http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Peter J. Butler (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Lipid Bilayer Control of Nascent Adhesion Formation
Peter J. Butler,Seoyoung Son 대한의용생체공학회 2015 Biomedical Engineering Letters (BMEL) Vol.5 No.3
The adhesion of cells to an extracellular matrix is a dynamicprocess involving structural and signaling proteins, that, inturn, regulate key cellular processes, including migration,gene expression, differentiation and signaling. Integrins playimportant roles as primary adhesion receptors, and integrinmediatedcell adhesion sites can be differentiated, based onsize and location, into nascent adhesions, focal complexes,focal adhesions, and fibrillar adhesions. The formation ofnascent adhesions to a surface requires the bending of themembrane toward a surface, diffusion of integrins to the areaof close contact, and molecular adhesion. Each of theseprocesses is sensitive to the lipid make up of the membrane. Therefore, the lipid bilayer may exert significant control overthe dynamics of nascent adhesion formation. In this review,we consider the structure and components of cellularadhesions and lipid bilayers. We then review membraneproperties of bending rigidity, viscosity, and thickness thatare thought to have a central role in the formation of nascentcell adhesions via membrane curvature, redistribution ofintegrins, and bond formation.
-
Assessing the Nano-Dynamics of the Cell Surface
Bae, Chil-Man,Park, Ik-Keun,Butler, Peter J. The Korean Society for Nondestructive Testing 2012 한국비파괴검사학회지 Vol.32 No.3
It is important to know the mechanism of cell membrane fluctuation because it can be readout for the nanomechanical interaction between cytoskeleton and plasma membrane. Traditional techniques, however, have drawbacks such as probe contact with the cell surface, complicate analysis, and limit spatial and temporal resolution. In this study, we developed a new system for non-contact measurement of nano-scale localized-cell surface dynamics using modified-scanning ion-conductance microscopy. With 2 nm resolution, we determined that endothelial cells have local membrane fluctuations of ~20 nm, actin depolymerization causes increase in fluctuation amplitude, and ATP depletion abolishes all membrane fluctuations.
-
Assessing the Nano-Dynamics of the Cell Surface
Chilman Bae,Ik-Keun Park,Peter J. Butler 한국비파괴검사학회 2012 한국비파괴검사학회지 Vol.32 No.3
It is important to know the mechanism of cell membrane fluctuation because it can be readout for the nanomechanical interaction between cytoskeleton and plasma membrane. Traditional techniques, however, have drawbacks such as probe contact with the cell surface, complicate analysis, and limit spatial and temporal resolution. In this study, we developed a new system for non-contact measurement of nano-scale localized-cell surface dynamics using modified-scanning ion-conductance microscopy. With 2 nm resolution, we determined that endothelial cells have local membrane fluctuations of ~20 nm, actin depolymerization causes increase in fluctuation amplitude, and ATP depletion abolishes all membrane fluctuations.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
