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Interleukin-17A production in Riemerella anatipestifer infection is independent to IL-23
Flores Rochelle(Flores Rochelle ),Fernandez Cherry(Fernandez Cherry ),Afrin Fahmida(Afrin Fahmida ),Cammayo Paula Leona(Cammayo Paula Leona ),Roy Anindita(Roy Anindita ),Min Wongi(Min Wongi ) 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-
Anticoccidial Activity of Berberine against Eimeria-Infected Chickens
Binh Thanh Nguyen,Rochelle Alipio Flores,Paula Leona Taymen Cammayo,Suk Kim,Woo Hyun Kim,Wongi Min 대한기생충학열대의학회 2021 The Korean Journal of Parasitology Vol.59 No.4
Avian coccidiosis has a major economic impact on the poultry industry, it is caused by 7 species of Eimeria, and has been primarily controlled using chemotherapeutic agents. Due to the emergence of drug-resistant strains, alternative control strategies are needed. We assessed anticoccidial effects of berberine-based diets in broiler chickens following oral infection with 5 Eimeria species (E. acervulina, E. maxima, E. tenella, E. mitis, and E. praecox). When 0.2% berberine, a concentration that does not affect weight gain, was added to the diet, the 4 groups infected with E. acervulina, E. tenella, E. mitis, or E. praecox showed significant reductions in fecal oocyst shedding (P<0.05) compared to their respective infected and untreated controls. In chickens treated 0.5% berberine instead of 0.2% and infected with E. maxima, fecal oocyst production was significantly reduced, but body weight deceased, indicating that berberine treatment was not useful for E. maxima infection. Taken together, these results illustrate the applicability of berberine for prophylactic use to control most Eimeria infections except E. maxima. Further studies on the mechanisms underlying the differences in anticoccidial susceptibility to berberine, particularly E. maxima, are remained.