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        The Effect of Adding Honey to Zinc in the Treatment of Diarrhea in Children

        Abolfazl Mahyar,Parviz Ayazi,Mohammad Reza Shaftaroni,Sonia Oveisi,Reza Dalirani,Shiva Esmaeili 대한가정의학회 2022 Korean Journal of Family Medicine Vol.43 No.3

        Background: Honey has been used in medicine since ancient times. Limited reports are available to indicate its antibacterial, antiviral, and antidiarrheal properties. This study aimed to determine the effect of honey on acute di-arrhea in children.Methods: This randomized clinical trial included 80 children with acute diarrhea. Forty children received honey and zinc gluconate (trial group) and 40 received only zinc gluconate (control group). After treatment, vomiting/di-arrhea duration, the recovery time, and the duration of hospitalization were compared between the groups.Results: Among the 40 children in the trial group, 19 were male and 21 were female. In the control group, 25 chil-dren were male and 15 female (P=0.26). After initiating treatment, the duration of diarrhea, recovery time, and the duration of hospitalization was significantly shorter in the trial group than in the control group (P<0.05).Conclusion: This study showed that honey with zinc gluconate reduces the duration of diarrhea, accelerates the re-covery time, and shortens the duration of hospitalization.

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        Are Clinical, Laboratory, and Imaging Markers Suitable Predictors of Vesicoureteral Reflux in Children With Their First Febrile Urinary Tract Infection?

        Abolfazl Mahyar,Parviz Ayazi,Shiva Mavadati,Sonia Oveisi,Morteza Habibi,Shiva Esmaeily 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.8

        Purpose: This study was conducted to determine the predictive value of clinical, laboratory,and imaging variables for the diagnosis of vesicoureteral reflux in children withtheir first febrile urinary tract infection. Materials and Methods: One hundred fifty-three children with their first febrile urinarytract infection were divided into two groups according to the results of voiding cystourethrography:60 children with vesicoureteral reflux and 93 children without. Thesensitivity, specificity, positive and negative predictive value, likelihood ratio (positiveand negative), and accuracy of the clinical, laboratory, and imaging variables for thediagnosis of vesicoureteral reflux were determined. Results: Of the 153 children with febrile urinary tract infection, 60 patients (39.2%)had vesicoureteral reflux. There were significant differences between the two groupsregarding fever>38oC, suprapubic pain, C-reactive protein quantitative level, numberof red blood cells in the urine, and results of renal ultrasound and dimercaptosuccinicacid renal scanning (p<0.05). There were significant positive correlations between fever>38.2oC and dimercaptosuccinic acid renal scanning and vesicoureteral reflux. Also, there were significant positive correlations between the erythrocyte sedimentationrate, positive urinary nitrite test, hyaline cast, and renal ultrasound andhigh-grade vesicoureteral reflux. Conclusions: This study revealed fever>38.2oC and dimercaptosuccinic acid renalscanning as the best predictive markers for vesicoureteral reflux in children with theirfirst febrile urinary tract infection. In addition, erythrocyte sedimentation rate, positiveurinary nitrite test, hyaline cast, and renal ultrasound are the best predictivemarkers for high-grade vesicoureteral reflux.

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