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- 저자 : Stefania Colantuono (검색결과 1 건)
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Health Related Quality of Life in Common Variable Immunodeficiency
Isabella Quinti,Stefano Tabolli,Cristina Di Pietro,Helene Martini,Anna Maria Pesce,Francesca Lombardi,Maddalena Baumghartner,Stefania Colantuono,Cinzia Milito 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.3
Purpose: To quantify the health related quality of life in primary immunodeficiency patients. Materials and Methods: We used generic health status and general psychological health questionnaires to determine the range of issues that needed to be considered in examining the burden of common variable immunodeficiency (CVID). Results: The health status of patients with CVID was lower than that observed in normal subjects. Overall, Role-Physical and General Health scales correlated with a poorer clinical status. Surprisingly, the duration of disease did not influence health status. Being female, older, General Health Questionnaire-positive and alexithymic proved to be major risk factors associated with a poor health status. Patients with chronic lung disease and chronic diarrhea had the lowest values on the Medical Outcome Study, Short Form SF-36 (SF-36) scales. Disease severity perception was associated with the General Health Questionnaire and alexithymia status. Limitations in daily activities as a result of lower physical health were the major problems facing common variable immunodeficiency patients. Conclusion: Our data underlined the importance of conducting a periodical health related quality of life assessment on patients with primary antibody deficiencies and, moreover, stressed the necessity of providing psychological support to at risk patients.
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