Adaptation of block chain technology in SCM for steering managerial strategies: investigative study under Indian context

Atul Kumar Sahu,Abhijeet Katyayan,Umesh Khandey,Prashant Jangde,Anoop Kumar Sahu,Nitin Kumar Sahu 인하대학교 정석물류통상연구원 2023 JOURNAL OF INTERNATIONAL LOGISTICS AND TRADE Vol.21 No.1

Purpose – Block chain technology (BCT) has apparent capability of handling information in digital format, which has dragged attention of the practitioners for its utility in industrial and manufacturing practices. Conversely, the managerial adoption of BCT is relatively limited, which motivated the authors to identify crucial dimensions that can persuade the acceptance of BCT from an executive perspective. Thus, the present study is aimed to conduct to understand crucial barriers under BCT for managerial implementation in supply chain management (SCM) of small and medium enterprises (SMEs). Design/methodology/approach – The present study investigated evident barriers to understand implementation of BCT. A questionnaire based survey is performed to collect primary data from service and manufacturing based companies in India. Survey responses are received online and the data is analyzed in a scorecard. The scorecard embedded the scribed entries of Likert scale to determine the relative score. Findings – In present study, sixteen barriers from three categories named as technological, organizational and environmental are evaluated, where, five sub-barriers from technological domain, seven sub-barriers from organizational domain and four sub-barriers from environmental domain are evaluated. The findings of the study determined that the three factors, i.e. “complexity in setup/use”, “Security and privacy concern” and “Technological awareness” mostly affect the adaptation of BCT in SCM. Conversely, “Market dynamics”, “Scalability” and “Cost” do not influence the intention to adopt the technology. Originality/value – Only few studies have endeavored to ascertain the BCT adoption in SCM of SMEs in developing country like India. Thus, the study is filling a momentous gap of mapping BCT dimensions in the scholastic literature. The findings are expected to enable SMEs to understand important factors to be considered for adopting BCT in their curriculum. Furthermore, the study may benefit the BCT developers and suppliers to endure customized solutions based on the findings.

Synthesis and Evaluation of Antimicrobial Activity of 1, 3, 4-Thiadiazole Analogues for Potential Scaffold

Sahu, Sagar,Sahu, Tanesh,Kalyani, Gunjan,Gidwani, Bina KOREAN PHARMACOPUNCTURE INSTITUTE 2021 Journal of pharmacopuncture Vol.24 No.1

Objectives: Pathogenic microbes are causal agents for various types of severe and even lethal infectious diseases. Despite of development in medication, bacterial and fungal infections still persist to be a vital problem in health care. Bacteria and several fungal species have shown resistance to antibiotics used in treatment to current medications. Therefore, it is a considerable field of interest in the design and development of novel compounds with antimicrobial activity. Methods: The compounds bearing a heterocyclic ring play an imperative role among other organic compounds with pharmacological activity used as drugs in human for control and cure of various infections. Thiadiazoles containing nitrogen-sulfur atom as part of their cyclic structure which shown wide-ranging application as structural units of biologically active molecules and are very useful intermediates in Medicinal Chemistry. Results: The effectiveness of the thiadiazole nucleus was established by the drugs currently used for the treatment of various infections. 1,3,4-Thiadiazoles and some of their derivatives are widely studied because of their broad spectrum of pharmacological activities. Conclusion: In the present work, a series of 1,3,4-Thiadiazole derivatives were synthesized by cyclization of a group of various benzaldehyde with thiosemicarbazide in the presence of various reagent like FeCl3, HCHO by losing a molecule of water. These derivatives were found to possess prominent antimicrobial activity.

Winter Thermal Inversion and Trichodesmium Dominance in North-Western Bay of Bengal

Biraja Kumar Sahu,Sanjiba Kumar Baliarsingh,Aneesh A. Lotliker,Chandanlal Parida,Suchismita Srichandan,Kali Charan Sahu 한국해양과학기술원 2017 Ocean science journal Vol.52 No.2

Clear thermal inversion was observed with cold surface waters (< 24°C) overlying the warm (> 26°C) subsurface water in the coastal waters of the northwestern Bay of Bengal during winter (January 2015). Simultaneously, preponderance of the cyanobacteria Trichodesmium erythraeum was observed dominating the phytoplankton community with > 90% of total population, reaching maximum density of 9.8 × 105 filaments/L. Further, the Trichodesmium predominance was associated with low water temperature (< 24°C).

Extraction of copper by leaching of electrostatic precipitator dust and two step removal of arsenic from the leach liquor

N. K. Sahu,Barsha Dash,Suchismita Sahu,I. N. Bhattacharya,T. Subbaiah 한국화학공학회 2012 Korean Journal of Chemical Engineering Vol.29 No.11

The paper deals with the extraction of copper from the deposited material of the liner of the electrostatic precipitator (ESP) of the copper smelter plant. These precipitates of ESP liner (ESP dust) generally contain mixed phases of copper and arsenic. An attempt is made to extract copper from ESP dust, subsequently removing arsenic from the leach liquor. The ESP dust containing paramelaconite (6CuO·Cu2O), α-domeykite (Cu3As), metadomeykite (Cu3As),enargite (Cu3AsS4) and (Cu,Fe) SO4·H2O is not a naturally occurring geological mineral; thus comparatively high acid concentration and temperature are required to break the matrix of this mixed material so as to liberate the content. The leaching efficiency of copper was 97% at 97 oC. The acid concentration of 1.5M and pulp density of 20% was found to be optimum. The removal of arsenic as ferric arsenate was carried out in two stages: increasing the pH and precipitation of arsenic by adjusting pH of the solution and by adding ferrous sulfate and hydrogen peroxide. The optimum removal of arsenic was 95% when pH was raised to 2.35 followed by precipitation. The key progression of the process is the recovery of copper from ESP dust as well as removal of arsenic from the leach liquor.

Synonymous Codon Usage Analysis of the Mycobacteriophage Bxz1 and Its Plating Bacteria M. smegmatis: Identification of Highly and Lowly Expressed Genes of Bxz1 and the Possible Function of Its tRNA Species

Sahu, Keya,Gupta, Sanjib Kumar,Ghosh, Tapash Chandra,Sau, Subrata Korean Society for Biochemistry and Molecular Biol 2004 Journal of biochemistry and molecular biology Vol.37 No.4

The extent of codon usage in the protein coding genes of the mycobacteriophage, Bxz1, and its plating bacteria, M. smegmatis, were determined, and it was observed that the codons ending with either G and / or C were predominant in both the organisms. Multivariate statistical analysis showed that in both organisms, the genes were separated along the first major explanatory axis according to their expression levels and their genomic GC content at the synonymous third positions of the codons. The second major explanatory axis differentiates the genes according to their genome type. A comparison of the relative synonymous codon usage between 20 highly- and 20 lowly expressed genes from Bxz1 identified 21 codons, which are statistically over represented in the former group of genes. Further analysis found that the Bxz1- specific tRNA species could recognize 13 out of the 21 over represented synonymous codons, which incorporated 13 amino acid residues preferentially into the highly expressed proteins of Bxz1. In contrast, seven amino acid residues were preferentially incorporated into the lowly expressed proteins by 10 other tRNA species of Bxz1. This analysis predicts for the first time that the Bxz1-specific tRNA species modulates the optimal expression of its proteins during development.

Prussian blue/serum albumin/indocyanine green as a multifunctional nanotheranostic agent for bimodal imaging guided laser mediated combinatorial phototherapy

Sahu, A.,Lee, J.H.,Lee, H.G.,Jeong, Y.Y.,Tae, G. Elsevier Science Publishers 2016 Journal of controlled release Vol.236 No.-

<P>Developing novel nanotheranostic agent using only clinically approved materials is highly desirable and challenging. In this study, we combined three clinically approved materials, Prussian blue (PB), serum albumin (BSA), and indocyanine green (ICG), by a simple and biocompatible method to prepare a multifunctional theranostic PB-BSA-ICG nanoparticle. The multifunctional nanoparticle system could provide dual mode magnetic resonance (MR) and near infrared (NIR) fluorescence imaging as well as combined photothermal and photodynamic (PTT-PDT) therapy in response to a single NIR laser. This nanoparticle showed an excellent stability in physiological solutions and could suppress the photo-instability of ICG. In the absence of light, the nanoparticles showed no cytotoxicity, but significant cell death was induced through combined PTT-PDT effect after irradiation with NIR laser light. A high tumor accumulation and minimal nonspecific uptake by other major organs of PB-BSA-ICG nanoparticle were observed in vivo, analyzed by T-1-weighted MR and NIR fluorescence bimodal imaging in tumor xenograft mice after intravenous injection. The nanoparticles efficiently suppressed the tumor growth through combinatorial phototherapy with no tumor recurrence upon a single NIR laser irradiation. These results demonstrated that PB-BSA-ICG is potentially an interesting nanotheranostic agent for imaging guided cancer therapy by overcoming the limitations of each technology and enhancing the therapeutic efficiency as well as reducing side effects. (C) 2016 Elsevier B.V. All rights reserved.</P>

Low temperature synthesis of silicon quantum dots with plasma chemistry control in dual frequency non-thermal plasmas

Sahu, Bibhuti Bhusan,Yin, Yongyi,Han, Jeon Geon,Shiratani, Masaharu The Royal Society of Chemistry 2016 Physical chemistry chemical physics Vol.18 No.23

<P>The advanced materials process by non-thermal plasmas with a high plasma density allows the synthesis of small-to-big sized Si quantum dots by combining low-temperature deposition with superior crystalline quality in the background of an amorphous hydrogenated silicon nitride matrix. Here, we make quantum dot thin films in a reactive mixture of ammonia/silane/hydrogen utilizing dual-frequency capacitively coupled plasmas with high atomic hydrogen and nitrogen radical densities. Systematic data analysis using different film and plasma characterization tools reveals that the quantum dots with different sizes exhibit size dependent film properties, which are sensitively dependent on plasma characteristics. These films exhibit intense photoluminescence in the visible range with violet to orange colors and with narrow to broad widths (similar to 0.3-0.9 eV). The observed luminescence behavior can come from the quantum confinement effect, quasi-direct band-to-band recombination, and variation of atomic hydrogen and nitrogen radicals in the film growth network. The high luminescence yields in the visible range of the spectrum and size-tunable low-temperature synthesis with plasma and radical control make these quantum dot films good candidates for light emitting applications.</P>

A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches

Sahu Bhanu P.,Baishya Rinku,Hatiboruah Jyoti Lakshmi,Laloo Damiki,Biswas Nikhil 한국약제학회 2022 Journal of Pharmaceutical Investigation Vol.52 No.5

Background Despite tremendous advancements in cancer treatment delivery, we are still far from achieving successful cancer prognosis and cure. The use of new nanocarriers for site-specific delivery of anticancer medicines with lower toxicity has shown promise. However, the successful translation of these works into products remains a challenge. Hence, a thorough examination of the various nanocarrier systems is required, with particular emphasis on the more recent approaches. Area Covered The review discusses how nanocarrier designs have evolved with each generation based on EPR, overexpressed receptors, stimuli-responsive systems, intracellular and extracellular targeting, immunotherapy, and the recent multifunctional theranostic approach, as well as their potential and limitations. The clinical translations of these systems, as well as the issues that have arisen, have been examined, along with potential future opportunities. Newer immunosystems and multifunctional theranostic methods have received special attention. Expert Opinion It has been observed that nanocarrier systems have evolved in three major generations. Despite all of the efforts, clinical success is limited to the first generation of EPR-based passive targeting. Active targeting is mostly limited to the preclinical stage. Tumor heterogeneity and poor delivery to the location remain a key worry and roadblock. Hence, the newer generation nanocarriers need a more multifunctional approach, combining active targeting with immunotherapy and diagnostic contrast agent delivery. Newer theranostic designs with combined effects of chemotherapy, immunotherapy, and other therapies such as photodynamic, photothermal, and photoacoustic need to be worked on. Besides, there is a need of finding new cancer markers, toxicity studies, and scale-up approaches to these nanosystems.

Nitrogen Ion Implantation Effect on Silicon Solar Cells for Surface Passivation

Sahu, Rajkumar,Palei, Srikanta,Choi, Jaeho,Kim, Keunjoo American Scientific Publishers 2018 Journal of nanoelectronics and optoelectronics Vol.13 No.10

Comparison of plasma excitation, ionization, and energy influx in single and dual frequency capacitive discharges

Sahu, B. B.,Han, Jeon G. American Institute of Physics 2016 Physics of plasmas Vol.23 No.12