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The Regulation and Function of Histone Methylation
YanXiao Niu;Jiaoteng Bai,Shuzhi Zheng 한국식물학회 2018 Journal of Plant Biology Vol.61 No.6
Histones are wrapped around by genomic DNAto form nucleosomes which are the basic units of chromatin. In eukaryotes histones undergo various covalent modificationssuch as methylation, phosphorylation, acetylation, ubiquitinationand ribosylation. Histone modifications play a fundamentalrole in the epigenetic regulation of gene expression inmulticellular eukaryotes. Histone methylation is one of themost important modifications occurring on Lysine (K) andArginine (R) residues of histones, dynamically regulated byhistone methyltransferases and demethylases. Identificationsof such histone modification enzymes and to study how theywork are the most fundamental questions needs to beanswered. Uncovering the regulation and functions of thevarious histone methylation enzymes will help us to betterunderstand the epigenetic code. This review summarizes theregulation of histone methyltransferases activity, the recruitmentof methyltransferases and the distribution patterns andfunction of histone methylations.
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Unipolar photonic memristive-like nonlinear switching in split-ring resonator based metamaterials
Hongya Wu,Liang Xu,Shikao Shi,Guanglei Zhang,Guoqiang Qin,Caihui Wang,Gang Yu,Ji Zhou,Shuzhi Zheng 한국물리학회 2018 Current Applied Physics Vol.18 No.4
Photonic memristor, which performs the function as memristor working on electromagnetic fields, can accelerate the development of all-optical network. A unipolar photonic memristive-like switching behavior in split-ring resonator based metamaterials was reported. Transmission-power (T-P) loops are observed in the metamaterials. And the T-P loops change with the detect frequency which indicates the tunability and designability of the photonic memristor. These behaviors are attributed to the increasing dielectric constant of MgTiO3 ceramic caused by the interaction of sample and electromagnet field. The mechanism supplies a general foundation for photonic memristors which can be used from radio frequency to optical wavelength.
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