전통주 주박의 항혈전 활성 평가

김미선(Mi-Sun Kim),이예슬(Ye-Seul Lee),김종식(Jong Sik Kim),신우창(Woo-Chang Shin),손호용(Ho-Yong Sohn) 한국생명과학회 2014 생명과학회지 Vol.24 No.8

전통주 주박을 이용한 고부가가치 식품소재 개발을 위해, 상업적 시설에서 생산된 3종 약주(J-B, J-S, J-Y) 및 2종 탁주(J-H, J-W) 주박의 ethanol 추출물 및 열수 추출물을 조제하고 이들의 혈액응고 저해활성, 혈소판 응집저해 활성 및 인간 적혈구 용혈활성을 평가하였다. 5종 주박의 pH는 3.90~4.29로 유사하였으나, brix는 5.0~27.0으로 다양하게 나타났으며, 수분 및 알코올 함량에서도 시료에 따라 1.8배의 차이를 나타내었다. 주박의 색차와 성분은 첨가된 부재료 및 사용누룩에 좌우되었으며, J-W 주박의 경우 수분함량이 80.3%, brix 13, 알코올 함량 1.8%를 함유하여 다른 주박에 비해 다양한 식품제조에 용이하게 이용 가능하리라 판단되었다. Ethanol 추출효율은 J-H, J-W, J-B, J-S, J-Y의 순, 열수 추출효율은 J-S, J-B, J-W, J-H, J-Y의 순으로 높았으며, 총폴리페놀 및 총플라보노이드함량은 ethanol 추출물 중에서는 J-H, 열수 추출물 중에서는 J-Y 주박에서 가장 높았다. 5종 주박의 10종 추출물은 모두 5 mg/ml 농도까지 인간 적혈구에 대한 용혈활성이 나타나지 않았으며, J-B, J-S, J-Y의 약주 주박의 ethanol 추출물에서 유의적인 혈액응고저해 활성이 나타났으며, J-W 탁주 주박의 열수 추출물에서 thrombin 저해 활성과 J-B, J-S 및 J-H 주박 열수 추출물에서 혈액 응고인자 저해활성을 확인하였다. 혈소판 응집저해 활성평가의 경우 J-W 탁주 주박의 ethanol 및 열수 추출물에서만 아스피린에 필적하는 우수한 활성이 확인되었다. 본 연구결과는 다양한 약주 및 탁주 주박이 항혈전 활성을 가지고 있으며, 주박으로부터 항혈전제 개발이 가능함을 제시하고 있다. In this study, ethanol and hot water extracts of lees from Korean traditional wine (J-B, J-S, J-Y, J-H, and J-W) were prepared, and their effects on blood coagulation, platelet aggregation, and hemolysis of human red blood cells (hRBCs) were investigated to develop functional food ingredients from lees. The pH and brix of the lees ranged from 3.90 to 4.29 and 5.0 to 27.0o, respectively, and there was a huge difference in the water and ethanol content among the lees. The nuruk and additives used affected the color and physicochemical properties of lees. The J-W takju made from only rice and traditional nuruk, which has 13o brix and 1.8% of alcohol, has potential as functional food ingredient. With regard to the extraction yields of lees, higher yields were obtained from J-H, which contains different medicinal plants, in ethanol, followed by J-W, J-B, J-S, and J-Y. Higher extraction yields of lees were obtained from J-S in hot water, followed by J-B, J-W, J-H, and J-Y, respectively. The ethanol extract of J-H and the hot water extract of J-Y had the highest contents of total polyphenol and total flavonoids among the lees extracts. The 10 lees extracts did not show hemolysis activity against hRBCs up to 5 mg/ml. In an anticoagulation activity assay, the ethanol extracts of three yakju lees (J-B, J-S, and J-Y) and the hot water extract of J-W inhibited thrombin activity, whereas the hot water extract of J-B, J-S, and J-H inhibited blood coagulation factors. In an antiplatelet aggregation activity assay, only the J-W takju lees showed significant inhibition activity. Our results suggest that lees from traditional wine had high potential as a novel antithrombosis agent.

수학자 이상설이 소개한 근대자연과학: <식물학(植物學)>

박영민 ( Young Min Park ),김채식 ( Chae Sik Kim ),이상구 ( Sang Gu Lee ),이재화 ( Jae Hwa Lee ) 한국수학교육학회 2011 수학교육논문집 Vol.25 No.2

본 원고는 2004년 과학사학자 박성래 교수가 독립 운동가이자 한국 근대 수학교육의 아버지로 부르기 시작한 보재 이상설(李相卨, 1870-1917)이 자연과학에 기여한 내용을 다루고 있다. 한국수학사학회지 2009년 11월 호에 자세히 소개된 〈數理〉를 쓴 시기를 전후하여, 같은 시기에 이상설이 붓으로 쓴 것으로 여겨지는 〈植物學>(이상설, 1899)은 총 4면의 초록 필사본이며, 그 대본(臺本)은 〈植物學啓蒙〉 (Edkins, 1886)으로 영국의 Joseph Edkins(艾約瑟, 1823-1905)가 번역하여 1886년에 간행한 〈西學啓蒙〉 16종 가운데 하나이다. 이상설의 〈植物學>은 이 〈植物學啓蒙〉을 읽으면서 그 책의 내용 중 당시의 조 선 학자가 모르고 있던 새로운 내용을 중심으로 메모를 한 것으로 여겨진다. 본 연구에서는 전통산학과 근대서양수학을 연결하는 〈數理〉를 저술했으며. 우리나라의 정규 교과과정에 수학과 과학을 필수과목으로 지정하고, 첫 번째 수학교과서 〈산術新書〉를 발간함으로 당대 최고의 수학자로 평가된 이상설이 쓴 〈植物學〉을 발굴하여 그 내용과 의미를 최초로 분석한다, 이를 통하여 당시 조선의 서양 과학, 특히 식물학에 대한 이해 수준을 분석하고 〈植物學〉의 원전인 〈植物學啓蒙〉 과 <西學啓蒙〉의 저자에 대하여 알아본다. 이는 당시 수학교육자가 자연과학분야에 행한 교육적 기여를 이해 하는데 필수적인 연구이다. This paper deals with contents that Sang-Seol Lee contributed to the natural science in the 19th century Korea. Prof. Sung-Rae Park, the science historian, called Sang-Seol Lee Father of the Modern Mathematics education of Korea. Sang-Seol Lee wrote a manuscript Botany with a brush in late 19th century. Botany was transcribed from Science Primers: Botany (written by J. D. Hooker), which is translated into Chinese by Joseph Edkins in 1886. The existence of Sang-Seol Lee`s book Botany was not known to Korean scientists before. In this paper, we study the contents of Botany and its original text. Also we analyze people`s level of understanding Western sciences, especially botany at that time. In addition, we study authors of 16 Primers for Western Knowledge. We study the contribution of mathematician Sang-Seol Lee to science education in the 19th century Korea.

이천석 목사의 부흥운동에 관한 연구

이영식 ( Lee¸ Young Sik ) 아신대학교 신학연구소 2020 ACTS 신학저널 Vol.46 No.-

This paper researches pastor Chun Seok Lee’s revival movement, focusing on the prayer center movement, the repentance movement, the urging for the fulfilling of the Holy Spirit, and healing ministry. In his youth, he lost one leg during taking part in the Korean War. He organized a gang and lived a life of debauchery. However, He met the Lord personally and studied theology. He sought the help of the Holy Spirit while doing the work of the Lord, fasted, prayed all night long. He emphasized prayer and had a great influence on the prayer movement of the Korean church. The practice of his awareness of the importance of prayer is the beginning of Haneolsan Prayer Center. Also, what he emphasized in his sermons was repentance and change. These spiritual activities had influence on the Korean church.He also urged the desire for the fullness of the Holy Spirit and revival. In addition, through him, the miracle of healing appeared powerfully. So numerous sick people were healed and devoted more to their faith, and unbelievers came to the Lord. In the end, it can be concluded that the prayer movement, repentance movement, emphasis on the fullness of the Holy Spirit, and healing activities in pastor Chun Seok Lee’s ministry were revival movement. Today, prayer centers are decreased and the desire for revival is less than in the 1970s in Korea. I want all of us to restore the aspirations for revival in our land again. I think we must share and inherit the spiritual assets of pastor Chun Seok Lee and other advanced believers.

수학자 보재 이상설(李相卨)의 근대자연과학 수용 -『백승호초(百勝胡艸)』를 중심으로-

이상구 ( Sang Gu Lee ),박종윤 ( Chong Yun Park ),김채식 ( Chae Sik Kim ),이재화 ( Jae Hwa Lee ) 한국수학교육학회 2013 수학교육논문집 Vol.27 No.4

본 논문은 한국 근대수학교육의 아버지 이상설(李相卨, 1870-1917)이 자연과학―물리학―에 기여한 내용을 다루고있다. 이상설은 ?수리(數理)?를 쓴 시기를 전후하여, 같은 시기에 붓으로 총 8면에 걸쳐 『백승호초(百勝胡艸)』라는이름의 고전물리학 원고를 써서 남겼다. 분석결과 이 책의 원전은 1879년에 동경제대 의학부 교재로 발간된 『물리학(物理學)』이다. 이상설은 『백승호초』에서 먼저 개념을 정의하고, 일상에서 나타난 대표적 현상을 선록하여 한문으로번역하였고, 『물리학』의 전체 분량에서도 특히 ‘통유성(通有性)’에 중점을 두고 설명하였다. 동양에서 서양의 수리과학이 들어와야만 말할 수 있는 ‘질량보존의 법칙’, ‘타성(惰性, 관성)’과 같은 고전물리학의 중요개념을 포함하는 내용이 19세기 말에 이미 이 책에 소개된 것으로 보아 이상설은 당대의 다른 저술에서 보기 힘들 정도로 당시 일반물리학의 최고수준의 원서를 통해 최신 정보를 수용하고 전파하기 위하여 노력하였음을 볼 수 있다. Sang-Seol Lee(1870-1917) wrote a manuscript BaekSeungHoCho(百勝胡艸) in the late 19th century. BaekSeungHo-Cho was transcribed in classical Chinese from the 1879 Japanese book Physics(物理學) by Teizo Ihimori (1851-1916). Sang-Seol Lee, a famous independence activist, is also called Father of the Modern Mathematics Education of Korea,because of his early contribution to the modern mathematics education in the 19th century. In this paper, we introduce contents of his manuscript BaekSeungHoCho for the first time and discuss the significance of this book. Also, we show his constribution on the introduction to modern physics in the late 19th century Korea.

평행봉 2회전 뒤돌아 무릎 구부려 내리기 동작의 운동학적 분석

이종훈 ( Jong Hun Lee ),이용식 ( Yong Sik Lee ) 한국운동역학회 2004 한국운동역학회지 Vol.14 No.1

J. H. LEE, Y. S. LEE. Kinematic Analysis of Double Backward Somersault on the Parallel Bars. Korean Journal of Sport Biomechanics, Vol. 14, No. 1, pp. 27-40, 2004. The purpose of this study was to provide basic data for improving athletic performances by analyzing the kinematic variables of the Double Backward Somersault on the Parallel Bars through the 3D motion analysis. The subjects in this study were 5 male gymnasts who were ranked as national athletes. The results are as follows. 1. A total time(Mean Time) of performance showed 2.72±0.82 sec. and flight time to landing after releasing was o.87sec.(mean). In order to perform better stable flying movement, the flight time should be increased. 2. In the change of velocity of the center of mass, when the increasing ascension velocity of the upper point was high, the position in the top point was high on releasing. 3. In the position variable of the center of mass, the mean of upper-bottom position in horizontal posture was 242.1±6.5cm, 232.8±6.4cm in releasing, and 265.0±5.6cm in the highest point. This result is explained that the position of center of mass can be raised by using elastic power when wrist raised the bar in the releasing movement. 4. The angle of shoulder joint was 271.1±14.0. Such a big angle influences a negative effect on the releasing velocity, because trunk is not a position in the enough vertical direction. 5. The ankle of hip joint in hand-standing was 191.1±5.9, 118.8±5.3 in releasing, and 122.3±5.3 in taking on. Therefore, the result suggests that trunk should be straightly raised in taking on.

수부 주상골 요부의 전위골절에 대한 수술적 치료

리건영(Kun Yung Lee),이영기(Young Ki Lee),이천동(Cheon Dong Lee),조용만(Yong Man Cho),강흥식(Heung Sik Kang),오상수(Sang Su Oh) 대한골절학회 1997 대한골절학회지 Vol.10 No.1

The authors surveyed the clinical study of 17cases of scaphoid fractures from March 1989 to September 1994 with minimal I year follow up at Department of Orthopedic Surgery, Lee-Rha general Hospital. The following conclusions were obtained through clinical survey. l. Of all l 7 cases, they were l3 males and 4 females; Among the 13 males, 10 cases were aged between 20 and 39 years. forming 56.8% of all. 2. All 17 cases were treated by open reduction. Unions were obtained at average l l.5 weeks in 7 cases treated with Herbert screw fixation and l 2 weeks in l 0 cases treated with K-wire fixation. 3. Two of ten K-wire treated cases resulted in delayed union, one of seven Herbert screw treated cases resulted in delayed union. 4. Unions were obtained at average 20 weeks in 3 cases of delayed union. We concluded that open reduction and K-wire fixation were recomanded for the compatible treatment method of displaced waist fracture of scaphoid.

경골과 골절에 대한 수술적 치료

이건영(Keun Young Lee),박명식(Myung Sik Park),이천동(Cheon Dong Lee),조용만(Yong Man Cho),강흥식(Heung Sik Kang),조규철(Gue Cherl Cho) 대한골절학회 1997 대한골절학회지 Vol.10 No.1

The tibial condylar fracture which involves articular surface of the proximal tibia is common in pedestrian injury of the traffic accident and often produces some disability of the knee joint because of the frequent association with ligamentous and meniscal injuries. Methods of treatment in fracture of the tibial condylas has long been a controversial problems. Recently most authors agree that the method of treatment has to be selected in each individual case and anatomical reduction of fracture and early knee motion are recommended but unsatisfactory results has been reported as between 20% and 40%. The authors analyzed 38 cases of the tibial condylar fractures, which were treated at the orthopedic department of the Lee-Rha general Hospital from 1990 to l994, regarding its type. treatment and results. The results of this study were as follows. l. According to Schatzker classification: the most common fracture was type II. 2. According to Blokker's criteria, 28 cases showed satisfactory results( 74% ). 3. Postoperatively, early knee joint exercise like alternatively applling 90( knee flexion and extension splint were very important factors for good results.

밝은 언어사회

이재식 국제기독교언어문화연구원 1999 기독교언어문화논집 Vol.3 No.-

Dr. Jae Sik Lee. 1999. Brighter Linguistic Society. Collected Papers on Cristian Language Culture. Language is to help make humans human in worldview, culture, and society. Human language is to make society brighter. And brighter language makes it possible for us to establish brighter society. On the basis of brighter language in brighter society, we should establish a new human society of morality which all of us humans aspire for and which can be found in the Bible. Based on these arguments, this paper makes an introductory remark in chapter 1. In chapter 2, this paper argues about worldveiw, culture, and society. In chapter 3, brighter society and human language, and in chapter 4, dark language and brighter language are argued in succession. In chapter 5, this paper proposes that moral society is to be established by brighter language activity, Finally, in chapter 6, this paper also proposes that a new human society of morality which all of us humans in the New Millennium aspire for should be established on the basis of brighter language in brighter society. (Advisor to the Institute, Chairman of the Board of Namseoul University)

Effects of Acrylonitrile and Acrylamide on Nitrile Hydratase Action of Brevibacterium sp . CH1 and CH2

LEE,CHEO YOUNG,JUN SIK HWANG,HO NAM CHANG 한국미생물생명공학회 1991 Journal of microbiology and biotechnology Vol.1 No.3

저압전로의 단락사고에 대한 보호협조 연구

이은우,조규판,김이국,김동희,이광식 영남대학교 공업기술연구소 2000 工業技術硏究所論文集 Vol.28 No.2

This paper describes the protection from line to line fault current caused by the trouble of source the low voltage power line. The decision of interrupting capacity in the low voltage circuit breaker is based on foreign rules, environment and actual condition within a country. Congregation of full capacity rating, selective breaking method and cascade breaking method is based on relevance reference and catalog of a manufacturing company. From above result, we obtain the method of optimum coordination and contrive the convenience of actual experience application according to the importance of electricity installation. The calculation of breaking capacity and the application of breaking method investigate actual condition in the case of design of electricity installation established and enlarged for personal use in Gumi, Chilgok area recently and present the point at issue and countermeasure. In the future, I think that this data contribute not only the preventing of electricity installation accident but also of electricity installation accident.