected deaths were 76. Age, mental status, fraction of neutrophil count, BUN level, whether endotracheal intubation was done, use of inotropics were the factors with statistical significance on the univariate analysis, but only comatose mentality, endotracheal intubated case, and use of the inotropics were significant on logistic regression analysis. The longer the ED length of stay, the higher the rate of mortality and unexpected death. Conclusion: This result suggest that medical attention is needed on the patients with comatose decreased mental status, endotracheally intubated case and needing inotropic agents to prevent unexpected deaths shortening the ED length of stay may also be a factor for decrease the unexpected death rate.

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