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Qing-Li Yang,Ji-Qing Shen,Yan Xue,Xiao-Bing Cheng,Zhi-Hua Jiang,Yi-Chao Yang,Ying-Dan Chen,Xiao-Nong Zhou 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.6
The nitric oxide (NO) formation and intrinsic nitrosation may be involved in the possible mechanisms of liver fluke-associated carcinogenesis. We still do not know much about the responses of inducible NO synthase (iNOS) induced by Clonorchis sinensis infection. This study was conducted to explore the pathological lesions and iNOS expressions in the liver of mice with different infection intensity levels of C. sinensis. Extensive periductal inflammatory cell infiltration, bile duct hyperplasia, and fibrosis were commonly observed during the infection. The different pathological responses in liver tissues strongly correlated with the infection intensity of C. sinensis. Massive acute spotty necrosis occurred in the liver parenchyma after a severe infection. The iNOS activity in liver tissues increased, and iNOS-expressing cells with morphological differences were observed after a moderate or severe infection. The iNOS-expressing cells in liver tissues had multiple origins.
Qing Zhong Li,Qing Xian Huang,Shu Cui Li,Mei Zi Yang,Bin Rao 대한생리학회-대한약리학회 2012 The Korean Journal of Physiology & Pharmacology Vol.15 No.5
A simple, sensitive and reproducible high-performance liquid chromatography (HPLC) method has been validated for determining concentrations of glutamate, glycine, and alanine in human plasma. Proteins in plasma were precipitated with perchloric acid, followed by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC). Simultaneous analysis of glutamate, glycine, and alanine is achieved using reversed-phase HPLC conditions and ultraviolet detection. Excellent linearity was observed for these three amino acids over their concentration ranges with correlation coefficients (r)>0.999. The intra- and inter-day precision were below 10%. This method utilizes quality control samples and demonstrates excellent plasma recovery and accuracy. The developed method has been successfully applied to measure plasma glutamate, glycine, and alanine in twenty volunteers.
A Data Placement Algorithm for Data Intensive Applications in Cloud
Qing Zhao,Congcong Xiong,Kunyu Zhang,Yang Yue,Jucheng Yang 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.2
Data layout is an important issue which aims at reducing data movements among data centers to improve the efficiency of the entire cloud system. This paper proposes a data-intensive application oriented data layout algorithm. It is based on hierarchical data correlation clustering and the PSO algorithm. The datasets with fixed location have been considered, and both the offline strategy and the online strategy for data layout have been given. As this proposed strategy is aimed at reducing the global amount of data transmissions, and the special permission of the datasets has been introduced, the cost of data transmission can be measured more reasonable. Simulation results show that compared with two classical strategies, our algorithm can reduce the amount of data transmission more effectively.
A practical coherency model for spatially varying ground motions
Yang, Qing-Shan,Chen, Ying-Jun Techno-Press 2000 Structural Engineering and Mechanics, An Int'l Jou Vol.9 No.2
Based on the discussion about some empirical coherency models resulted from earthquake-induced ground motion recordings at the SMART-1 array in Taiwan, and a heuristic model of the coherency function from elementary notions of stationary random process theory and a few simplifying assumptions regarding the propagation of seismic waves, a practical coherency model for spatially varying ground motions, which can be applied in aseismic analysis and design, is proposed, and the regressive coefficients are obtained using least-square fitting technique from the above recordings.
Increased accumulation of anthocyanins in transgenic potato tubers by overexpressing the 3GT gene
Qing Wei,Qing Yang,Quan-Yi Wang,Zhi-Hang Feng,Bing Wang,Yun-Feng Zhang 한국식물생명공학회 2012 Plant biotechnology reports Vol.6 No.1
In order to explore a biotechnological method for improving potato tuber color and creating plants with increased anthocyanin contents, a potato UDP-glucose: flavonoid-3-O-glucosyltransferase (3GT) gene was inserted behind the GBSSI promoter of pBin19, and this construct was introduced into Solanum tuberosum L. cultivar De´sire´e plants by Agrobacterium-mediated transformation. Six independent transgenic lines overexpressing the 3GT gene were identified by PCR and Southern blot analysis from 18 kanamycin-resistant plants. Due to the expression of 3GT gene, the tuber color and the anthocyanin content were enhanced noticeably in the transgenic plants compared to the wild-type control plants. This result suggests that the 3GT gene can potentially be used to improve potato color and enhance levels of antioxidants in the diet.
Yang Shang-Yang,Li Shu-Cai,Xue Yi-Guo,Zhang Qing-Song 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10
Triaxial compression tests had been performed to determine the properties of the surrounding rock. The displacement and stress of surrounding rock had been analyzed according to Silin 2 at Yungui railway under three kinds of conditions: the initial state, excavation without supporting , and supporting after excavation. Plane strain FEM was established to analyze the stability of the surrounding rock. Contrasted the monitor measuring data, the results showed that the most unfavorable position in the tunnel was found at the ridge side of the arch, and the implementation of support afforded to ensure the stability of surrounding rock, and the design of the early support approach had the ability to meet the safety requirements. The results had certain significance for understanding the mechanical behavior of shallow tunnel in unsymmetrical strata. tunnel, mechanical behaviour, numerical simulation, deformation, stability.
Effect of Channel Curvature for Jet Impinging on Blade Leading Edge
Qing-Yang Zhao,Eui Yeop Jung,Seok Min Choi,Hyung Hee Cho 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.12
The characteristics of fluid flow and heat transfer affected by the curvature variation in a jet impinged leading edge channel have been investigated numerically using three-dimensional Reynolds-averaged Navier-Stokes analysis via shear stress transport turbulence model and γ - Re<SUB>θ</SUB> transitional turbulence model. A constant heat flux condition has been applied on the leading edge surface. Jet to leading edge surface distance is constant as three times of jet diameter. The leading edge curved surface curvature is set as variables by the reason of multiple shape of real turbine blade. Results presented in this study include contour of Nusselt number, velocity vector and local Nusselt number distribution along the central line on the leading edge surface. Based on the data above, the average Nusselt number, stagnation Nusselt number along the central line of leading edge and average pressure supplied on each jet are compared between each case. The varied leading edge curved surfaces change the cross flow intensity which influences the impinging jet flow direction. As a result of the phenomenon of jet flow direction change, the heat transfer on the leading edge is influenced significantly. Result indicates that with the decrease of leading edge curved surface diameter, the cross flow effect improves and heat transfer uniformity decreases. In the case of small diameter leading edge, the average heat transfer decrease and the Nusselt value decreases along the streamwise direction due to the crossflow from upstream jet flow. Besides the heat transfer uniformity, the thermal performance comparison is also investigated in this study.
Design and implementation of a SHM system for a heritage timber building
Qing-shan Yang,Juan Wang,Sunjoong Kim,Huihui Chen,Billie F. Spencer Jr 국제구조공학회 2022 Smart Structures and Systems, An International Jou Vol.29 No.4
Heritage timber structures represent the history and culture of a nation. These structures have been inherited from previous generations; however, they inevitably exhibit deterioration over time, potentially leading to structural deficiencies. Structural Health Monitoring (SHM) offers the potential to assess operational anomalies, deterioration, and damage through processing and analysis of data collected from transducers and sensors mounted on the structure. This paper reports on the design and implementation of a long-term SHM system on the Feiyun Wooden Pavilion in China, a three-story timber building built more than 500 years ago. The principles and features of the design and implementation of SHM systems for heritage timber buildings are systematically discussed. In total, 104 sensors of 6 different types are deployed on the structure to monitor the environmental effects and structural responses, including air temperature and humidity, wind speed and direction, structural temperatures, strain, inclination, and acceleration. In addition, integrated data acquisition and transmission subsystem using a newly developed software platform are implemented. Selected preliminary statistical and correlation analysis using one year of monitoring data are presented to demonstrate the condition assessment capability of the system based on the monitoring data.