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      • KCI등재

        大邱市 所在 老人福祉會館 利用者의 虐待經驗 實態

        장세희,권진희,황병덕,이성국 대한보건협회 2003 대한보건연구 Vol.29 No.1

        The purpose of this study is to examine current status of elderly abuse by their own children. The study was performed with sample group of 385 people over 60 years old(Male: 135, Female: 2-50) Daegu city residents, who attended the senior welfare center. By categorizing specific type of abuse experience, the study showed B.l%(male: 25.2%, female: 22.0%) of verbal * psychological abuse, 4.9%(male: 3.7%, female: 5.6%) of permissive abuse, and 4.7%(male: 5.2%, female: 4.4%) of financial abuse. There was no record of physical abuse experience. In the review of elderly abuse experience following general characteristics, especially in case of female elderly, the difference in verbal psychological abuse experience was observed depending on the existence of spouse and composition of family. And there was also a difference in financial abuse experience related to health condition. In the study of elderly abuse experience according to the financial status, the female elderly who were a pool economic status had experienced comparatively high level of verbal . psychological abuse. In the review of reaction against abuse, direct confrontation(35.0%) was the most dominant among male elderly, however, majority of female elderly(56.5%) was found to be bear with the suffer . The main reason for such endurance was for the sake of own children . There was only one elderly(0.9%) who had ever reported to the police with abuse experience.

      • 수용성 절삭유제 내에서 Saccharomyces cerevisiae와 Escherichia coli의 성장에 관한 연구

        정광진,최희영,김장규,원성호,김남기 成均館大學校 科學技術硏究所 1992 論文集 Vol.43 No.2

        The water-soluble cutting oil was used in the type of the mixture of additive lubricant, surfactant, etc., as the organic nutrients, with water. Therefore it was easy to be affected by microbials ; they brought the bad odor by putridity, decreased the cutting property, and destroyed the emulsion phase. In the study using cells, Saccharomyces cerevisiae and Escherichia coli, we studied the effect of concentration and dilution ratio on the growth of cells and the cell growth rate, the pH variance and the change of oil's concentration. The results obtained in this experiment were as follows : 1) The result of test dilution ratio (water:oil) vs. cell growth was that by using E. coli, the growth was better in this order in emulsion type (sample 1) 50:1 > 30:1 > 100:1, and in the soluble type (sample 2) the order was 100:1 > 50:1 > 30:1. The effect of the cutting oil's concentration on the Saccaromyces cerevisiae's was less in this order 100:1 < 50:1 < 30:1 ; the maximum growth was occurred at 100:1. 2) In sample 1 by using E, coli, pH range was changed from 9.5 to 8.0 and refractive index(the cutting oil's concentration) was changed from 1.3327 to 1.3318. And in the test using S. cerevisiae, pH range was varied from 9.5 to 6.2 and refractive index was changed from 1.3330 to 1.3310. In sample 2 by using E. coil, pH was changed to 8.9 and refractive index was changed from 1. 3315 to 1.3313 and in that of using S cerevisiae, pH was changed to 8.1 and refractive index was decreased from 1.3355 to 1.3340.

      • KCI등재

        강원지방 소나무와 잣나무의 산불 연료특성 비교

        Sung Yong Kim,Young Jin Lee,Mi Na Jang,Chun Geun Kwon,Byung Doo Lee,He Young Ahn 위기관리 이론과 실천 2017 Crisisonomy Vol.13 No.4

        본 연구에서는 강원지방에 분포하는 소나무와 잣나무를 대상으로 지표층 및 수관층 연료의 특성을 파악하고 수관화 전이 및 확산 위험성을 비교·분석 하였다. 지표층 연료를 수종별로 채취하였으며, 수종별 16개의 표본목을 벌채하여 수관층 연료특성을 분석하였다. 본 연구결과에 의하면, 지표층 수분함량은 잣나무가 높았으나, 수관층 수분함량은 두 수종 간 유사하게 나타났다. 수관층 잎의 비율은 잣나무(34.4%)가 소나무(25.7%)에 비해 많이 분포하였고, 연소 가능한 연료는 소나무 55.8%, 잣나무 55.6%의 비율로 유사하였다. 수관층 연료 추정식의 조정결정계수(R 2 adj )는 모든 수관 부위에서 0.850 이상으로 나타났다. 임분 단위 수관연료특성에서는 잣나무의 수관체적 공간이 소나무보다 적었지만, 그 안에 포함된 연료량이 많아 총 수관연료밀도는 약 1.56배, 연소가능한 수관연료밀도는약 1.68배 높은 결과가 나타났다. This study identified fuel characteristics of surface and crown and analyzed crown fires on Pinus densiflora and Pinus koraiensis stands in Gangwon Province in Korea. Fifteen surface fuels of each tree type were sampled and 16 trees of each species were destructively sampled to identify crown fuel characteristics. Pinus koraiensis has higher surface fuel moisture content due to the difference in crown cover, although the two types show similar crown fuel moisture content. Pinus koraiensis (34.4%) has more crown needles than Pinus densiflora (25.7%), but two species have similar combustible of available fuel, 55.8% and 55.6%, respectively. The adjusted coefficients of determination(R 2 adj ) values were high (more than 0.850) in all crown fuel classes. The canopy bulk density of Pinus koraiensis was 1.56 times higher than that of Pinus densiflora, whereas the available canopy bulk density of Pinus koraiensis was 1.68 times higher despite the smaller canopy volume.

      • SCISCIESCOPUS

        Enhanced apoptotic effect of combined modality of 9-hydroxypheophorbide alpha-mediated photodynamic therapy and carboplatin on AMC-HN-3 human head and neck cancer cells.

        He, Peijie,Ahn, Jin-Chul,Shin, Jang-In,Hwang, Hee-Jun,Kang, Jung-Wook,Lee, Sang-Joon,Chung, Phil-Sang National Hellenic Research Foundation 2009 ONCOLOGY REPORTS Vol.21 No.2

        <P>Photodynamic therapy (PDT) has been developed as an effective treatment for malignant disease. Carboplatin (CBDCA), a less nephrotoxic analog of cisdiamminedichloroplatinum (cisplatin), has been widely used for the treatment of multiple malignancies. In this study, we investigated the cytotoxic and apoptotic effect of combined modality of 9-hydroxypheophorbide alpha (9-HPbD)-mediated PDT and CBDCA on AMC-HN-3 human head and neck cancer cell line in vitro. The attached AMC-HN-3 cells were incubated with CBDCA (0.04 mg/ml) for 24 h at 37 degrees C and followed by photosensitization with 9-HPbD for 6 h and laser irradiation with 670 nm diode laser at an intensity of 2.0 J/cm(2) for activating 9-HPbD for 15 min. Then MTT reduction assay and Hoechst 33342 and propidium iodide (PI) double staining were used respectively to measure the cytotoxicity and nuclear morphology at 24 h after PDT. Expression of caspase-3, -9 and poly(ADP-ribose) polymerase (PARP) was detected at 0, 3, 6 and 12 h after irradiation through Western blotting techniques. Compared with PDT and CBDCA alone groups, there was more cytotoxicity and enhanced apoptotic cell death in combination groups. The peaked expression of cleaved form of caspase-3, -9 and PARP occurred approximately 3 h after PDT. There was stronger expression of cleaved caspase-3, -9 and PARP in combination groups than that in PDT or CBDCA alone groups. This study demonstrates that the combined modality resulted in enhanced apoptotic cell death as well as cytotoxic effect on AMC-HN-3 cells in vitro, which suggests the feasibility of combined modality and the possibility of reducing the effective dosage of 9-HPbD and CBDCA and lowering the side effects on normal cells.</P>

      • KCI등재

        High Glucose Causes Human Cardiac Progenitor Cell Dysfunction by Promoting Mitochondrial Fission: Role of a GLUT1 Blocker

        ( He Yun Choi ),( Ji Hye Park ),( Woong Bi Jang ),( Seung Taek Ji ),( Seok Yun Jung ),( Da Yeon Kim ),( Songhwa Kang ),( Yeon Ju Kim ),( Jisoo Yun ),( Jae Ho Kim ),( Sang Hong Baek ),( Sang Mo Kwon ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.4

        Cardiovascular disease is the most common cause of death in diabetic patients. Hyperglycemia is the primary characteristic of diabetes and is associated with many complications. The role of hyperglycemia in the dysfunction of human cardiac progenitor cells that can regenerate damaged cardiac tissue has been investigated, but the exact mechanism underlying this association is not clear. Thus, we examined whether hyperglycemia could regulate mitochondrial dynamics and lead to cardiac progenitor cell dysfunction, and whether blocking glucose uptake could rescue this dysfunction. High glucose in cardiac progenitor cells results in reduced cell viability and decreased expression of cell cycle-related molecules, including CDK2 and cyclin E. A tube formation assay revealed that hyperglycemia led to a significant decrease in the tube-forming ability of cardiac progenitor cells. Fluorescent labeling of cardiac progenitor cell mitochondria revealed that hyperglycemia alters mitochondrial dynamics and increases expression of fission-related proteins, including Fis1 and Drp1. Moreover, we showed that specific blockage of GLUT1 improved cell viability, tube formation, and regulation of mitochondrial dynamics in cardiac progenitor cells. To our knowledge, this study is the first to demonstrate that high glucose leads to cardiac progenitor cell dysfunction through an increase in mitochondrial fission, and that a GLUT1 blocker can rescue cardiac progenitor cell dysfunction and downregulation of mitochondrial fission. Combined therapy with cardiac progenitor cells and a GLUT1 blocker may provide a novel strategy for cardiac progenitor cell therapy in cardiovascular disease patients with diabetes.

      • KCI등재

        Allometric Equations for Crown Fuel Load of Pinus rigida Stands in South Korea

        Sung Yong Kim,Chun Geun Kwon,He Young Ahn,Byung Doo Lee,Mi Na Jang 위기관리 이론과 실천 2017 Crisisonomy Vol.13 No.12

        본 연구의 목적은 리기다소나무림의 수관층 연료량 추정식을 개발하는 것이다. 이를 위해 충남 예산군 소재에 분포하고 있는 리기다소나무를 흉고직경별로 20본 벌채하였으며, 수관층에서 잎과 가지를 분류하고, 가지의 고사여부와 더불어 굵기별로 구분하여 무게를 측정하였다. 연료량 추정식은 흉고직경 또는 흉고직경과 수고를 독립변수로 이용하여 개발하였다. 각 부위별 수관층 연료량을 보면 가장 높은 비율을 차지하는 부위는 >4cm 가지 (9.521kg, 26.08%)로 나타났으며, 잎 (8.852kg, 24.25%), 2-4cm 가지 (7.226kg, 19.79%), 1-2cm 가지 (3.920kg, 10.74%), <0.5cm 가지 (2.890kg, 7.92%), 0.5-1cm 가지 (2.711kg, 7.42%), 죽은가지 (1.387kg, 3.80%) 순으로 나타났다. 평균적으로 lnWt=β0+β1 lnD 식에서 조정결정계수 (R2adj = 0.9870-0.8596)는 높고, 표준추정오차 (S.E.E. = 0.1670-0.6859)는 낮았으나, 추정식 간의 차이는 적었다. The objective of this study was to develop an allometric equation to estimate crown fuel load of Pinus rigira in South Korea. Twenty representative trees were cut down for samples, and crown fuel were classified according toits component(needle or branch), life (alive or dead), and diameter(<0.5cm, 0.5-1cm, 1-2cm, 2-4cm, >4cm). A fuel load allometric equation was developed with diameter at breast height(DBH) and tree height as independent variables. The result of this study showed that the > 4cm branches recorded the largest fuel load (9.521kg), followed by needles fuel (8.852kg), live branches with size ranging from 2 to 4cm (7.226kg), 1-2cm (3.920kg), <0.5cm (2.890kg), 0.5-1cm (2.711kg) and dead branches (1.387kg) as the lowest. On average, the adjusted coefficient of determination was high (R2adj = 0.9870-0.8596) and standard error of estimate was high (S.E.E. = 0.1670-0.6859) in allometric equation,lnWt=β0+β1 lnD. However, the differences in R2adj and S.E.E. between the equations were not significant.

      • KCI등재

        CoP(Community of Practice) 활동에 영향을 미치는 조직환경과 동기요인에 관한 연구: CoP 발전단계에 따른 탐색적 연구

        장희영 ( He Young Jang ),고일상 ( Il Sang Ko ) (주)엘지씨엔에스(구 LGCNS 엔트루정보기술연구소) 2012 Entrue Journal of Information Technology Vol.11 No.3

        CoP는 장기적으로 기업의 경쟁력을 확보하기 위한 원천이며 단기적으로는 기업이 직면한 문제들을 해결하기 위한 전문성을 지닌 집단으로서 가치를 지닌다. 이러한 CoP를 육성하기 위해서 다양한 전략이 수행되고 있으나 그 효과는 노력에 비해 큰 성과를 보이지 못하고 있다. 이 연구에서는 CoP 발전단계를 이해하여 차별화된 발전전략을 수립해야 함을 인식하고, CoP 활동에 영향을 미치는 요인들이 발전단계에 따라 차이를 있음을 검증하였다. 이를 위해 CoP 발전단계에 대한 선행연구결과를 바탕으로 CoP 발전단계를 개발하고, 이 단계에 속하는 집단을 대상으로 실증 연구를 수행하였다. 연구결과 CoP를 통한 지식공유에 영향을 미치는 요인 중 적합한 정보시스템, 리더의 참여, 지각된 위험 그리고 조직환경이 통계적으로 유의한 결과를 보였다. 더불어, 네트워크 활동에 영향을 미치는 요인 중에서는 리더의 참여, 지각된 위험 그리고 조직환경이 CoP 발전단계에 따라 통계적으로 유의한 결과를 가진 것으로 나타났다. CoP is one of the sources for securing the competitiveness of a company in the long-term, while in the short-term it is va-lued as a group that possesses the expertise to solve the problems that the company is directly faced with. Various strategies are carried out to develop CoP, but its effect has failed to show results. This research emphasizes the need to establish a diffe-rentiated development strategy by understanding the levels of maturity of the CoP. And verified the differences according to the maturity model related to the elements influencing CoP activities. For this, based on the results of the prior research, reor-ganizing the maturity levels to enable substantiation, and verified differences by targeting groups belonging to each level. From among the factors affecting knowledge sharing through CoP, this study revealed significantly differences in the areas of appropriate IT, participation of a leader, perceived danger and organizational environment. Also, from the factors affecting networking activities, involvement of a leader, perceived danger and organizational environment were revealed to have signif-icantly differences according to the levels of the maturity model of CoP.

      • KCI등재

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