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      • Accelerated cardiac <i>T</i><sub>2</sub> mapping using breath‐hold multiecho fast spin‐echo pulse sequence with <i>k‐t</i> FOCUSS

        Feng, Li,Otazo, Ricardo,Jung, Hong,Jensen, Jens H.,Ye, Jong C.,Sodickson, Daniel K.,Kim, Daniel Wiley Subscription Services, Inc., A Wiley Company 2011 Magnetic resonance in medicine Vol.65 No.6

        <P><B>Abstract</B></P><P>Cardiac <I>T</I><SUB>2</SUB> mapping is a promising method for quantitative assessment of myocardial edema and iron overload. We have developed a new multiecho fast spin echo (ME‐FSE) pulse sequence for breath‐hold <I>T</I><SUB>2</SUB> mapping with acceptable spatial resolution. We propose to further accelerate this new ME‐FSE pulse sequence using <I>k</I>‐<I>t</I> focal underdetermined system solver adapted with a framework that uses both compressed sensing and parallel imaging (e.g., sensitivity encoding) to achieve higher spatial resolution. We imaged 12 control subjects in midventricular short‐axis planes and compared the accuracy of <I>T</I><SUB>2</SUB> measurements obtained using ME‐FSE with generalized autocalibrating partially parallel acquisitions and ME‐FSE with <I>k</I>‐<I>t</I> focal underdetermined system solver. For image reconstruction, we used a bootstrapping two‐step approach, where in the first step fast Fourier transform was used as the sparsifying transform and in the final step principal component analysis was used as the sparsifying transform. When compared with <I>T</I><SUB>2</SUB> measurements obtained using generalized autocalibrating partially parallel acquisitions, <I>T</I><SUB>2</SUB> measurements obtained using <I>k</I>‐<I>t</I> focal underdetermined system solver were in excellent agreement (mean difference = 0.04 msec; upper/lower 95% limits of agreement were 2.26/−2.19 msec, respectively). The proposed accelerated ME‐FSE pulse sequence with <I>k</I>‐<I>t</I> focal underdetermined system solver is a promising investigational method for rapid <I>T</I><SUB>2</SUB> measurement of the heart with relatively high spatial resolution (1.7 × 1.7 mm<SUP>2</SUP>). Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc.</P>

      • KCI등재후보

        Towards Routine Clinical Use of Radial Stack-of-Stars 3D Gradient-Echo Sequences for Reducing Motion Sensitivity

        Block, Kai Tobias,Chandarana, Hersh,Milla, Sarah,Bruno, Mary,Mulholland, Tom,Fatterpekar, Girish,Hagiwara, Mari,Grimm, Robert,Geppert, Christian,Kiefer, Berthold,Sodickson, Daniel K. Korean Society of Magnetic Resonance in Medicine 2014 Investigative Magnetic Resonance Imaging Vol.18 No.2

        Purpose : To describe how a robust implementation of a radial 3D gradient-echo sequence with stack-of-stars sampling can be achieved, to review the imaging properties of radial acquisitions, and to share the experience from more than 5000 clinical patient scans. Materials and Methods: A radial stack-of-stars sequence was implemented and installed on 9 clinical MR systems operating at 1.5 and 3 Tesla. Protocols were designed for various applications in which motion artifacts frequently pose a problem with conventional Cartesian techniques. Radial scans were added to routine examinations without selection of specific patient cohorts. Results: Radial acquisitions show significantly lower sensitivity to motion and allow examinations during free breathing. Elimination of breath-holding reduces failure rates for non-compliant patients and enables imaging at higher resolution. Residual artifacts appear as streaks, which are easy to identify and rarely obscure diagnostic information. The improved robustness comes at the expense of longer scan durations, the requirement for fat suppression, and the nonexistence of a time-to-center value. Care needs to be taken during the configuration of receive coils. Conclusion: Routine clinical use of radial stack-of-stars sequences is feasible with current MR systems and may serve as substitute for conventional fat-suppressed T1-weighted protocols in applications where motion is likely to degrade the image quality.

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