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부유대역 용융응고법으로 제조된 YBa_2Cu_3O_x 산화물초전도체의 미세구조와 전기적 특성
노태형,송정환,장규철,한이섭,김소정,구본급,김호기 대전산업대학교 반도체기술연구소 2000 半導體技術硏究所報 Vol.2 No.-
The YBa_2Cu_3O_x-20 wt% Y_2BaCuO_5 composition designed in YBCO system was synthesized by solid state reaction method. The optimum condition of hot zone temperature and growth rate in floating-zone melt were 1080 ℃ and 2.5 mm/hour, respectively. In samples growth as these condition, the low angel boundaries in grain direction and small amount of amorphous phase known as decreasing characteristics of superconducting materials between grain boundaries in microstructure are investigated by polarized light microscopy on the whole. The critical current density(Jc) at 77k of sample using powder fabricated with no CeO_2 and doped 5 wt%CeO_2 were 8,000 A/㎠(Jc : 561A) and 12,000 A/㎠(Jc: 826A) at 0 T by direct current transport method, respectively.
Amplification of Sulforaphane Content in Red Cabbage by Pressure and Temperature Treatments
Koo, Song-Yi,Cha, Kwang-Hyun,Song, Dae-Geun,Chung, Dong-Hwa,Pan, Cheol-Ho The Korean Society for Applied Biological Chemistr 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.2
Red cabbage, a Brassica vegetable, has glucoraphanin that is hydrolyzed by myrosinase to form sulforaphane, which has received attention due to its cancer chemopreventive activity. High hydrostatic pressure (HHP) treatment (100~400MPa) and subsequent incubation ($20{\sim}80^{\circ}C$) were employed to amplify health beneficial sulforaphane content in red cabbage. The highest quantity of sulforaphane was $99.7{\mu}mol/kg$ fresh weight from HHP treatment at 400MPa, followed by standing at $60^{\circ}C$. Cytotoxicity was determined to evaluate the side effect of HHP-treated red cabbage.
Amplification of Sulforaphane Content in Red Cabbage by Pressure and Temperature Treatments
( Song Yi Koo ),( Kwang Hyun Cha ),( Dae Geun Song ),( Dong Hwa Chung ),( Cheol Ho Pan ) 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.2
Red cabbage, a Brassica vegetable, has glucoraphanin that is hydrolyzed by myrosinase to form sulforaphane, which has received attention due to its cancer chemopreventive activity. High hydrostatic pressure (HHP) treatment (100~400MPa) and subsequent incubation (20~80℃) were employed to amplify health beneficial sulforaphane content in red cabbage. The highest quantity of sulforaphane was 99.7 μmol/kg fresh weight from HHP treatment at 400MPa, followed by standing at 60℃. Cytotoxicity was determined to evaluate the side effect of HHP-treated red cabbage.
Amplification of Sulforaphane Content in Red Cabbage by Pressure and Temperature Treatments
Song Yi Koo,Kwang Hyun Cha,Dae-Geun Song,Donghwa Chung,Cheol-Ho Pan 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.2
Red cabbage, a Brassica vegetable, has glucoraphanin that is hydrolyzed by myrosinase to form sulforaphane, which has received attention due to its cancer chemopreventive activity. High hydrostatic pressure (HHP) treatment (100~400MPa) and subsequent incubation (20~80oC) were employed to amplify health beneficial sulforaphane content in red cabbage. The highest quantity of sulforaphane was 99.7 μmol/kg fresh weight from HHP treatment at 400MPa, followed by standing at 60oC. Cytotoxicity was determined to evaluate the side effect of HHP-treated red cabbage.
Koo, Song Yi,Cha, Kwang Hyun,Song, Dae-Geun,Lee, Dong-Un,Pan, Cheol-Ho The Korean Society for Applied Biological Chemistr 2012 Applied Biological Chemistry (Appl Biol Chem) Vol.55 No.5
High hydrostatic pressure (HHP) treatment was used to increase the concentration of sulforaphane in Brussels sprout, a cruciferous vegetable known to have health benefits. The highest concentration of sulforaphane was $1021.8{\mu}mol$ per kg fresh weight of Brussels sprouts after HHP treatment at 500 MPa, which corresponded to a 317% increase compared to the HHP-untreated control.
Koo, Song Yi,Mok, Il-Kyoon,Pan, Cheol-Ho,Kim, Sang Min American Chemical Society 2016 Journal of agricultural and food chemistry Vol.64 No.49
<P>To facilitate the utilization of fucoxanthin (FX), a valuable marine carotenoid, in the food industry, FX-loaded casein nanoparticles (FX-CN) and chitosan-coated FX-CN (FX-CS-CN) were developed using the FX-enriched fraction from Phaeodactylum tricornutum. Two nanoscale particles (237 +/- 13 nm for FX-CN and 277 +/- 26 nm for FX-CN-CN) with spherical and smooth surfaces showed over 71% encapsulation efficiency and polydispersity index (PDI) value of 0.31-0.39 in water. Owing to the chitosan coating, FX-CS-CN showed a positive zeta potential (24.00 mV), whereas that of FX-CN was negative (-12.87 mV). In vitro simulated digestion demonstrated better FX bioaccessibility from the nanoparticles versus P. tricornutum powder (Pt-powder) and from FX-CN versus FX-CS-CN. However, in C57BL/6 mice, fucoxanthinol absorption to the blood circulation was two times higher for FX-CS-CN versus FX-CN, possibly due to increased retention or adsorption to mucin by the cationic biopolymer in the chitosan-coated particles. These results demonstrate that FX-CS-CN can enable the application of FX, with improved bioavailability and water dispersibility, in the food industry.</P>
A Novel Type of Spin Injection Barrier in a GaAs Based Two-Dimensional Electron Gas System
Koo, H.C.,Yi, H.,Song, J.D.,Ko, J.B.,Chang, J.,Han, S.H. IEEE 2005 IEEE transactions on magnetics Vol.41 No.10
A low transmission barrier is a crucial factor for the efficient spin injection, and an oxide barrier is commonly used for the insulator between the ferromagnet and the semiconductor. After heat treatment at the furnace, an AlAs layer was converted to an aluminum oxide layer, and arsenic gas was evaporated. This new method of forming spin injection barrier on the two-dimensional electron gas (2-DEG) system is very efficient to obtain tunneling behavior.
Reproductive outcomes of retransferring retained embryos in blastocyst transfer cycles
Yi, Hyun Jeong,Koo, Hwa Seon,Cha, Sun Hwa,Kim, Hye Ok,Park, Chan Woo,Song, In Ok The Korean Society for Reproductive Medicine 2016 Clinical and Experimental Reproductive Medicine Vol.43 No.2
Objective: To determine the incidence of embryo retention (ER) in the transfer catheter following embryo transfer (ET) in blastocyst transfer and investigate whether retransferring retained embryos has an impact on reproductive outcomes in patients undergoing in vitro fertilization-ET. Methods: We retrospectively analyzed the records of 1,131 blastocyst transfers, which comprised 223 single blastocyst transfer (SBT) and 908 double blastocyst transfer (DBT) cycles. Each SBT and DBT group was classified depending on whether ET was performed without retained embryos in the catheter during the first attempt (without-ER group) or whether any retained embryos were found following ET (ER group) for the purpose of comparing reproductive outcomes in a homogenous population. Results: The overall incidence of finding retained embryos was 2.8% (32/1,131). There were no retained embryos in SBT cycles. In DBT cycles, implantation rates (30.0% vs. 26.6%), positive ${\beta}-hCG$ rates (57.2% vs. 56.2%), clinical pregnancy rates (45.3% vs. 46.9%), and live birth rates (38.9% vs. 43.8%) were not significantly different between the without-ER and ER groups. There were no significant differences in the mean birth weight (g) $2,928.4{\pm}631.8$ vs. $2,948.7{\pm}497.8$ and the mean gestational age at birth ($269.3{\pm}17.2days$ vs. $264.2{\pm}25.7days$). A total of nine cases of congenital birth defects were found in this study population. Eight were observed in the without-ER group and one in the ER group. Conclusion: Our results suggest that retransfer of retained embryos does not have any adverse impact on reproductive outcomes in blastocyst transfer cycles. Furthermore, our results support finding that SBT might be advantageous for decreasing the incidence of retained embryos in catheters.
Koo, Ja Seong,Lee, Song Yi,Azad, Md Obyedul Kalam,Kim, Minju,Hwang, Sung Jun,Nam, Suyeong,Kim, Sungyun,Chae, Byung-Jo,Kang, Wie-Soo,Cho, Hyun-Jong Elsevier 2019 International journal of pharmaceutics Vol.558 No.-
<P><B>Abstract</B></P> <P>Particle size reduction of FeSO<SUB>4</SUB> (iron(II) sulfate, IS) from micron to nano size was achieved by a combination of hot-melt extrusion (HME) processing and the input of Span 80, Tween 80, and poly(ethylene glycol) (PEG) 6000. Conveying, kneading, and extruding steps of the HME process and a decrease in the surface tension by surfactants were introduced to produce FeSO<SUB>4</SUB> nanoparticles (NPs) in an aqueous environment. The FeSO<SUB>4</SUB>-based NPs (ISNPs) in the dispersion were composed of FeSO<SUB>4</SUB>, Span 80, Tween 80, and PEG 6000 and displayed a hydrodynamic size of 350–400 nm (5–50 mg/mL ISNPs concentration range) and a spherical shape. Considering the feeding ratio of FeSO<SUB>4</SUB> (20%, w/w) used for preparing the ISNPs, FeSO<SUB>4</SUB> appears to be wrapped by Span 80, Tween 80, and PEG 6000 according to the results of X-ray photoelectron spectroscopy (XPS) analysis. ISNPs exhibited different thermodynamic properties from those of FeSO<SUB>4</SUB> itself. In colon adenocarcinoma (Caco-2) cells, the ISNPs group exhibited enhanced antiproliferation and apoptosis potentials compared to the FeSO<SUB>4</SUB> group (<I>p</I> < 0.05). Histological staining data of a dissected intestine after oral administration of ISNPs suggest the absence of severe intestinal toxicities compared to the control (no treatment) group. All of these results imply the feasibility of the use of the developed ISNPs for the treatment of colon cancers with oral administration.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>