Magnetocaloric Properties in Ordered Double-perovskite Ba2Fe1−xCrxMoO6 (0 ≤x ≤1)

R. M’nassri,A. Cheikhrouhou 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.6

The magnetocaloric proprieties of Ba2Fe1−xCrxMoO6 (cubic, Fm3m) have been investigated. With the help of the phenomenological model, the temperature dependences of the magnetizationfor Ba2Fe1−xCrxMoO6 (0 ≤ x ≤ 1) in a 1 T magnetic field were simulated. The behavior of thetemperature-dependent magnetocaloric effect was investigated in the vicinity of magnetic phasetransitions. The magnetic entropy change and the specific heat were obtained. The values of themaximum magnetic entropy change, the full width at half maximum, and the relative cooling powerfor a change in the magnetic field of 1 T were calculated. The values and the shapes of −SMand −Cp strongly depended on the Cr concentration. As x was increased, the maximum valuesof −SM and −Cp decreased and the peaks of −SM and −Cp became broader. Themagnetocaloric effect of this material is large and tunable, suggesting a possible technical applicationof the material at moderate magnetic fields at temperatures near room temperature. ForBa2Fe1−xCrxMoO6, the magnetic entropy change was shown to follow a master curve behavior.

상아모세포 분화과정에서 nuclear factor I - C 의 역할

배현숙,김홍중,정문진,박민주,안성민,Gronostajski RM2,박주철 대한구강악안면병리학회 2005 대한구강악안면병리학회지 Vol.29 No.2

Nuclear factor 1 (NFI) was discovered as a protein required for adenovirus DNA replication in vitro, but it is now clear that NFI protein plays an important role in the expression of many cellular genes. NFI-C null mice demonstrated aberrant odontoblast differentiation, abnormal dentin formation, and thus molar lacking roots while other tissues/or gans in the body, including ameloblasts appear to be unaffected and normal. However, little is known about the mechanism of NFI -C function in odontoblast differentiation and dentin formation. In this study, in order to elucidate the molecular mechanisms of odntoblast differentiation, we examined morphological characteristics of the aberrant odontoblast in NFI-C null mice. we also evaluate the expression of dentin sialophosphoprotein (DSPP) and bone sialoprotein (BSP) mRNAs in the MDPC-23 cells by northern analysis after over-expression and inactiγation of NFI -C into mouse MDPC-23 cells Odontoblasts of the NFI-C null mouse were round in shape, lost their polarity, organized as a sheet of cells, and trapped in osteodentin-like mineralized tissue. Abnormal odontoblasts of NFI-C null mouse revealed the absence of an intercellular junctional complex known as the t erminal webs. MDPC-23 cells started to express DSPP mRNA beginning from the postnatal day of 14 and showed a steady increase as differentiating into odontoblasts. Over-expression of NFI -C increased the expression of DSPP mRNA. Inactivation of NFI - C induced BSP mRNA expression. These results suggest that NFI-C plays an important role in odontoblast differentiation in a cell-type specific manner and thus in dentin formation

Toxicity studies on Trigonella foenum-graecum L. seeds used in spices and as a traditional remedy for diabetes

RM Al-Ashban,RR Abou-Shaaban,AH Shah 경희대학교 융합한의과학연구소 2010 Oriental Pharmacy and Experimental Medicine Vol.10 No.2

Acute (24 h) and chronic (90 days) oral toxicity studies on the ethanol extract of Trigonella foenum-graecum Leguminosae (L.) seeds were carried out. Acute dosages were 0.5, 1.0 and 3 g/kg while chronic dosage was 100 mg/kg per day of the extract. All morphological, biochemical, haematological and spermatogenic changes, in addition to mortality, body weight changes and any change in vital organs were recorded. Histopathological investigations were done on vital organs. Growth arrest in the treated animals was observed. The treated mice gained no significant weight during chronic treatment while there was a significant gain in body weight of the control group mice. Biochemical studies revealed a significant decrease in blood sugar levels of fenugreek treatment groups while haematological parameters remained comparable to the control. In the treatment,male group there was a significant decrease in weight of testes as compared to the control. There was a marginal weight gain in kidney weight of mice after chronic treatment as compared to the control. Fenugreek chronic treatment caused a highly significant spermatotoxic effects in male mice.

내원환자를 이용한 꽃가루 알레르기 위험도 연구

Hye-Rm Lee,Kyu Rang Kim,Young-Jean Choi,Jae-Won Oh 한국기상학회 2011 한국기상학회 학술대회 논문집 Vol.2011 No.10-1

In vitro response of rat microglia and human polymorphonuclear cells (PMN) to immunoactive compounds

Lombardi, Valter RM,Eetcheverria, Ignacio,Fernandez-Novoa, Lucia,Diaz, Joaquin,Seoane, Silvia,Cacabelos, Ramon Kyung Hee Oriental Medicine Research Center 2005 Oriental pharmacy and experimental medicine Vol.5 No.3

Although the field of study in immune enhancing compounds is relatively new, natural products from plants represent a rich and promising source of novel molecules with immunomodulating properties, Microglial cells, the main immune effector cells of the brain, usually display a ramified morphology and low expression levels of immunologically relevant antigens such as MHC class I and class II. Since any compound which participates in activation of phagocytic cells contributes to the production of potentially toxic factors, the search for convenient in vitro test-systems and study of mechanisms of action of these agents are of great interest. Human blood polymorphonuclear (PMN) cells and primary microglial cells isolated from Sprague-Dawley rats were used as cellular screening tests for study of phagocytosis-stimulating action of immunomodulating agents. Numbers of phagocytic activity were evaluated by the phagocyte ingestion of yeast cells and NO-synthase activity, nitrite production, and nitroblue tetrazolium test were determined after phagocyte stimulation. It was possible to demonstrate that indexes of phagocytic activity can be used as quantitative indicators for measurement immunomodulating activity. As a positive control, Zymosan A-induced phagocytosis in both PMN cells and primary microglial cells was used. $IFN-{\gamma}$ (0.1 -1 U/ml) stimulated phagocytosis in PMN cells 1.2 times after 2 - 3 h incubation, although at higher concentrations (10 - 100 U/ml) it strongly inhibited phagocytosis. In a similar way, at higher concentrations, $IFN-{\gamma}$ (100 - 500 U/ml) suppressed phagocytosis in zymosan-A stimulated microglial cells. When Polypodium leucotomus, cambricum and vulgare extracts were tested alone, increased levels of phagocytosis were observed in PMN. In addition, microglial cells showed both increased phagocytosis and MHC class-II antigen expressions. Surprisingly, when PMN and microglia were treated with a combination of Polypodium and $IFN-{\gamma}$, phagocytosis was not inhibited. We did not find changes in NO-synthase activity and nitrite production in both microglia and PMN cells activated by different immunomodulating agents. These results indicate that primary microglial cell cultures as well as human PMN cells can provide reproducible quantitative results in screening phagocytic activity of different immunoactive compounds. Furthermore, both inhibitory or activation mechanisms might be studied using these in vitro experimental approaches.

loT Enabled Smart Waste Bin with Real Time Monitoring for efGcient waste management in Metropolitan Cities

Manju Mohan,RM. Kuppan Chetty,Vijayram Sriram,Mohd. Azeem,P. Vishal,G. Pranav ASCONS 2019 IJASC Vol.1 No.3

Background/Objectives: Waste bins are part of our lives for decades and mostly its condition are overflowing due to improper waste dumping, collection and management, which leads in foul smell and unhygienic condition, thus inherently results in environment pollution. Methods/Statistical analysis: Therefore, in this paper, design of a Waste Bin with real time monitoring is presented and a smart waste management system is proposed using the recent technical advancements of automation and Internet of Things (IoT). Findings: The capacitance sensor in the bin continuously monitors the level of the bin in real time and communicates to the central cloud where the bins are connected. Ultrasonic sensor is used to open and close the lid of the bin whenever the persons are nearby the bin. Such smart bins are connected to the cloud, where the bin status are communicated, recorded and monitored by the local bodies through and android app or a centralized server. Improvements/Applications: Thus the designed smart bin and proposed waste management system have better level of smartness compared to existing ones in metropolitan cities in a centralized manner.

Bee venom induces apoptosis through caspase-3 activation in synovial fibroblasts of patients with rheumatoid arthritis

Hong, Seung-Jae,Rm, Gyu-Sung,Yang, Hyung In,Yin, Chang Shik,Koh, Hyeong Gyun,Jang, Mi-Hyeon,Kim, Chang-Ju,Choe, Bong-Keun,Chung, Joo-Ho KYUNG HEE UNIVERSITY MEDICAL CENTER 2006 고황의학상 수상논문집 Vol.21-22 No.-

Bee venom (BV) has been used traditionally for the control of pain and inflammation in various chronic inflammatory diseases, including rheumatoid arthritis (RA) in Oriental medicine. However, it is still unclear how BV exerts its beneficial effects on the clinical course of RA patients. To investigate the effect of BV on the treatment of rheumatoid synovitis, we examined the inhibition of cell growth and induction of apoptosis in human rheumatoid synovial fibroblasts. Rheumatoid synovial fibroblasts were surgically obtained from patients with RA. Cell proliferation and viability were assessed by the 3-(4.5- dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The apoptosis of synovial cells treated with 10 ㎍/ml BV for 24h was identified by 4,6-diamidino-2-phenylindole (DAPI) staining, terminal deoxynucleotidyl transferase-mediated dUTP nick end labelling (TUNEL) assay, DNA fragmentation assay, RT-PCR, and Western blot analysis. It was demonstrated that rheumatoid synovial cells treated with 10 ㎍/ml BV for 24h exhibited apoptotic features and fragmentation of DNA. In addition. BV induces apoptosis in rheumatoid synovial cells through a decrease in BCL2 expression and an increase in BAX and caspase-3 (CASP3) expression. It is suggested that BV inhibits the proliferation of rheumatoid synovial cells through induction of apoptosis by CASP3 activation.

Ship's Collision Avoidance Support System Using Fuzzy-CBR

Park, Gyei-Kark,Benedictos John Leslie RM. Korean Institute of Intelligent Systems 2006 한국지능시스템학회논문지 Vol.16 No.5

Ship's collision avoidance is a skill that masters of merchant marine vessels have acquired through years of experience and that makes them feel at ease to guide their ship out from danger quickly compared to inexperienced officers. Case based reasoning (CBR) uses the same technique in solving tasks that needs reference from variety of situations. CBR can render decision-making easier by retrieving past solutions from situations that are similar to the one at hand and make necessary adjustments in order to adapt them. In this paper, we propose to utilize the advantages of CBR in a support system for ship's collision avoidance while using fuzzy algorithm for its retrieval of similar navigational situations, stored in the casebase, thus avoiding the cumbersome tasks of creating a new solution each time a new situation is encountered. There will be two levels within the Fuzzy-CBR. The first level will identify the dangerous ships and infer the new case. The second level will retrieve cases from casebase and adapt the solution to solve for the output. While CBR's accuracy depends on the efficient retrieval of possible solutions to be adapted from stored cases, fuzzy algorithm will improve the effectiveness of solving the similarity to a new case at hand.

Aortic Root Honeycomb: A Rare Cardiac Surgery Complication

Joana Laranjeira Correia,Vanda Devesa Neto,Gonçalo RM Ferreira,Davide Moreira,Rogério Teixeira 한국심초음파학회 2023 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.31 No.2

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Building a Conceptual Model Using Ontology for the Efficient Retrieval of Cases from Fuzzy-CBR of Collision Avoidance Support System

Gyei-Kark Park(박계각),John Leslie RM Benedictos,Sung Chul Shin(신성철),Nam Kyun Im(임남균),Mira Yi(이미라) 한국지능시스템학회 2007 한국지능시스템학회 학술발표 논문집 Vol.17 No.1

We have proposed Fuzzy-CBR to find a solution from past knowledge retrieved from the database and adapted to a new situation. However, ontology is needed in identifying concepts, relations and instances that are involved in a situation in order to improve and facilitate the efficient retrieval of similar cases from the CBR database. This paper proposes the way to apply ontology for identifying the concepts involved in a new case, used as inputs, for a ship collision avoidance support system and in solving for similarity through document articulation and abstraction levels. These ontologies will be used to build a conceptual model of a maneuvering situation..