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Zhixiang Huang,Chunyang Pan,Panling Huang,Jun Zhou,Xueen Li 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.4
During deep brain stimulation of the sub-thalamic nucleus (STN-DBS), frequently adjusting the position of the cannula may lead to changes in tissue viscoelasticity. To investigate the mechanical properties of tissue on implant path at repeated loads, three cyclic tension and relaxation tests were carried out at 10 % and 20 % strains. Results indicated that white matter was about 25 %-140 % stiffer than gray matter. Within 20 % strain, the natural viscoelasticity of tissue was not affected by the repeated tension. Whereas at 20 % strain, irreversible internal structure rearrangements occurred at the first relaxation due to the persistent strain action, and almost 60 % of the attenuation modulus generated in the initial 5 s of the process, which leads to a softer transformation of the tissue. Further simulated puncture experiments revealed that an irreversible depression occurred when the cerebral hemisphere was subjected to a constant pressure of cannula for 5 s.
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