오공약침의 안전성에 대한 임상적 연구

소기숙,최회강,박소영,고강훈,김성남,이옥자,윤민영,문형철,김성철,이정훈,나원경,So, Ki-suk,Choi, Hoi-kang,Park, So-young,Koh, Kang-hun,Kim, Sung-nam,Lee, Ok-ja,Yun, Min-young,Mun, Hyung-chul,Kim, Sung-chul,Lee, Jung-hun,Na, Won-kyung 대한침구의학회 2004 대한침구의학회지 Vol.21 No.1

Objective: Recently scolopendrid aquacupuncture has been a good effect on pain control but it has not been known about clinical safety. So, In order to prove the clinical safety of scolopendrid aquacupuncture, We have observed the physical reac-tion and clinical pathology test after scolopendrid aquacupuncture treatment. Methods: We analyzed physical reaction and clinical pathology test before and after Scolopendrid aquacupuncture treatment of 30 patients suffering from pain, who admitted department of Acupunture and Moxibustion, College of Oriental Medicine, Won-Kwang University Kwangju hospital. Results & Conclusions: The results were summarized as follows. 1) The distribution of sex was 14 males and 16 females, and the average of patients age was 46.2 years. 2) The distribution of symptom was lumbago, lumbago with radiating pain, nuchal pain and knee joint pain. 3) In the 30 patients treated with Scolopendrid aquacupuncture, hematologic test did not show remarkable change. 4) In the 30 patients treated with Scolopendrid aquacupuncture, Liver function test(AST, ALT, ALP) showed a slight decrease on the contrary, and abnormal rate showed a decrease of 1.0%(from 3.3% to 2.3%) compared with previous study. 5) In the 30 patients treated with Scolopendrid aquacupuncture, Renal function test(BUN, Cr) and abnormal rate(from 2.5% to 2.0%) showed a slight decrease on the contrary. 6) In the 30 patients treated with Scolopendrid aquacupuncture. Electrolyte were normal range before & after treatment. 7) In the results of the Urine analysis of 30 patients, Leukocyte, Protein. Glucose, Keton, Bilirubin, U-bilinogen were not detected before and after Scolopendrid aquacupuncture treatment, and the rest almost made no difference. 8) In the Physical reactions, all of the patients complained of pain of body partially, only one patient showed reddish and itch, but symptoms like those were entirely disappeared within 24 hours and whole body pain, swelling, headache, dizziness, fatigue and nausea was not observed.

地域社會開發運動에 있어서 새마을 運動의 本質및 그成果와 問題點에 關한 考察

蘇鎭雲,丁相賢 群山大學校 1984 論文集 Vol.8 No.-

In this paper we considered its performance and issue, including essence of Saemaul Undong drived forward as the community development movement. By the way, we can regard the community development movement as one appeared according to social demands to promote the state development and introduce change. Such a movement can be attempted as the true development of the state when organic connection is attained well together with the financial support of government and its continuous endeavor support through the activities of education and public relations as well as the voluntary and positive participation of inhabitants lied scattered in community, not by achievement-displayed, uniform, one-sided effort of government in country which various given condition, economical, social, cultural is put on developing situation, and especially if we should put political purpose on the place being in harmony with the conviction, activity and goal of inhabitants when participation of them with the character of mobilization, participation in a involuntary gathering, and so forth is corrected without a day's delay. Accordingly we think that the unfolding of the community development movement which looks upon the voluntary effort and participation of inhabitants as its essential elements becomes its base in the pursuit of the state development. Therefore, I think we can obtain desirable performance when we put the big specific gravity on such a enterprise of community development from now on in the Saemaul Undong drived forward up to now as the community development movement in our country which looks upon the self-reliance and the prosperity as its goal.

전립선 선암종에서의 p53 및 I-cadherin 단백의 면역조직 화학적 연구

맹이소,김원일,이교영,김영신,강창석,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.3

인접한 블록의 움직임 벡터의 방향성을 이용한 고속 움직임 추정 알고리즘

소현호,김진상,조원경 경희-다반 ASIC 설계교육센터 2003 경희-다반 ASIC센터 논문집 Vol.4 No.-

본 논문에서는 현재 블록의 이웃한 블록들의 움직임 벡터(motion vector, MV)와 움직임 벡터들의 방향성을 고려하여 현재 블록의 움직임 벡터를 예측하여 후보 블록의 개수를 줄여 계산 속도를 빠르게 하는 블록 매칭움직임 추정 알고리즘을 제안한다. 제안된 알고리즘은 다이아몬드 패턴(Diamond Search)을 수정하여 방향성과벡터의 크기를 고려하여 패턴의 간격과 방향등을 결정하여 움직임 벡터의 후보들을 결정한다. 제안된 알고리즘은 다른 다양한 검색방법들과 비교하여 더 적은 계산량을 갖으면서 비슷한 성능을 보여준다.

전장용 레진의 색안정성에 대한 연구

박상원,조신석,양홍서 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

In this study, metal specimens were made of semiprecious metal alloy and veneered with composite resin(Dentacolar, Kulzer). Germany, Color stability of each specimen was evaluated by the CIE L*a*b* system. Specimens were divided into 3 groups as follows ; Group 1; Resin with 0.1 mm opaque layer Group 2; Resin with 0.25 mm opaque layer Group 3; Resin with 0.5 mm opaque layer The purpose of this study was to evaluate the color difference and color stability of specimens, following to the opaque thickness. The results obtained were as follows ; 1. The group 1 had best color stability after thermocycling. 2. After thermocycling, the specimens with more than 0.25 mm opaque thickness showed detectable color change and ΔE*ab values were more than 3.3 level. 3. After thermocycling, L* value was decreased and a* value was increased in group 2 and 3.

16S rDNA 클론 library 제작 및 핵산염기서열 결정을 통한 교정용 미니임플랜트 주위 열구의 세균 동정

임성훈,김광원,유소영,국중기,장영일 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.4

교정치료 시 고정원으로 사용되는 교정용 미니임플랜트는 가동성 점막인 치조점막 부위에 식립해야 하는 경우가 많은데, 이때 미니임플랜트 주위 연조직의 증식을 동반한 염증이 빈번히 발생한다. 본 연구에서는 치조점막에 식립하여 연조직 증식이 발생된 미니임플랜트 주위의 세균총과 동일 환자의 인접한 건강한 치은 열구의 세균총을 비교하고자 하였다. 이를 위해 7명의 환자를 대상으로 하악 구치부의 치조점막에 식립하여 연조직 증식이 발생한 미니임플랜트 및 이에 연결된 결찰선 주위 열구의 세균막과 미니임플랜트에 인접한, 치은 염증이 없는 제2대구치의 치은열구의 세균막을 멸균된 paper point로 채취한 후, 16S rDNA 클론 library 제작 및 핵산염기서열 분석법을 이용하여 세균을 동정하여 비교하였다. 실험 결과 미니임플랜트 주위 열구로부터 304개의 16S rDNA 클론을 얻었으며, 치은열구로부터 238개의 16S rDNA 클론을 얻었다. 클론의 9.2%에 해당하는 24종의 세균들은 미니임플랜트 주위 열구에서만 검출되었고, 이들은 Haemophilus aphrophilus, Sphingomonas species, Capnocytophaga species, Prevotella melaninogenica, Lachnospiraceae species, Porphyromonas species, Neisseria flava 등이었다. 전체 클론의 80.4%에 해당하는 29종의 세균들은 미니임플랜트 주위 열구 및 건강한 치은 열구 모두에서 검출되었다. 이들 중 특히 미니임플랜트 주위에서 더 많은 클론이 분리된 세균들은 Prevotella species, Atopobium rimae, Veillonella species, Streptococcus intermedius/constellatus, Streptococcus salivarius 등이었다. 향후 연구에서는 본 연구에서 치조점막에 식립한 미니임플랜트 주위에서 검출된 세균들이 염증을 일으키거나 악화시킬 수 있는지를 밝히는 것이 필요하며, 이를 바탕으로 치조점막에 식립한 미니임플랜트 주위의 연조직 염증을 줄일 수 있는 방법을 찾는 것이 바람직하다. Objective: The purpose of this study was to compare the bacterial flora at the peri-implant sulcus of the orthodontic mini-implant placed in the alveolar mucosa with the bacterial flora at the adjacent healthy gingival sulcus. Methods: Two plaque samples from 7 patients were collected by inserting paper points into the sulcus between the mini-implant and ligature wire connected to the mini-implant head and inflamed alveolar mucosa, and from the gingival sulcus of a healthy tooth adjacent to the mini-implant. Results: Using 16S rDNA clone library, the 24 kinds of bacteria including Haemophilus aphrophilus, Sphingomonas species, Capnocytophaga species, Prevotella melaninogenica, Lachnospiraceae species, Porphyromonas species, Neisseria flava were identified only from the sulcus around the mini-implant. These bacteria constituted only 9.2% of total clones, and the bacteria identified from both the sulcus around mini-implants and the gingival sulcus constituted 80.4% of total clones. Of these bacteria, clones of Prevotella species, Atopobium rimae, Veillonella species, Streptococcus intermedius/constellatus, Streptococcus salivarius were more frequently isolated from the peri-implant sulcus. Conclusion: This study suggests that a broad epidemiological study is needed to find causative bacteria which induce inflammation from the peri-implant sulcus.

신체활동이 암에 미치는 영향 : 대장암, 유방암, 전립선암에 대한 역학(疫學)연구를 중심으로

이상원,김연수 서울대학교 스포츠과학연구소 2007 스포츠과학리뷰 Vol.1 No.1

Many efforts have been carried out to cure and treat cancer, but there are still a constant increase in death ratio due to cancer. The prevention of cancer is the most important thing because cancer is the fatal disease. There are many ways to prevent cancer, physical activity is one of them. Many studies have investigated the relationship between physical activity and cancer. The results of these studies are as follows; there is around 40-50% less chance of getting colon cancer, 30-40% for breast cancer, and 10-30% for prostate cancer. Even with all these studies it was hard to find Korean studies investigated the relationship between physical activity and cancer. The prevalence rates of cancer are hugely variable due to the difference of gender, ethics, diet habit and physical activity. So it is needed that studies should be done for each ethical group. The variation of physical activity is huge and it depends on many various factors: intensity, frequency, duration, and type. For this reason, it is hard to estimate the total physical activity accurately with large population in a long term study. The inconsistent results could be attributed, in part, to methodological issues, including crude assessment of physical activity. Therefore further studies should be performed to develope more precise methods of estimating total physical activity and investigate the relationship between physical activity and cancer for reducing cancer with Koreans.

녹차 및 결명자 추출물의 교정용 브라켓과 치면 사이의 경계부에서 분리된 mutans streptococci에 대한 항균작용

임성훈,서정순,윤영주,김광원,유소영,김화숙,국중기,이병래,차종희,박재윤 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.5

본 연구는 치아우식증에 관련된 Mutans streptococci 표준균주 및 임상분리 균주의 성장억제를 유도할 수 있는 천연 생약추출물을 검색하기 위하여 실시되었다. 녹차추출물은 CHMC-2032를 사용하였으며, 결명자 추출물은 50% 에탄올을 이용하여 얻었다. 이들 추출물의 Mutans streptococci 표준균주 및 교정환자들에서 브라켓과 치면 사이의 경계부에서 분리된 각각 10 균주씩의 S. mutans 및 S. sobrinus에 대한 최소성장억제농도를 액체배지 희석법으로 구하였다. 그 결과 CHMC-2032의 S. mutans 및 S. sobrinus의 표준 균주, S. sobrinus의 대부분 임상분리 균주에 대한 최소성장억제농도는 5 mg/ml이었다. 그러나 결명자 추출물에 의한 S. mutans 및 S. sobrinus에 대한 세균 성장억제 효과는 미미하였다. 본 연구 결과 치아우식증의 예방적 측면에서 결명자차보다는 녹차를 마시는 것이 유리하며, CHMC-2032를 이용하여 구강양치용액을 제조하여 사용할 경우 교정환자를 포함하여 대부분의 사람에게서 치아우식증 예방 효과가 있으리고 추정된다. Mutans streptococci is the major causative factor in dental caries. Especially, orthodontic patients with fixed appliance are a risk group for dental caries. Because fixed appliances attached on teeth may change the environment of dental plaque, the enamel decalcification or dental caries around the bracket and band is a major side effect of orthodontic treatment. The aim of this study was to search plant extracts that have antimicrobial effect on mutans streptococci. Seed-extract of Casio tora were prepared with ethanol and CHMC-2032, the leaf-extracts from Camellia sinensis extract, was obtained extract, 2 type strains and 20 clinical isolates of mutans streptococci isolated from the interface between orthodontic brackets and tooth surfaces in the orthodontic patients were used in this study. The minimal inhibitory concentration of CHMC-2032 was 5 mg/ml on the S. mutans KCTC 3065, S. sobrinus KCTC 3088, and 8 clinical isolates of S. sobrinus. However, there was no antibacterial effect of seed-extract of C. tora on mutans streptococci. These data suggest that green tea may be more effective than the tea prepared from C. tora in the prevention of enamel decalcification or dental caries around brackets.

Opaque의 두께가 전장용 레진의 색채에 미치는 영향

박상원,조신석,양홍서 대한치과기재학회 1999 대한치과재료학회지 Vol.26 No.3

The purpose of this study was to evaluate the color difference of specimens with the variation of metal type and opaque thickness. Resin veneered specimens with the same color were fabricated and evaluated by the CIE L*a*b* system. Specimens were divided into 4 groups as follows ; Group P1; Resin with precious metal alloy, 0.1 mm opaque layer Group P2; Resin with precious metal alloy, 0.5 mm opaque layer Group B1; Resin with nonprecious metal alloy, 0.1 mm opaque layer Group B2; Resin with nonprecious metal alloy, 0.5 mm opaque layer The results obtained were as follows ; 1. L* value of group P1 was lower than that of group P2. There was no significant differences in a* values among tested group. 2. Opaque thickness did not produce any significant differences of L*, a*, b* value in the resin veneer groups on the base metal. 3. The ΔE*ab value between P1 and P2 was 2.228 which is noticeable, while the color difference between B1 and B2 was slight.

급결제 및 혼화제 종류가 숏크리트 내구성에 미치는 영향에 관한 연구

백신원,권소진,이영수,김의성,신용석 한국안전학회 2003 한국안전학회지 Vol.18 No.3

Concrete and shotcrete should withstand the conditions for which they have been designed, without deterioration, over a period of years. But concrete and shotcrete are being deteriorated according to aging by internal and external causes. Recently, many studies on the durability of concrete have been conducted. But the durability of shotcrete is rarely studied. So, in this study, chloride ion penetration test, freeze and thaw test, neutralization test were conducted to examine the durability characteristics of shotcrete with several accelerator and chemical admixture types. These results indicate that shotcrete with alkali free accelerator and with superplasticizer are durable. Therefore, the present study provides a firm base to make high performance shotcrete.