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      • 韓國産 脣形(꿀풀)科 植物에 關한 本草學的 硏究

        盧炳圭,金裕鎭,金台睍,宋昊埈,辛民敎 한국전통의학연구소 1999 한국전통의학지 Vol.9 No.1

        A Herbalogical Study in the Plants of Labiatae in Korea. For the purpose of developing Korean Herbgalogy with the plants of Labiatae which grow wild and is planted in korea, the these and writings on herbalogy, from literature of successive generations, have been throughly investigative and the results obtained were as follows: 1. There were totaled to 27 genera and 86 species in Korea and among them medical plants are 24 genera, 59 species, some 68% in total but, the number of species may be added because of the similar plants. 2. According to the oriental names which can be used for medical purpose, the medical plants belonging to the Labiatae family were classified as Herba 29, Radix 4, Fructus 3, Folium 2, Lignum 2, Semen 1 and Flos 1. 3. According to sum of 86 species in Labiatae family, they were classified into Scutellaria genera 10, Salvia genera 6, Ajuga genera 5, Clinopodium genera 5, Elsholtzia genera 5 and Mosla 5. Thus it was noticed that Scutellaria genera was the main kind, some 12% in total. 4. According to the number of species of the original plants about each chinese materia medicals, they were classified into HERBA AGASTACHIS 5 and HERBA AJUGAE, HERBA SCUTELLARIAE, HERBA LYCOPI 3 each. 5. According to nature and flavour of medical plants, they were classified into warmth, heat: 20 each, cold, cool: 16 each, balance 4 and unidentified 2. Thus it was noticed that warmth and heat is the main in nature and flavour medicinal plants. 6. According to the Properties and Principal curative action, they were classified into drugs for clearing up heat and toxin 8, drugs for clearing up heat and dispelling pathogenic heat from blood, drugs for clearing up heat and heatstroke 3 each, drugs for activating the blood and removing blood stasis, drugs which is sudorific and pungent in nature and flavour for dispelling wind and cold in the treatment of exterior symptom complex 4 each. Thus it was noticed that drugs for clearing up heat was the main kind. 7. Comparing to whole medical plants 42 kinds, toxic drugs include minor toxin were 3 kinds, 7% of the whole. Thus toxic drugs were rare. From this result, it was revealed that the plants for medical purpose in Labiatae was 68% of the whole, in which HERBA was mostly abundunt and toxic plants was so rare that it will be used for clinical treatment more easily. It is considered that many experiements and clinical approches must be continued to use Labiatae plants widely.

      • 고속 밀링 주축용 자기베어링 시스템의 디지털 제어기 설계

        노승국,경진호,박종권 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

        The demand of high speed machining is increasing because the high speed cutting provides high efficiency of process, short process time, improved metal removal capacityand better surface finish. Active magnetic bearings allow much high surface speed than conventional ball bearings and therefore greatly suitable for high speed cutting. The automatic control concept of magnetic bearing system provides ability of intelligent control of spindle system to increase accuracy and flexibility by means of adaptive vibration control. This paper describes a design and development of a milling spindle system which includes built-in motor with power 5.5 kW and maximum speed 70,000rpm, HSK-32C tool holer and active magnetic bearing system. Magnetic actuators are designed for satisfying static load condition. The Performances of manufactured spindle system was examined for its static and dynamic stiffness, load capacity, and rotational accuracy. This spindle was run up to 70,000rpm stably, which is 3.5 million DmN.

      • KCI등재
      • 폐경기후 골다공증의 약물요법

        노흥규,송치운,이진홍,안미애,송민호 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Postmenopausal osteoporosis is an enormous public health problem. Estrogens, and various drugs were developed and used for prevention and treatment of postmenopausal bone loss. In this study, We evaluated the effects of cycloprogynova, cyclofenil and ipriflavone on postmenopausal bone loss. Fourty post menopausal women were divided into 3 groups by treatment modalities Cyclofenil group (groupl), Cycloprogynova group(group 2) and Ipriflavone group(group 3). Basal bone mineral densities in all subjects were determined by DEXA(Dual Energy X-ray Absorptiometry) and those were compared with bone mineral densities after medication. The durations of medication in all groups were showed no statistical difference, group 1 11.4 ± 3.4 months, group 2 10.6 ± 3.9 months, group 3 12.9 ± 3.4 months. The patients of group 2 showed significant increase in bone mineral densities and the patients of group 1 and group 3 revealed no significant bone loss on paired T-test. Comparing with rates of bone loss in normal Korean postmenopausal women, the rates of bone loss in all subjects were effectively retarded. The significant bone loss (above longterm intertest coeffcient of variation) was noted in 8 patients out of 23 subjects in group 1, in 9 patietns out of 11 subjects in group 2 and in 2 patients out of 6 subjects in group 3. In conclusion, estrogen/progesteron(Cycloprogynova) replacemnt therapy showed most prominent bone preserving effect and Cyclofenil and Ipriflavone also effectively delays shorterm bone loss in postmenopausal women.

      • SCIESCOPUSKCI등재
      • 通話量 管理시스템의 電算化에 관한 硏究

        윤형로,박규태,김진호 연세대학교 산업기술연구소 1981 논문집 Vol.13 No.2

        In the telecommunication network traffic information is used for improving present utilization by means of efficient operation of switching facilities and for designing economical telephone network by means of forecasting the future trends. Various kinds of software developed and added to the AUTRAX System, which is designed for automatic measurement, to accomplish a complete traffic information systems. For the use of traffic information to design the future telephone network, some mathematical models, which are derived for calculation of point to point traffic estimation and forecasting of future traffic distribution, were studied. Some computer programs for several models were developed and implemented.

      • Incidental Left Ventricular Thrombus Visualized by Cardiac Magnetic Resonance Imaging with a Normal Left Ventricular Systolic Function

        Sang Mi Ro1,Sung Ho Her,Sol Mi Huo,Kuhn Park,Jong Bum Kwon,Dong Jae Lee,Hyun Jin Noh 조선대학교 의학연구원 2015 The Medical Journal of Chosun University Vol.40 No.3

        Left ventricular (LV) thrombi may be caused by various conditions, particularly myocardial infarction. In most cases, LV thrombus occurs in patients with a significantly reduced ejection fraction. A LV thrombus is extremely rare in patients with normal LV function. We report a case of LV thrombus initially detected on transthoracic echocardiography and confirmed using cardiac magnetic resonance imaging in a patient with normal LV wall motion. We highlight the rarity of this condition and the usefulness of cardiac magnetic resonance imaging in the diagnosis of LV thrombus.

      • 사람 갑상선자극호르몬 수용체를 발현하는 Chinese Hamster Ovary(hTSHR-CHO)세포를 이용한 자극형 갑상선자극호르몬 수용체 항체 활성 측정의 임상적 유용성

        한희정,원진호,채수홍,김현진,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

        Detection of thyroid stimulating hormone receptor(TSHR) autoantibodies has clinical value in establishing the diagnosis of Graves ' disease, and in predicting its clinical course with high sensitivity and high specificity. Especially, TBII using radioreceptor assay has been widely used. Recently, for detecting thyroid stimulating antibody(TSAb), a sensitive method using human TSH receptor-transfected Chinese Hamster Ovary(CHO) cells has been developed and clinically used. The aims of this study are to determine the change and discrepancy of 2 TSHR autoantibodics in clinical course and to evaluate the correlation between 2 autoantibodies. We measured TSAb and TBII in 30 newly diagnosed and untreated patients and in 73 previously diagnosed as Graves ' disease and treated with antithyroid drug. Also we compared the changes of the antibodies in clinical course and correlation between 2 antibodies. Thes results are summarized follows. 1. In newly diagnosed patients, all of the 30 patients had positive TBII and/or TSAb. None of them had negative TBII and negative TSAb. And in newly diagnosed patients, mean TBII and mean TSAb values are 46.8% and 361%, respectively. In 73 treated patients mean values are 18. 7% and 196% each other. Therefore, newly diagnosed group has significant greater TBII and TSAb than antithyroid drug-treated group. 2. TBII was significantly different between euthyroid group and thyrotoxic group in antithyroid drug-treated patients, but TSAb was not. 3. TBII was sequentially decreased as increased medication duration, but TSAb was not shown sequential decrease as increased medication duration. 4. There was significant negative correlation between cumulative doses of antithyroid drug and TBII, but no significant correlation between cumulative doses and TSAb. 6. There was significant positive correlation between TBII and TSAb in total patients group and in antithyroid drug medication group, but not in newly diagnosed group. In conclusion, in Graves ' disease patients, detection of TSHR antibodies are clinical values in establishing the diagnosis and prediction of clinical course. A method detecting TSAb using hTSHR-CHO cells should be further studied for standardization of measurement, and for detecting the changes of TSAb in clinical course, long-term follow-up of patients are important.

      • 혈액투석중인 만성신부전 환자에서 골대사 지표로써의 Osteocalcin치

        송치운,이진홍,안미애,윤환중,윤상임,성기양,이강현,송민호,이강욱,신영태,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        Background : Serum osteocalcin is synthesized by osteoblast and has been shown to be sensitive indicator of bone turnover inpatients with various metabolic bone disease. In renal osteodystrophy, serum osteocalcin is elevated due to decreased renal clearance and elevated level of PTH. This study was done to evaluate the usefulness of serum osteocalcin as a marker of bone metabolism and the correlation with other biochemical markers of bone metabolism. Methods : We measured serum osteocalcin, calcium, phosphorus, ALP(alkaline phosphatase) and PTH(parathyroid hormone) in 37 patients with end stage renal disease on hemodialysis. Osteocalcin was determined by radioimmunoassay and PTH was determined by radioimmunometric assay. Results : 1) The mean level of serum osteocalcin in ESRD patients was 233.8± 218.2ng/ml which was significantly higher than that of controls(p<0.0001). 2) The mean level of serum PTH in ESRD patients was 40.5± 43.8pg/ml was significantly higher than that of controls(p<0.005). 3) There was a significant positive correlation between the level of serum PTH, ALP and the level of serum osteocalcin in ESRD patients. 4) By using multiple regression, PTH is most reliable factor that affect to elevated level of serum osteocalcin ( beta coefficient = 0.687, Sig T<0.05). Conclusion : Serum osteocalcin as a marker of bone metabolism in ESRD patients is more useful than other biochemical marker such as serum calcium, phosphorus, ALP and PTH is a most reliable factor that affect to elevated level of serum osteocalin.

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