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RISS 인기검색어
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- 저자 : Okayasu Ichiro (검색결과 4 건)
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Okayasu Ichiro,Mizuki Tachi,Sanuki Takuro,Kurata Shinji,Ayuse Takao 경희대학교 융합한의과학연구소 2021 Oriental Pharmacy and Experimental Medicine Vol.21 No.2
Goreisan might be a medicine to cure the pain caused by thirst and dry mouth symptom of glossodynia. All registered patients were treated with Goreisan by taking 7.5 g / day (min 3) for 2 weeks. Self-filled Visual Analogue Scale (VAS) and tongue perception test by nomo-filament. Furthermore, daily self-filled VAS evaluation was required patients’ home for two weeks during Goreisan administration. There was 57% of patients (8/14) showed “improved” after administration of 2 weeks Goreisan administration based on the criteria of 20% reduction of VAS compared to baseline. Self-filled VAS score was significant low (p = 0.006) at 2 weeks evaluation at second visit and remained lower level through 4 week observation periods compared to baseline value. QST significantly increased after 2 weeks administration of Goreisan (p = 0.008) and remained higher level through 4 week observation periods compared to baseline value. There was significant reduction of daily self-filled VAS patients’ home at day 3 and day 13 ~ day 14. (p < 0.05). There is a weak positive and negative correla-tion between Barometric pressure (hPa) and self-filled VAS scale (cm) in each patients. The administration of Goreisan for two weeks lead to significant reduction of pain perception based on the evaluation of Self-filled pain scale (VAS) and tongue perception test (QST). There is correlation between barometric pressure and self-filled VAS scale. This fact might indicate that Goreisan would be the alternative treatment for glossodynia patients. Goreisan would be a successful alternative treat-ment modality forglossodynia patients.Trial registration Current Controlled trials was registered with the UMIN Clinical TrialsRegistry (identifier: UMIN000035965, 02.21.2019).
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Okayasu, Ichiro,Komiyama, Osamu,Ayuse, Takao,De Laat, Antoon The Korean Dental Society of Anesthsiology 2018 Journal of Dental Anesthesia and Pain Medicine Vol.18 No.6
Background: Recently, we examined the effects of 2% lidocaine gel on the tactile sensory and pain thresholds of the face, tongue and hands of symptom-free individuals using quantitative sensory testing (QST); its effect was less on the skin of the face and hands than on the tongue. Consequently, instead of 2% lidocaine gel, we examined the effect of 8% lidocaine spray on the tactile sensory and pain thresholds of the skin of the face and hands of healthy volunteers. Methods: Using Semmes-Weinstein monofilaments, QST of the skin of the cheek and palm (thenar skin) was performed in 20 healthy volunteers. In each participant, two topical sprays were applied. On one side, 0.2 mL of 8% lidocaine pump spray was applied, and on the other side, 0.2 mL of saline pump spray was applied as control. In each participant, QST was performed before and 15 min after each application. Pain intensity was measured using a numeric rating scale (NRS). Results: Both the tactile detection threshold and filament-prick pain detection threshold of the cheek and thenar skin increased significantly after lidocaine application. A significant difference between the effect of lidocaine and saline applications was found on the filament-prick pain detection threshold only. NRS of the cheek skin and thenar skin decreased after application of lidocaine, and not after application of saline. Conclusion: The significant effect of applying an 8% lidocaine spray on the sensory and pain thresholds of the skin of the face and hands can be objectively scored using QST.
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Development of Monorail-type Mobile Robot for Field Environment and Plant Status Monitoring
( Takashi Okayasu ),( Daisaku Arita ),( Takashi Yoshinaga ),( Rin-ichiro Taniguchi Eiji Inoue ),( Yasumar Hirai ),( Muneshi Mitsuoka ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1
Field environmental and plant growth status monitoring is very important task to establish smart agriculture. Field monitoring device is usually installed only into the representative location in the field because of the management cost and complexity. Thus, their spatial distribution and time variation are not well grasped in actual cultivation. On the other hand, comprehensive analysis on the spatiotemporal field environmental and plant growth information is required in phenotyping researches. Various high-throughput plant phenotyping systems have been studied well and developed mainly in Europe and the US countries up to present. However, their systems are very expensive. Development of the low-price system is also required to create new cultivar and advanced agricultural production system. In this study, a monorail-type mobile robot for collecting field environment and plant status information was developed by using affordable devices such as a card-size microcomputer, sensors, and camera. Many of the robot frames were printed by 3D printer. The robot is driven by using two servo motors. The performance was verified by several conditions and then the spatiotemporal data measured was also evaluated.
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Sanuki, Takuro,Mishima, Gaku,Kurata, Shinji,Watanabe, Toshihiro,Kiriishi, Kensuke,Tachi, Mizuki,Ozaki, Yu,Okayasu, Ichiro,Kawai, Mari,Matsushita, Yuki,Miura, Keiichiro,Ayuse, Takao The Korean Dental Society of Anesthsiology 2015 Journal of Dental Anesthesia and Pain Medicine Vol.15 No.3
Background: We hypothesized that ketamine, when administered as the anesthetic induction agent, may prevent cardiovascular depression during high-dose remifentanil administration, unlike propofol. To test our hypothesis, we retrospectively compared the hemodynamic effects of ketamine, during high-dose remifentanil administration, with those of propofol. Methods: Thirty-eight patients who underwent oral surgery at the Nagasaki University Hospital between April 2014 and June 2015 were included in this study. Anesthesia was induced by the following procedure: First, high-dose remifentanil ($0.3-0.5{\mu}g/kg/min$) was administered 2-3 min before anesthesia induction;next, the anesthetic induction agent, either propofol (Group P) or ketamine (Group K), was administered. Mean arterial pressure (MAP) and the heart rate were recorded by the automated anesthesia recording system at four time points: immediately before the administration of high-dose remifentanil (T1);immediately before the administration of propofol or ketamine (T2);2.5 min (T3), and 5 min (T4) after the administration of the anesthetic induction agent. Results: In Group P, the MAP at T3 ($75.7{\pm}15.5mmHg$, P = 0.0015) and T4 ($68.3{\pm}12.5mmHg$, P < 0.001) were significantly lower than those at T1 ($94.0{\pm}12.4mmHg$). However, the MAP values in the K group were very similar (P = 0.133) at all time points. The heart rates in both Groups P (P = 0.254) and K (P = 0.859) remained unchanged over time. Conclusions: We showed that ketamine, when administered as the anesthetic induction agent during high-dose remifentanil administration, prevents cardiovascular depression.
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