http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Impact of Periampullary Diverticulum on ERCP Performance: A matched Case-Control Study
Juan E. Corral,Omar Y. Mousa,Paul T. Kröner,Victoria Gomez,Frank J. Lukens 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.1
Background/Aims: Periampullary diverticulum (PAD) is frequently encountered during endoscopic retrograde cholangiopancreatography(ERCP) and has been associated with stone formation in the bile duct. The effects of PAD on the ERCP procedure have been oftendebated. We aimed to compare the therapeutic success of ERCP between patients with PAD and matched controls. Methods: We reviewed all ERCPs with findings of PAD in a national database (n=1,089) and compared them with age- and gendermatchedcontrols in a 1:3 fashion (n=3,267). Demographics, endoscopic findings, visualization of main structures, and therapeuticsuccess rates were compared between groups. Secondary analysis compared PAD cases and controls who had gallstone disease. Results: The average cohort age was 68.4±14.3 years and 55.1% were male. ERCP success was similar in both groups, and no significantinter-group differences were found in the multivariate analysis. The presence of PAD did not affect the rates of sphincterotomy orvisualization of main biliary structures. Secondary analysis showed similar success rates for gallstone removal between patients withPAD and controls. Conclusions: PAD may not be considered a hinderance to ERCP success. Further research is needed to determine the best approach tocannulate the ampulla and provide endoscopic therapy for different subtypes of PAD.
Do Han Kim,Somashekar G. Krishna,Emmanuel Coronel,Paul T. Kröner,Herbert C. Wolfsen,Michael B. Wallace,Juan E. Corral 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.2
Background/Aims: Endoscopic visualization of the microscopic anatomy can facilitate the real-time diagnosis of pancreatobiliarydisorders and provide guidance for treatment. This study aimed to review the technique, image classification, and diagnosticperformance of confocal laser endomicroscopy (CLE). Methods: We conducted a systematic review of CLE in pancreatic and biliary ducts of humans, and have provided a narrative of thetechnique, image classification, diagnostic performance, ongoing research, and limitations. Results: Probe-based CLE differentiates malignant from benign biliary strictures (sensitivity, ≥89%; specificity, ≥61%). NeedlebasedCLE differentiates mucinous from non-mucinous pancreatic cysts (sensitivity, 59%; specificity, ≥94%) and identifies dysplasia. Pancreatitis may develop in 2-7% of pancreatic cyst cases. Needle-based CLE has potential applications in adenocarcinoma,neuroendocrine tumors, and pancreatitis (chronic or autoimmune). Costs, catheter lifespan, endoscopist training, and interobservervariability are challenges for routine utilization. Conclusions: CLE reveals microscopic pancreatobiliary system anatomy with adequate specificity and sensitivity. Reducing costs andsimplifying image interpretation will promote utilization by advanced endoscopists.