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      • 詩經正變設考

        金時俊 서울대학교 동아문화연구소 1979 東亞文化 Vol.16 No.-

        It was written at the Mao Shi prefaces (毛詩序) that Shi Jing was divided into two groups; the Zheng Poem and the Bian Poem. According to this, many scholars published various assertions on how to distinguish the Zheng Poem from the Bian Poem in Shi Jing. Conseguently, these assertions were classified into four sorts. 1) Classification by the chronological order according to the political rise and fall 2) Distinction between eulogy and satire 3) Distinction the Poem which was accompanied by music from the poem which was not accompanied by it, 4) Classification by the style of the poem My study on each assertion leads to the following conclusion: 1) Although those scholars who made the first assertion defined that Shi Jing was published by the chronological order and they distinguished the Zheng Poem from the Bian poem by the table of contents, it is proved that Shi Jing was not published by the chronological order. 2) Those scholars who made the second assertion concluded that Shi-Jing was distinguished between eulogy and satiry at every prologue in Mao Shi and that the Zheng poem and the Bian Poem could be divided into eulogy or satire accordingly. But it is proved herein that the distinction eulogy from satire in Mao Shi prefaces was possible by the country and chronology without the definite standard even though the contents of the poem were the same. 3) Those scholars who made the third assertion divided Shi Jing into two parts. One that was accompanied by music was called the Zheng Poem and the other that was accompanied by music was called the Bian Poem. But it is proved that all of Shi Jing were accompanied by music 4) Those who made the fourth assertion distinguished between the Zheng Poem and the Bian Poem by the style of the Poem. But looking into the style, it is proved that the distinction between the Zheng Poem and the Bian Poem is the style itself. Thus, the above classifications seem to be unreasonable so far. Then, why did these assertions come to rise? These assertions were due to the Han scholars who regarded the poem as a remonstration. They attempted to classify the Zheng Poem as the poem of admonition and the Bian poem as that of warning. But they did not succeed in it.

      • Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

        Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

        Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

      • KCI등재후보
      • KCI등재

        Hot Deformation Characteristics and Processing Map Analysis of Pre-Forged AZ80 Magnesium Alloy

        Shi‑quan Huang,Ming Lu,Sheng‑lan Luo,Hai‑lin He,You‑ping Yi 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

        The hot deformation behavior of pre-forged AZ80 magnesium alloy is investigated by the isothermal compression tests attemperatures of 523–683 K and strain rates of 0.0001–0.1 s−1, and analyzed by the processing maps for guiding isothermaldie forging. Flow localization and even cracking occurs at low temperatures and high strain rates, where shear deformationdegree shows a positive correlation with the ��( ̇�� ) value. Two stability regions with high efficiency is found out by theprocessing maps. At common stability region with high temperatures and low strain rates, peak power dissipation efficiencydoes not represent optimum deformation condition as reported in other materials. A Z parameter criterion is introduced forparameters optimization. javascript:void(0); a new stability domain of 523–590 K and 0.0001–0.01 s−1 is observed, which istypical for fine microstructure composed of equiaxed clean α-Mg grains and big particles both about 1 μm (573 K/0.01 s−1).Super plasticity is speculated to occur at that condition.

      • SCOPUSKCI등재
      • 우리나라 公的扶助政策에 관한 硏究 : 生活保護事業을 中心으로 Focused on the Life Care Program

        盧時平 서경대학교 1989 論文集 Vol.17 No.-

        Korea was rapidly enlarging her economic scale by successful implementation of five consecutive terms of five year economic development plans. But the economic growth of Korea so stressed on the outward. phisical growth that it raised the various problem such as the unbalances between regions, classes and industries. The most important problem to solve in Korea is that of the conflicts between classes. Public assistance is very important program to solve this problem in Korea. The purpose of this study is, therefore, to find out the desirable direction of public assistence in Korea. This thesis is composed of 6 Chapters. These are 1) Introduction 2) The System of Public assistance 3) Theoretical Background 4) Current Situation Analysis 5) Evaluation 6) Conclusion. In Chapter Ⅱ. The system of public assistance is devided into 2 parts. These are ⅰ) The concept of public assistance ⅱ) The system of public assistance in Korea. In Chapter Ⅲ. Theoretical background introduces the framework and method for analysis of Korea public assitance program. In Chapter Ⅳ, Ⅴ. I tried to analyse and evaluate the life care program in Korea according to dimensions of allocation, provision, delivery system and finance. In Chapter Ⅵ, I suggested some policy recommendations for Korean public assistance program. These are : 1) It is urgent to secure the professional for selection of the recipients. 2) In the dimension of allocation, the decision time for eligibility of the recipients should be flexible based on necessity principle. 3) In the dimension of provision, the lavel of minimum living standard should be measured by scientific methods. 4) In the dimension of delivery system, it is necessary to reorder of welfare administration organization for recipients' accessibility. 5) In the dimension of finance, various devices should be considered for securing finance.

      • 효소 중합반응에 의한 인공 cDNA 클론의 형성

        유시현,권무식 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.2

        The sequence-specific DNA binding protein, PU.1 common to macrophage and B cell in mammals, is one of the transcription activators. Its DNA binding activity seems to correlate with the phosphorylation of specific serine residue(s). It is, however, not clear that which serine(s) could be phosphorylated for the activation of PU.1. To understand the phosphorylation mechanism of the transcription factor, the first nucleotide coding the 11th amino acid [TCC] of PU.1, "Thymidine", was substituted with "Guanidine" by site-directded mutagenesis. The mutant PU.1 cDNA restricted by Xba I and Hind III, was ligated into Xbal-HindIII cut pBluescript KS+, and then transformed into E.coli JM109 to generate a new mutant clone of PU.1. The mutant will be instrumental in evaluating a plausible phosphorylation site of PU.1.

      • 現代官僚制祖織의 諸問題

        梁始浩,李炫宰 건국대학교 행정대학원 1982 建國大學校 行政大學院 硏究論叢 Vol.10 No.-

        The limits and problems of modern bureaucratic organization have been inquired into. Accordingly, it follows that a number of problems are presented together with the internal contradictions of bureaucracy itself and the changes of environmental factors. However, the modern bureaucratic organization and, in particular, the critical contents about bureaucracy by Max Weber are not appropriate to all organizations. Particularly, public administration produces invisible property impossible to be measured. The Max Weberian bureaucrary, therefore has to be recognized for its validity from the aspect of the security of responsibilities. It is, therefore, emphasized that the modern society be given an organization made public and a professional sense of value as well as its mobility of organization. In the light of these facts, the modern bureaucratic organization should be resolutely reformed within the scope of not failing to notice the characteristics of classical bureaucratic organization lack of reality.

      • 화재조사에 관한 수사제도의 실태 및 개선방안

        차시환 김천대학교 2010 김천대학교 논문집 Vol.30 No.-

        In this study, especially during the fire accident, with distinguishing arson from accidental fire, arson is one of the violent criminal so this study try to research that ; in spite of the arson, fire officers and police officers at the scene can not clarify substantial cause of the accident unless there is real evidence or witness, because they treated the case as unknown or accidental fire. Cases that are really hard to reveal signs of murder, cause of suspect who com-mit arson after the murder to conceal it have increased. And cases of suffering unfairness due to insurance fraud that is designed on insurance payment using vulnerability of fire insurance are more and more increasing. There is no exact data about the lack of expertise in fire investigations and the case of stolen insurance money from good insurance members. So this study try to analyze that compart to foreign examples, our country's arson and accidental fire type and cases. And thus this study try to support theoretically (admissibility of evidence) that after the fire accident, survey results from the first incident until the investigation is responsible for the substantive out the truth.

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