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Taehoon Kim,Dong Min Kim,Pratas, Nuno,Popovski, Petar,Dan Keun Sung IEEE 2017 IEEE communications letters Vol.21 No.10
<P>We propose an enhanced access reservation protocol (ARP) with a partial preamble transmission mechanism for the narrow band Internet of Things (NB-IoT) systems. The proposed ARP can enhance the ARP performance by mitigating the occurrence of preamble collisions, while being compatible with the conventional NB-IoT ARP. We provide an analytical model that captures the performance of the proposed ARP in terms of false alarm, misdetection, and collision probabilities. Moreover, we investigate a tradeoff between the misdetection and the collision probabilities, and optimize the proposed ARP according to the system loads. The results show that the proposed ARP outperforms the conventional NB-IoT ARP, in particular, at heavier system loads.</P>
Nuno Trovão,Joana Prata,Orlando VonDoellinger,Susana Santos,Mário Barbosa,Rui Coelho 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.3
ObjectiveaaSchizophrenia is a disabling disorder of unknown aetiology, lacking definite diagnostic method and cure. A reliable biological marker of schizophrenia is highly demanded, for which traceable immune mediators in blood could be promising candidates. We aimed to gather the best findings of neuroinflammatory markers for first-episode psychosis (FEP). MethodsaaWe performed an extensive narrative review of online literature on inflammation-related markers found in human FEP patients only. ResultsaaChanges to cytokine levels have been increasingly reported in schizophrenia. The peripheral levels of IL-1 (or its receptor antagonist), soluble IL-2 receptor, IL-4, IL-6, IL-8, and TNF-α have been frequently reported as increased in FEP, in a suggestive continuum from high-risk stages for psychosis. Microglia and astrocytes establish the link between this immune signalling and the synthesis of noxious tryptophan catabolism products, that cause structural damage and directly hamper normal neurotransmission. Amongst these, only 3-hydroxykynurenine has been consistently described in the blood of FEP patients. ConclusionaaPeripheral molecules stemming from brain inflammation might provide insightful biomarkers of schizophrenia, as early as FEP or even prodromal phases, although more time- and clinically-adjusted studies are essential for their validation.