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        COVID-19: An Early Review of Its Global Impact and Considerations for Parkinson’s Disease Patient Care

        Roongroj Bhidayasiri,Sasivimol Virameteekul,Jong-Min Kim,Pramod Kr. Pal,Sun Ju Chung 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.2

        While many infectious disorders are unknown to most neurologists, coronavirus disease 2019 (COVID-19) is very different. Ithas impacted neurologists and other health care workers, not only in our professional lives but also through the fear and panicwithin our own families, colleagues, patients and their families, and even in the wider public. COVID-19 affects all sorts of individuals,but the elderly with underlying chronic conditions are particularly at risk of severe disease, or even death. Parkinson’s disease(PD) shares a common profile as an age-dependent degenerative disorder, frequently associated with comorbidities, particularlycardiovascular diseases, so PD patients will almost certainly fall into the high-risk group. Therefore, the aim of this review isto explore the risk of COVID-19 in PD based on the susceptibility to severe disease, its impact on PD disease severity, potentiallong-term sequelae, and difficulties of PD management during this outbreak, where neurologists face various challenges on howwe can maintain effective care for PD patients without exposing them, or ourselves, to the risk of infection. It is less than sixmonths since the identification of the original COVID-19 case on New Year’s Eve 2019, so it is still too early to fully understandthe natural history of COVID-19 and the evidence on COVID-19-related PD is scant. Though the possibilities presented arespeculative, they are theory-based, and supported by prior evidence from other neurotrophic viruses closely related to severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2). Neurologists should be on high alert and vigilant for potential acuteand chronic complications when encountering PD patients who are suspected of having COVID-19.

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