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Photothermal Therapy of Copper Incorporated Nanomaterials for Biomedicine
Rong Wang,Ziwei Huang,Yunxiao Xiao,Tao Huang,Jie Ming 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00
Studies have reported on the significance of copper incorporated nanomaterials (CINMs) in cancer theranostics and tissue regeneration. Given their unique physicochemical properties and tunable nanostructures, CINMs are used in photothermal therapy (PTT) and photothermal-derived combination therapies. They have the potential to overcome the challenges of unsatisfactory efficacy of conventional therapies in an efficient and non-invasive manner. This review summarizes the recent advances in CINMs-based PTT in biomedicine. First, the classification and structure of CINMs are introduced. CINMs-based PTT combination therapy in tumors and PTT guided by multiple imaging modalities are then reviewed. Various representative designs of CINMs-based PTT in bone, skin and other organs are presented. Furthermore, the biosafety of CINMs is discussed. Finally, this analysis delves into the current challenges that researchers face and offers an optimistic outlook on the prospects of clinical translational research in this field. This review aims at elucidating on the applications of CINMs-based PTT and derived combination therapies in biomedicine to encourage future design and clinical translation.
Huang Chia-Yu,Wu Mei-Yao,Huang Ming-Cheng,Yu Teng-Shun,Yen Hung-Rong 한국한의학연구원 2023 Integrative Medicine Research Vol.12 No.3
Background: The pressure ulcer is a complication from dementia. The aim of this study is to study the association between the developing of pressure ulcers and the use of acupuncture therapy in patients with dementia. Methods: We performed a retrospective 1:1 propensity score-matched cohort study to investigate the association between acupuncture therapy and the risk of pressure ulcers in patients with dementia. Results: A total of 8,994 patients were identified, 237 patients in the acupuncture cohort and 362 patients in the no-acupuncture cohort developed pressure ulcers. A reduced cumulative incidence of pressure ulcers was observed in the acupuncture cohort (P < .001). The association between acupuncture and reducing the incidence of pressure ulcers was not affected by sex, age, residence, income, or comorbidities. The variables of etiologies to cause dementia did not change the final result. In the subgroups analyses, the patients without medication for dementia controlling had significant lower rate of pressure ulcers development when they had accepted acupuncture therapy (log-rank test, P <.001). Conclusion: Our results revealed the association between acupuncture therapy and a reduced incidence of pressure ulcer development in patients with dementia. This finding offers important ideas for further research.
Huang, Rong-Hui,Lu, Ri-Yu,Chen, Wen,Chen, Ji-Rong Korean Meteorological Society 2003 大氣 Vol.13 No.2
Recent advances in the studies on the interaction between Asian monsoon and ENSO cycle are reviewed in this paper. Through the recent studies, the East Asian summer monsoon circulation system and the East Asian climate system have proposed. Moreover, different responses of the (winter and summer) monsoon circulation and summer rainfall anomalies in East Asia to ENSO cycle during its different stages have been understood further. Recently, the studies on the dynamical effect of East Asian monsoon on the thermal variability of the tropical western Pacific and ENSO cycle have been greatly advanced. These studies demonstrated further that ENSO cycle originates from the tropical western Pacific, and pointed out that the dynamical effect of East Asian winter and summer monsoons on ENSO cycle may be through the atmospheric circulation and zonal wind anomalies over the tropical western Pacific, which can excite the oceanic Kelvin wave and Rossby waves in the equatorial Pacific. Besides, the scientific problems in the interaction between Asian monsoon and ENSO cycle, which should be studied further in the near future, are also pointed out in this paper.
Perspective of red imported fire ant (Solenopsis invicta) management in Taiwan
Rong-Nan Huang 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04
The red imported fire ant (RIFA, Solenopsis invicta), an exotic species, detected in Taiwan in 2003 was originally from USA. A program was launched immediately under Bureau of Animal and Plant Health Inspection and Quarantine Council of Agriculture (BAPHIQ) in 2004 for RIFA management. The National Red Imported Fire Ant Control Center (NRIFACC) helps the BAPHIQ to integrate/coordinate the RIFA eradication program which involves every governmental department, however the actual implementation of prevention and control work is the local government. It has made a significant progress in public education, since our general public can recognize RIFA accurately now and succeed to localize RIFA in Northern Taiwan. However, nationwide RIFA eradication is still far from success, the major constraints of the eradication program in Taiwan include (1) RIFA had likely been in Taiwan longer than reported, (2) difficulty to detect incipient infestation, (3) mass reproductive queens that can spread over 10-20 km after nuptial flight, (4) movement control is not easy to perform, (5) man power or company for chemical treatment is not enough, (6) funding is insufficient to allow success, (7) meteorological condition disfavors the control practice. Fortunately, we have developed humidity resistant baits that could enhance the control efficiency of RIFA in humid or wet conditions and resolve the weather constraints of RIFA and other invasive ants control in wet tropical and subtropical habitats. For the success of NRIFACC eradication efforts, participation of all stakeholders would remain a very important strategy in the future. In particular, a centralized team would further facilitate the management of RIFA. Moreover, due to the increasing in international trades and the recent detection of RIFA in Japan and Korea, an international efforts and cooperation on RIFA management is a key issue to control global movements of RIFA.
( Huang Rong Jin ),( Li Ye Ping ),( Kulm Gerald ),( Willson Victor ) 한국수학교육학회 2014 수학교육연구 Vol.18 No.2
In this study, we examined the relationships among years of teaching experience, professional rank, number of courses taken, and knowledge of algebra for teaching (KAT). 338in-service and 376 pre-service secondary mathematics teachers in China completed a KAT questionnaire. Various statistical techniques were employed to examine these relationships. The pre-service participantsteachers performed statistically significantly higher in advanced mathematics knowledge than in-service counterparts. For the in-service teachers, senior teachers had more strong knowledge in school mathematics and teaching mathematics, compared with junior teachers. Yetparticipants’ advanced mathematics knowledge decreased as their professional rank advanced or their teaching experience increased. The number of courses taken is significantly correlated with school mathematics knowledge and advanced mathematics knowledge, but not with teaching mathematics knowledge. The implications of these findings for mathematics teacher education are discussed.
Penetration Processes of Soft Solid Materials by Needle-Free Micro-Injections
( Muh Rong Wang ),( Chun Hsien Chiu ),( Chien Chih Huang ),( Li Jay Cheng ),( Yang Sheng Huang ),( Min Chen ) 한국액체미립화학회 2010 한국액체미립화학회 학술강연회 논문집 Vol.2010 No.-
Penetration characteristics of the single pulse micro-jets into the soft solid materials of gelatin gels and porcine colons are investigated in this paper. The images of penetration processes were taken by IDT high-speed digital camera at the sampling rate of 2500 frames per second. The evolution of the penetration process, penetration depth, volume of infection and penetration rate is investigated. Gelatin gel is a good model material for the observation of the penetration processes because of the translucent property. In vitro penetrations of porcine colons were also tested for the prior study of endoscopic needle-free injection. The penetration test was performed under the single-pulsed mode at injection time of 0.1, 0.25 and 0.5 seconds. The injection pressure was in the range of 50 to 125 bar. The diameter of the injectors, do, is 250 and 300 m. According to the high-speed photos of the gel penetration, the injection processes can be described as four steps: 1. Initial compression period: the elastic compression of the soft solid material at the penetration site and the neighborhood. 2. Material failure period: the jet penetrates inside the gelatin gel including the initial surface crack and growth of the injected volume. 3. Elastic rebounding period: It takes place when the injection is stopped. The injected water starts to be squeezed out of the gelatin gel under the compression of the gelatin gel during the elastic relaxation processes until the final penetration depth and width. 4. Final stable period: the penetration depth and width inside the gelatin gel are fixed afterward. Furthermore, the injection tests on the porcine colon show the penetration into submucosal layer is possible under the injection pressure less than 60 bar with the orifice of 300 m and injection time of 0.1 sec. The injection power is 16 W under this condition. However, higher injection power is needed for the punch through injection of porcine colon. The failure stress of the porcine colon is 1.077 0.333 MPa by the deep penetration test.