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- 저자 : Qingcheng Liu (검색결과 2 건)
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Chenglei Liu,Yan Xi,Mei Li,Qiong Jiao,Huizhen Zhang,Qingcheng Yang,Weiwu Yao 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.5
Objective: To determine whether diffusion kurtosis imaging (DKI) is effective in monitoring tumor response to neoadjuvant chemotherapy in patients with osteosarcoma. Materials and Methods: Twenty-nine osteosarcoma patients (20 men and 9 women; mean age, 17.6 ± 7.8 years) who had undergone magnetic resonance imaging (MRI) and DKI before and after neoadjuvant chemotherapy were included. Tumor volume, apparent diffusion coefficient (ADC), mean diffusivity (MD), mean kurtosis (MK), and change ratio (ΔX) between preand post-treatment were calculated. Based on histologic response, the patients were divided into those with good response (≥ 90% necrosis, n = 12) and those with poor response (< 90% necrosis, n = 17). Several MRI parameters between the groups were compared using Student’s t test. The correlation between image indexes and tumor necrosis was determined using Pearson’s correlation, and diagnostic performance was compared using receiver operating characteristic curves. Results: In good responders, MDpost, ADCpost, and MKpost values were significantly higher than in poor responders (p < 0.001, p < 0.001, and p = 0.042, respectively). The ΔMD and ΔADC were also significantly higher in good responders than in poor responders (p < 0.001 and p = 0.01, respectively). However, no significant difference was observed in ΔMK (p = 0.092). MDpost and ΔMD showed high correlations with tumor necrosis rate (r = 0.669 and r = 0.622, respectively), and MDpost had higher diagnostic performance than ADCpost (p = 0.037) and MKpost (p = 0.011). Similarly, ΔMD also showed higher diagnostic performance than ΔADC (p = 0.033) and ΔMK (p = 0.037). Conclusion: MD is a promising biomarker for monitoring tumor response to preoperative chemotherapy in patients with osteosarcoma.
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Lixia Zou,Qingcheng Liu,Qiong Xu,Guanjie Mi 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.5
Mesostructured tungstic acid was prepared from Na_2WO_4 with protonated cation-exchange using a surfactant cetyltrimethyl ammonium bromine (CTAB) as the structure-directing agent under microwave radiation. The surfactant was removed by high-temperature calcination, microwave radiation extraction and Soxhlet extraction, respectively. The effects of these methods for removal of the surfactant were investigated in detail. XRD, TEM, FT-IR and UV-Vis were employed to characterize the mesostructured materials. The results showed that the microwave extraction and Soxhlet extraction were favorable to the synthesis of mesostructured tungstic oxide. Mesoporous structure was destroyed as the calcining temperature rising to 823 K. The mesoporous structure of WO_3 prepared by microwave radiation extraction had an average pore diameter of 3.4 nm and specific surface area of 120.46m^2·g^(−1). And also, the mesoporous materials WO_3 doping with Bi_2O_3 displayed much higher photocatalytic activity than commercial Degussa P25 TiO_2under visible light and UV irradiation.
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