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He, Y.,Kim, H.,Ryu, T.,Kang, Y.,Kim, J.A.,Kim, B.H.,Lee, J.H.,Kang, K.,Lu, Q.,Kim, K. North-Holland Pub ; Elsevier Science Ltd 2013 FEBS letters Vol.587 No.2
This study revealed that CWR22Rv-1 cells overexpressing δ-catenin display bigger tumor formation and higher angiogenic potentials than their matched control cells in the CAM assay. In addition, δ-catenin overexpression in CWR22Rv-1 cells results in increased hypoxia-inducible factor 1-alpha (HIF-1α and vascular endothelial growth factor (VEGF) expression. Furthermore, δ-catenin overexpression was found to enhance nuclear distribution of both β-catenin and HIF-1α in hypoxic condition, which is diminished by knockdown of δ-catenin. Our current study adds novel evidence regarding contribution of δ-catenin to the progression of prostate cancer.
X. K. Shang,S. Pan,Q. W. Guan,B. B. He 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.12
The present work focuses on the mechanical behavior of single austenite grain with different orientations in a twinninginduced plasticity (TWIP) steel by nanoindentation test. Deformation twins can be found in [0 0 1]-orientated grains afternanoindentation, while they are absent in grains with [1 1 1] orientation. This inconformity can be ascribed to a largerSchmid factor for leading partial dislocations compared to trailing partial dislocations on the primary slip system in [0 01]-orientated grains during compression. Different from deformation twins, high-density dislocations can be found in both[0 0 1] and [1 1 1]-orientated grains after nanoindentation. The present work suggests that the density of deformation twinscan be enhanced by controlling crystal orientation through texture engineering or by deformation along different directionssuch as cross-rolling.
Hao, L.,He, Y.Q.,Wang, Na,Chen, Z.H.,Chen, Z.G.,Yan, H.G.,Xu, Z.K. The Korean Society for Composite Materials 2009 Advanced composite materials Vol.18 No.4
The thermal stability and elevated temperature mechanical properties of $SiC_P$/Al-11.7Fe-1.3V-1.7Si (Al-11.7Fe-1.3V-1.7Si reinforced with SiC particulates) composites sheets prepared by spray deposition (SD) $\rightarrow$ hot pressing $\rightarrow$ rolling process were investigated. The experimental results showed that the composite possessed high ${\sigma}_b$ (elevated temperature tensile strength), for instance, ${\sigma}_b$ was 315.8 MPa, which was tested at $315^{\circ}C$, meanwhile the figure was 232.6 MPa tested at $400^{\circ}C$, and the elongations were 2.5% and 1.4%, respectively. Furthermore, the composite sheets exhibited excellent thermal stability: the hardness showed no significant decline after annealing at $550^{\circ}C$ for 200 h or at $600^{\circ}C$ for 10 h. The good elevated temperature mechanical properties and excellent thermal stability should mainly be attributed to the formation of spherical ${\alpha}-Al_{12}(Fe,\;V)_3Si$ dispersed phase particulates in the aluminum matrix. Furthermore, the addition of SiC particles into the alloy is another important factor, which the following properties are responsible for. The resultant Si of the reaction between Al matrix and SiC particles diffused into Al matrix can stabilize ${\alpha}-Al_{12}(Fe,\;V)_3Si$ dispersed phase; in addition, the interface (Si layer) improved the wettability of Al/$SiC_P$, hence, elevated the bonding between them. Furthermore, the fine $Al_4C_3$ phase also strengthened the matrix as a dispersion-strengthened phase. Meanwhile, load is transferred from Al matrix to SiC particles, which increased the cooling rate of the melt droplets and improved the solution strengthening and dispersion strengthening.
Shear Thickening Polishing of Black Lithium Tantalite Substrate
B. H. Lyu,Q. Shao,W. Hang,S. H. Chen,Q. K. He,J. L. Yuan 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.9
To achieve high efficiency in the polishing process to obtain a high surface quality of black LT substrate (a kind of soft brittle material), shear thickening polishing (STP), which is a “gentle” finishing process developed in recent years, was employed in this study. The influence of three key parameters in the STP process including polishing speed, diamond abrasive size and diamond abrasive concentration were analyzed. To investigate the potential mechanical effect of the nanometre abrasive, nano-SiO 2 abrasive particles were added in the slurry, and the concentration of SiO 2 abrasive was also taken as a factor. Taguchi method was utilized to evaluate the influence of the four factors and optimize the polishing conditions. The surface roughness (Ra/Rz) was used as the evaluation index, and the optimized polishing conditions were verified through experiments. Diamond abrasive size has the most significant effect on Ra/Rz, followed by diamond abrasive concentration and then SiO 2 concentration, as the polishing speed has been selected and limited in a small variation rang according to the previous study. Based on the S/N average response analysis, the surface quality is the best under the conditions with 8000# diamond abrasive, 5 wt% diamond abrasive concentration, 90 rpm polishing speed and 10 wt% SiO 2 concentration. After 4 min polishing, the surface roughness Ra/Rz is reduced rapidly from 200.5/1374.6 to 4.2/22.1 nm without embedded abrasive particles on the surface of the black LT substrate. It also shows that the mechanical effect plays a dominant role in the material removal. A certain amount (10 wt% in this study) of nano-SiO 2 can reduce friction between solid colloidal and workpiece, and helps to improve surface quality.
SYNTHESIS OF POLYBENZONITRILE WITH ULTRAFAST OPTICAL KERR EFFECT
Zhao, X.Y,Xu, Q,He, Y.K,Chen, H.Y,Wang, C.F,Ai, X.C,Xia, Z.J,Zou, Y.H 한국재료학회 1995 Fabrication and Characterization of Advanced Mater Vol.1 No.3
Plasma polymerization of benzonitrile was carried out with RF glow discharge system. The polymer was characterized by FT-IR, UV-VIS, and Elemental Analysis. the molecular weitht was determined by vapor pressure osmometer. for the first time the nonresonant optical Kerr effect(OKE) of plasma polymerized benzonitrile was measured, and a power law dependence of ${\gamma}_{1111}$ on average polymerization degree was discussed. An ultrafast response was also observed.
Experimental test on bridge jointed twin-towered buildings to stochastic wind loads
Ni, Z.H.,He, C.K.,Xie, Z.N.,Shi, B.Q.,Chen, D.J. Techno-Press 2001 Wind and Structures, An International Journal (WAS Vol.4 No.1
This paper presents results of a study on wind loads and wind induced dynamic response of bridge jointed twin-towered buildings. Utilizing the high-frequency force balance technique, the drag and moment coefficients measured in wind tunnel tests, and the maximum acceleration rms values on the top floor of towers, are analyzed to examine the influence of building's plan shapes and of intervals between towers. The alongwind, acrosswind and torsional modal force spectra are investigated for generic bridge jointed twin-towered building models which cover twin squares, twin rhombuses, twin triangles, twin triangles with sharp corners cut off, twin rectangles and individual rectangle with the same outline aspect ratio as the twin rectangles. The analysis of the statistical correlation among three components of the aerodynamic force corroborated that the correlation between acrosswind and torsional forces is significant for bridge jointed twin-towered buildings.
Characterization of three- and four-point bending properties of porous metal fiber sintered sheet
Zhou, W.,Wang, Q.,Ling, W.,He, L.,Tang, Y.,Wu, F.,Liao, J.,Hui, K.S.,Hui, K.N. Scientific and Technical Press ; Elsevier Science 2014 MATERIALS AND DESIGN Vol.56 No.-
A novel porous metal fiber sintered sheet (PMFSS) with high porosity was fabricated by the solid-state sintering method of copper fibers. In this study, both three- and four-point bending setup were established to characterize the bending properties of PMFSS. Similar three stages in the three- and four-point bending fracture process were observed for the PMFSS with 80% porosity sintered at 900<SUP>o</SUP>C for 60min. Comparing with the three-point bending, it is found that much smaller bending force was obtained in the four-point bending test under the same displacement conditions. Moreover, the porosity and sintering parameters were also varied to investigate the influence on the bending properties of PMFSS. Both three- and four-point bending strength were found to be decreased with increasing porosity ranging from 70% to 90%. Higher sintering temperature produced higher bending strength for the PMFSS sintered in the temperature range of 700-1000<SUP>o</SUP>C. Besides, the extension of holding time also could slightly affect the bending strength.
R&D Status of High-current Accelerators at IFP
J. J. Deng,J. S. Shi,W. P. Xie,L. W. Zhang,K. Z. Zhang,S. P. Feng,J. Li,M. Wang,Y. He,L. S. Xia,Z. Y. Dai,H. T. Li,L. Wen,S. F. Chen,X. Li,Q. G. Lai,M. H. Xia,Y. C. Guan,S. Y. Song,L. Chen 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.61
High-current accelerators have many important applications in Z-pinches, high-power microwaves, and free electron lasers, imploding liners and radiography and so on. Research activities on Zpinches, imploding liners, radiography at the Institute of Fluid Physics (IFP) are introduced. Several main high-current accelerators developed and being developed at IFP are described, such as the Linear Induction Accelerator X-Ray Facility Upgrade (LIAXFU, 12 MeV, 2.5 kA, 90 ns), the Dragon-I linear induction accelerator (20 MeV, 2.5 kA, 60 ns), and the Primary Test Stand for Z-pinch (PTS, 10 MA, 120 ns). The design of Dragon-II linear induction accelerator (20 MeV, 2.5 kA, 3 × 60 ns) to be built will be presented briefly.