CGRP,SP의 국소도포와 전기자극에 의한 고양이 치수신경활동의 변화

손호현,김미자 大韓齒科保存學會 1995 Restorative Dentistry & Endodontics Vol.20 No.2

복합레진 수복 시 재접착 술식이 미세누출에 미치는 영향

이미애,서덕규,손호현,조병훈 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.3

복합레진 수복시, 일반적으로 연마, 산부식, 수세 및 건조 단계를 거쳐 저점도 레진을 적용하는 재접착 술식을 통해 예상되는 수축간극을 봉쇄한다. 그러나, 이 과정은 재접착제 적용 이전에 물이나 잔사가 간극을 매워버릴 수 있어 그 효과가 의심된다. 본 실험에서는 연마 단계 이전, 즉 복합레진을 중합한 직후에 재접착제를 도포한다면 변연누출을 더 줄일 수 있을 것이라는 가설을 검증하고자 하였다. 실험을 위해 35개의 발거한 대구치에서 협면과 설면에 교합면 변연은 법랑질에, 치은측 변연은 상아질에 위치하는 5급 와동을 형성하였다. 와동은 Z250 (3M ESPE, USA)로 충전하였고, 접착제로는 AdperTM Single Bond 2(3M ESPE)을 사용하였다. 재접착제로는 Biscover LV (Bisco, USA) 레진 전색제와 ScotchBond Multi-purpose system(3M ESPE)의 접착제, 및 점도가 낮은 실험용 접착제를 연마 전 또는 일련의 연마 및 산부식 후 수복물의 변연에 적용하였다. 2% 메틸렌 블루 용액에 네 시간 동안 침적한 뒤 교합측 및 치은측 변연에서의 색소 침투 깊이를 광학 입체 현미경으로 측정하였다. 재접착제의 점도와 변연미세누출의 상관관계도 평가하였다. 재접착 술식, 재접착제, 및 변연의 위치, 그 각각에서는 통계적으로 유의한 차이를 관찰할 수 없었다. 그러나, 재접착 술식을 시행하지 않은 대조군의 경우에는 세 가지 재접착제를 사용한 재접착군에 비해 치은측 변연에서 미세누출이 통계적으로 유의하게 크게 나타났다(p < 0.05). 대조군과 재접착군의 미세누출의 차이는 교합측 변연에서는 관찰되지 않았다. 연마 및 산부식 후 치은변연에 재접착제를 적용한 경우에서 약한 음의 상관관계(r = -0.326, p = 0.041)를 보인 경우를 제외하고는, 재접착제의 점도와 미세누출은 유의한 상관관계를 보이지 않았다. During a composite resin restoration, an anticipating contraction gap is usually tried to seal with low-viscosity resin after successive polishing, etching, rinsing and drying steps, which as a whole is called rebonding procedure. However, the gap might already have been filled with water or debris before applying the sealing resin. We hypothesized that microleakage would decrease if the rebonding agent was applied before the polishing step, i.e., immediately after curing composite resin. On the buccal and lingual surfaces of 35 extracted human molar teeth, class V cavities were prepared withthe occlusal margin in enamel and the gingival margin in dentin. They were restored with a hybrid composite resin Z250 (3M ESPE, USA) using an adhesive AdperTM Single Bond 2 (3M ESPE). As rebonding agents, BisCover LV (Bisco, USA), ScotchBond Multi-Purpose adhesive (3M ESPE) and an experimental adhesive were applied on the restoration margins before polishing step or after successive polishing and etching steps. The infiltration depth of 2% methylene blue into the margin was measured using an optical stereomicroscope. The correlation between viscosity of rebonding agents and mciroleakage was also evaluated. There were no statistically significant differences in the microleakage within the rebonding procedures, within the rebonding agents, and within the margins. However, when the restorations were not rebonded, the microleakage at gingival margin was significantly higher than those groups rebonded with 3 agents (p < 0.05). The difference was not observed at the occlusal margin. No significant correlation was found between viscosity of rebonding agents and microleakage, except very weak correlation in case of rebonding after polishing and etching at gingival margin (r = -0.326, p = 0.041).

골격성 Ⅲ 급 부정교합자의 두개안모 성장예측에 대한 평가

손우성,강은희,정미라,성지현 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.1

본 연구는 성장에 의한 변화를 예측하는 현재의 방법이 실제로 골격성 Ⅲ급 부정교합자의 진단과 치료계획에 적절히 사용될 수 있는 지를 판단해 보기 위해 초진 시 골격성 Ⅲ급 부정교합으로 진단받고 성장 종료 후 악교정 수술을 받기위해 재내원한 골격성 Ⅲ 급 부정교합자 25명(남자 13명, 여자 12명)을 대상으로 시행되었다. 초진시 채득된 측모 두부방사선 사진에서 Ricketts의 성장예측법을 통해 성장 종료 후의 상태를 예측한 후, 악교정 수술을 위해 재내원 했을 때 채득된 측모 두부방사선 사진에서 계측된 실제 성장량과 비교분석 함으로써 다음과 같은 결론을 얻었다. 1. 예측치와 관측치의 일치정도를 평가해본 결과 Porion Location, Ramus Position, Facial Depth, Facial Axis, Mandibular Plane angle, Maxillary Convexity에서의 예측치가 관측치와 차이를 보이고 있어 이 항목에 대한 Ricketts 성장예측법의 예측치가 실제 성장량을 잘 설명해주지 못함이 관찰되었다. 2. 하악골체의 성장량은 정상 성장량과 유사하였으나 Porion Location, Ramus Position이 정상적인 성장과정을 벗어나면서 하악골의 전방위치를 유도하였다. 3. 골격성 Ⅲ 급 부정교합자에서는 성장의 양과 방향이 비정상적인 성장변화를 나타내어 정상 성장에서라면 변화를 보이지 않을 하악지의 전방 위치, 하악이부의 전상방 회전 등이 일어난 하악 전돌의 경향이 악화될 수 있다. This study was performed to evaluate whether growth prediction method can be used to diagnose and make treatment plan in skeletal Class Ⅲ malocclusion patients or not. The sample was consisted of 25 patients(13 males, 12 females) who had been diagnosed with skeletal Class Ⅲ malocclusion at first visit and after that had returned to take orthognathic surgery. Growth prediction performed with Ricketts' growth prediction method from first cephalogram was compared with actual growth of the second cephalogram. The findings of this study were as follows ; 1. There was significant difference between actual growth and growth prediction in Porion Location, Ramus Position, Facial Depth, Facial Axis, Mandibular Plane angle, Maxillary Convexity. So, for these items Ricketts' growth prediction method is not proper to predict growth. 2. Although the growth amount of mandibular body was similar to normal growth amount, mandible was positioned anteriorly because of Porion Location and Ramus Position. 3. In skeletal Class Ⅲ malocclusion patients, the tendency of mandibular prognathism might be aggreviated because of anterior placement of ramus and anterosuperior rotation of pogonion.

수용성 및 지용성 피부투과증진제의 피부의 전기적 성질에 미치는 영향

손미현,오승열 숙명여자대학교 약학연구소 2005 약학논문집-숙명여자대학교 Vol.22 No.-

무모생쥐 피부의 전기적 임피던스를 교류 주파수의 함수로 측정 한 후 Nyquist plot을 이용하여 전기적 저항 및 축전력을 계산하였으며 이 방법에 의해 수용성 (프로필렌 글리콜 및 에탄올) 및 지용성 (propylene glycol monolaurate, isopropyl mirystate) 투과증진제가 피부의 전기적 성질에 미치는 영향을 연구하였다. 피부에 각투과증진제를 적용하여 1시간동안 neat 처리를 한후시간에 따른 전기저항 및축전력의 변화를 8시간 동안조사하였다.수용성 투과증진제의 경우 neat 처리 후 바로측정하였을때 전기저항이 감소하였으나시간에 따라 점차 회복하였으며 축전력도 점차 증가하였다. 이 같은 전기저항의 증가는 피부 내로 투과되었던 수용성 투과증진제들이 용액으로 다시 용출되어 나오는 것에 기인된다고 사료된다.지용성 투과증진제의 경우전기저항은크게 감소하였고 축전력은 크게 증가하였다. 그러나 수용성 투과증진제의 경우에서와 같은 시간에 따른 큰 변화는 관찰되지 않았는데 이는 이틀 지용성 투과증진제의 경우 일단 피부 각질층 내로 투과된 후 시간에 따라 각질층 밖으로 역확산되어 나오지 않기 때문이라고 생각된다. 축전력의 증가는 각질층 내의 지질의 질서도감소에 의한유전상수의 증가때문으로사료되며 이상의 결과는 각질층이 피부의 전기적 성절에 미치는 역할에 대한 기초적인 자료를 제공하고 있다.

초등교사의 체육수업운영에 관한 진단과 대안

손준구,현미용 부산교육대학교 교육대학원 1999 논문집 Vol.1 No.-

The purpose of this study was to make improve elementary school teacher(EST)s' managerial skills in school physical education classes. The subjects of instruction were 24 EST(female and male 12 each other). The subjects of group interview were 6 EST(female and male 3 each other). Applied variables in this study were instruction readiness, waiting, and transition. These variables were excerpt from Son(1997)' KNUSⅡ(Kyungpook National University SystemⅡ). According to the results, EST were spended 3.5% for instruction readiness, 2.3% for waiting, and 11.5% for transition in physical education classes. EST presented the substantiality on materials researches, the enthusiasm on physical education classes, the induction of specialist system, and the improvement of instructional environment in grouping interview. The purpose of physical education is to provide more learning time for students in order to increase the amount of content covered. Therefore, EST may well be make efforts to get effective management skills in their instruction. But such effects of EST must run parallel with the improvement of instructional environment.

구치부 2급와동에 있어 심미성 수복물의 변연접합도에 관한 연구

유미경,이광원,손호현 全北大學校 齒醫學硏究所 1993 전북치대논문집 Vol.11 No.1

The purpose of this study was to evaluate the cervical marginal adaptation of direst composite resin, composite resin, composite resin inlay and porcelain inlay technique. 40 cavities of class Ⅱ were prepared 40 extracted maxillary premolr teeth, which were divided into four groups. Group 1 : restored by direct filling method(P50) Group 2 : restored by direct filling method(Z100) Group 3 : restored by resin inlay method(Estilux posterior CVS) Group 4 : restored by procelain inlay method(Vita-dur N) All the specimens were embedded into stainless steel mold after thermocycling between 5℃ and 55℃. Phototaking under microscopic image and measuring the marginal gap on the photographs and statistical analysis were peformed Specimens from each group were cut mesio-distally and observed under SEM. The results were as follows : 1. The groups restored by inlay method showed significantly less marginal gap than groups restored by direct filling method(P<0.05). 2. There was no significant difference in marginal gap between composite resin inlay group with porcelain inlay group(P>0.05). 3. The group restored by direct filling method(Z100) showed significantly less marginal gap than group restored by direct filling method(P5O)(P<0.05). 4. SEM examination indicated that direct composite resin groups were larger gaps(10- l5μm) than groups(2-5μm).

임신부의 인플루엔자 백신 접종률 및 관련요인

김미정,이승연,이광수,김아름,손동욱,정문현,박신구,박지현,이병익,이진수 대한감염학회 2009 감염과 화학요법 Vol.41 No.6

Background : During seasonal influenza epidemics and previous pandemics, pregnant women have been at increased risk for complications related to influenza infection. Although influenza vaccination has been widely recommended to pregnant women and immunocompromised hosts, the vaccination rate is presumed to be low in pregnant women. This study was aimed to evaluate the vaccination rate and factors associated with Influenza vaccination among pregnant women, who are at high risk for developing complications from the influenza. Materials and Methods : This study was carried out by telephone survey from April, 2007 to August, 2007. Women who were in their second trimester of pregnancy or above,- during October, 2006 and February, 2007, the recommended vaccination period, and had given birth at Inha University Hospital were selected as the study population. Immunization status, general understanding, and factors associated with vaccination were evaluated. Results : Among a total of 506 eligible pregnant women, 227 (44.8%) responded to the questionnaires. The influenza vaccination rate among the pregnant women was only 4% (9/227). Major reasons for not receiving vaccination were first, not awaring the necessity of immunization during pregnancy (48.5%, 110/227) and second, misunderstanding that it is prohibited during pregnancy (36.1%, 82/227). The major factors that influenced the compliance of vaccination were correct understanding and doctor's recommendation on the influenza immunization during pregnancy. Conclusions : The influenza vaccine coverage on pregnant women was very low and the awareness of influenza vaccination during pregnancy in general was inaccurate. Shift in perception is required and this can be achieved by educating the pregnant women on the safety and efficacy of vaccination. In addition, doctors' active encouragement to vaccination is highly recommended.

간호사의 임상 실무 경험

서문자,손행미,강현숙,권성복,김주현,박영숙,이은희,임난영,조경숙,지성애 성인간호학회 2002 성인간호학회지 Vol.14 No.4

purpose: This study was conducted to describe qualitatively the entities of nurse's experiences in general hospitals and to suggest basic data guiding research on developing Standards of clinical nursing practice in Korea. Method: Fourteen nurses working at general hospitals with over 300 beds in Seoul were interviewed in-depth until saturation using tape-recorders and transcription. Result: The central theme of clinical nursing practice experienced by subjects was "being with clients" that means accepting client's personal character, solving client's needs and providing client-centered nursing. A also "being with clients" was felt to be the responsibility of nurses which was learned from their nursing schools. The nursing strategies performed in order to be with patients were proving skillful nursing techniques, accepting, educating, emotional support, advocating, and self-reflecting, the subjects experienced somewhat problematic affects such as difficulties in interpersonal relationship, work overload, negative image of nursing, deficit of self-confidence for nursing actions, poor working conditions, and unfair treatment. Nurses at the hospital practiced with pride when they felt that they were accepted by clients. Conclusion: Further research is needed to analysis problems in clinical practice and the comparison of nurses' experiences of clinical practice, with nurses' experiences in various settings.

상아질 접착제가 상아질 변연누출에 미치는 영향

채수경,김미자,이광원,손호현 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

The purpose of this study was to evaluate the effect of various dentin adhesives on the incisal and gingival marginal leakage of class Ⅴ cavity. V-shape cavities with enamel bevel (0.7-1㎜) were prepared on the faciocervical area of 72 extracted human anterior teeth. Gingival margin of cavities was placed on dentin or cementum. Including 1 group with no dentin treatment, they were divided into 6 groups according to dentin surface treatment with Scotchprep(3M Co.), Prisma Universal Bond 2(Dentsply Inter. Inc.), Gluma(Cloumbus/Bayer), All BOND 2(Bisco inc.) and Denthesive(Kulzer Co.). After dentin treatment, Dentin adhesive(3M Co.) was applied on the treated dentin surface and Silux("U" shade, 3M Co.) was filled and polished. Dye penetration technique using 2% methylene blue solution was adopted to assess incisal and gingival marginal leakage. The following results were obtained 1. The degree of incisal marginal leakage in the non-treated group was greater than that in other groups(p<0.01), and incisal marginal leakage in the groups treated with All BOND 2, and Denthesive was less than that in the group treated with Gluma(P<0.01). 2. Incisal marginal leakage in the groups treated with Prisma Universal Bond 2, and Scotchprep was less than that in the group treated with Gluma(p<0.01). 3. Incisal marginal leakage among the groups treated with Scotchprep, Prisma Universal Bond 2, All BOND 2 and Denthesive was not different(p>0.05). 4. The degree of gingival marginal leakage in the non-treated group was significantly greater than that in other groups(p<0.01). 5. Gingival marginal leakage among the groups treated with Scotchprep, Prisma Universal Bond 2, Gluma, All BOND 2, and Denthesive was not statistically significant(p>0.05). But gingival marginal leakage was significantly less in the All BOND 2 treated group compared with Gluma treated group(p<0.05).

폐렴 구균(Streptococcus pneumoniae)에 의한 척수 경막외 농양 1예

이지영,위유미,손경목,기현균,문치숙,오원섭,백경란,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

폐렴구균은 보통 폐렴이나 뇌막염을 일으키는 균으로 척수 경막외 농양을 일으키는 경우는 매우 드물다. 본 저자들은 폐렴 구균에 의한 척수 경막 외 농양을 경험하여 보고하는 바이다. 과거 건강했던 36세 남자 환자로 사다리에서 낙상한 후 요통 및 고열, 신경학적 이상으로 내원하여 자기 공명 촬영 결과 척수 경막 외 농양으로 진단받고 항균제 투여와 함께 응급 수술을 시행하였다. 농 배양 결과 페니실린 감수성인 폐렴 구균이 분리 되었고, 수술 요법과 항생제 투여 후 농양은 치유되었으나 신경학적 이상은 호전 없는 상태로 타원으로 전원되었다. Pneumonia and meningitis are the most frequent manifestations of pneumococcal infections. Pneumococcal spinal epidural abscesses have been rarely reported. Spinal epidural abscess by Streptococcus pneumoniae has been diagnosed among the patients with diabetes mellitus, alcoholism, corticosteroid therapy, intravenous drug use, chronic renal failure, AIDS, and history of spinal surgery. Recently, we experienced a case of pneumococcal spinal epidural abscess after spinal trauma. A 36-year-old male patient was admitted with back pain, fever, and paraplegia which occurred 5 days after the trauma. Spine MRI revealed spinal epidural abscess at the level from T2 to T9. He was treated with antimicrobial agents and surgical exploration for spinal epidural abscess. Pus culture grew S. pneumoniae which was susceptible to penicillin. Despite early surgical treatment, neurologic sequelae remained. Considering the high mortality and morbidity of pneumococcal spinal epidural abscess, early diagnosis and aggressive treatment including surgical intervention and antibiotics therapy should be implemented immediately.