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Chun, Se-Woong,Lee, Hack-Jin,Nam, Koong-Ho,Sohn, Chul-Ho,Kim, Kwang Dong,Jeong, Eun-Jin,Chung, Sun G.,Kim, Keewon,Kim, Dong-Joo Wiley (John WileySons) 2017 Journal of orthopaedic research Vol.35 No.1
<P>Spinal stenosis is a common degenerative condition. However, how neurogenic claudication develops has not been clearly elucidated. Moreover, cerebrospinal fluid physiology at the lumbosacral level has not received adequate attention. This study was conducted to compare cerebrospinal fluid hydrodynamics at the lumbosacral spinal level between patients with spinal stenosis and healthy controls. Twelve subjects (four patients and eight healthy controls; 25-77 years old; seven males) underwent phase-contrast magnetic resonance imaging to quantify cerebrospinal fluid dynamics. The cerebrospinal fluid flow velocities were measured at the L2 and S1 levels. All subjects were evaluated at rest and after walking (to provoke neurogenic claudication in the patients). The caudal peak flow velocity in the sacral spine (-0.25 +/- 0.28 cm/s) was attenuated compared to that in the lumbar spine (-0.93 (+/-) 0.46 cm/s) in both patients and controls. The lumbar caudal peak flow velocity was slower in patients (-0.65 +/- 0.22 cm/s) than controls (-1.07 +/- 0.49 cm/s) and this difference became more pronounced after walking (-0.66 +/- 0.37 cm/s in patients, -1.35 +/- 0.52 cm/s in controls; p = 0.028). The sacral cerebrospinal fluid flow after walking was barely detectable in patients (caudal peak flow velocity: -0.09 +/- 0.03 cm/s). Cerebrospinal fluid dynamics in the lumbosacral spine were more attenuated in patients with spinal stenosis than healthy controls. After walking, the patients experiencing claudication did not exhibit an increase in the cerebrospinal fluid flow rate as the controls did. Altered cerebrospinal fluid dynamics may partially explain the pathophysiology of spinal stenosis. (C) 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.</P>
Extraforaminal Extrusion of Intervertebral Disc Misdiagnosed as Neurogenic Tumor: a Case Report
Chun, Se-Woong,Park, Young-Seop,Heo, Won,Baek, Kyeonghee,Moon, Jin Il Korean Society of Magnetic Resonance in Medicine 2017 Investigative Magnetic Resonance Imaging Vol.21 No.2
A 55-year-old male presented with dysesthesia of the right anteromedial thigh. A magnetic resonance image revealed a globular mass at the right extraforaminal area of the L3/4 level. Based on the diagnosis of neurogenic tumor, surgical excision was performed. The surgical impression and pathology confirmed extrusion of intervertebral disc. In a retrospective review of the magnetic resonance image, we noticed a fibrillary pattern directed from the intervertebral disc space to the lesion, and disrupted annulus fibrosus and indentation caused by the ring apophysis. We suggest aforementioned features, indicative of intervertebral disc lesions, to be checked when interpreting mass lesions around the intervertebral foramen.
Inter-rater Agreement for the Clinical Dysphagia Scale
Se Woong Chun,Byung-Mo Oh,,Seung Ah Lee,정일영,Jaewon Beom,Tai Ryoon Han 대한재활의학회 2011 Annals of Rehabilitation Medicine Vol.35 No.4
Objective To investigate the inter-rater agreement for the clinical dysphagia scale (CDS). Method Sixty-seven subjects scheduled to participate in a video-fl uoroscopic swallowing study (VFSS) were preexamined by two raters independently within a 24-hour interval. Each item and the total score were compared between the raters. In addition, we investigated whether subtraction of items showing low agreement or modifi cation of rating methods could enhance inter-rater agreement without signifi cant compromise of validity. Results Inter-rater agreement was excellent for the total score (intraclass correlation coefficient (ICC): 0.886). Four items (lip sealing, chewing and mastication, laryngeal elevation, and reflex coughing) did not show excellent agreement (ICC: 0.696, 0.377, 0.446, and κ: 0.723, respectively). However, subtraction of each item either compromised validity, or did not improve agreement. When redefi ning ‘history of aspiration’ and ‘lesion location’ items, the inter-rater agreement (ICC: 0.912, 0.888, respectively) and correlation with new videofluoroscopic dysphagia score (PCC: 0.576, 0.577, respectively) were enhanced. The CDS showed better agreement and validity in stroke patients compared to non-stroke patients (ICC: 0.917 vs 0.835, PCC: 0.663 vs 0.414). Conclusion The clinical dysphagia scale is a reliable bedside swallowing test. We can improve inter-rater agreement and validity by refining the ‘history of aspiration’ and ‘lesion location’ item.
Sakong, Chun,Kim, Se Hun,Yuk, Sim Bum,Namgoong, Jin Woong,Park, Se Woong,Ko, Min Jae,Kim, Dong Hoe,Hong, Kug Sun,Kim, Jae Pil Wiley (John WileySons) 2012 Chemistry - An Asian Journal Vol.7 No.8
<P>Three new triphenylamine dyes that contain alkylthio-substituted thiophenes with a low bandgap as a π-conjugated bridge unit were designed and synthesized for organic dye-sensitized solar cells (DSSCs). The effects of the structural differences in terms of the position, number, and shape of the alkylthio substituents in the thiophene bridge on the photophysical properties of the dye and the photovoltaic performance of the DSSC were investigated. The introduction of an alkylthio substituent at the 3-position of thiophene led to a decrease in the degree of redshift and the value of the molar extinction coefficient of the charge-transfer band, and the substituent with a bridged structure led to a larger redshift than that of the open-chain structure. The introduction of bulky and hydrophobic side chains decreased the short-circuit photocurrent (J(sc)), which was caused by the reduced amount of dye adsorbed on TiO(2). This resulted in a decrease in the overall conversion efficiency (η), even though it could improve the open-circuit voltage (V(oc)) due to the retardation of charge recombination. Furthermore, the change in solvents for TiO(2) sensitization had a critical effect on the performance of the resulting DSSCs due to the different amounts of dye adsorbed. Based on the optimized dye bath and molecular structure, the ethylene dithio-substituted dye (ATT3) showed a prominent solar-to-electricity conversion efficiency of 5.20%.</P>