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        Manuka Honey versus Antibiotic Ear Drops in Healing of Post-Operative Mastoid Cavity: A Prospective Randomized Trial

        Niveditha Damodharan,Roshan Kumar Verma,Archana Angrup,Naresh K Panda,Naresh K Panda 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.5

        Background and Objectives This study investigates the role of manuka honey in the healingof postoperative mastoid cavity. Subjects and Method This was a single centre prospective study on 40 consecutive patientsof chronic otitis media undergoing canal wall down mastoidectomy. Manuka honey soaked ingel foam was kept in the mastoid cavity for the study group and antibiotic soaked gel foam waskept for the control group. Culture swabs from mastoid granulations were sent at various timesfrom both groups. The healing of the mastoid cavity was assessed in the follow up period. Results Preoperatively 15 out of 20 patients (75%) had a positive aural swab culture in thestudy group while 11 out of 20 (55%) in the control group had a positive aural swab culture. Themost common organism isolated was Pseudomonas aeruginosa and Proteus mirabilis. Onemonth after mastoidectomy only 4 patients (20%) had sterile culture and 16 patients (80%) hadgrown organisms; in the control group, 7 patients (35%) had sterile culture and 13 patients (65%)had growth on culture. The mean merchant scores for the study group and the control were 2.61(2-5) and 2.05 (1-4), respectively. At 3 months 13 patients (65%) with sterile culture and 7 patients(35%) had growth on culture; in the control group, 16 patients (80%) had sterile cultureand 4 had shown persistent growth on culture (p=0.28). All positive cultures were aerobic inboth groups. The mean merchant scores for the study group and the control were 1.03 (0-4)and 0.7 (0-3), respectively (p=0.09). Conclusion Healing of mastoid cavity was almost similar in both groups (p>0.05). Manukahoney exhibited antibacterial activity against Pseudomonas, Proteus, Klebsiella, Escherichiacoli, Staphylococcus

      • Use of Computational Fluid Dynamics for the Design and Analysis of Gas Turbine Combustors

        Niveditha Krishnamoorthy,Piyush Thakre,Yongzhe Zhang,Richard Clayton,Graham Goldin,Rajesh Rawat 한국추진공학회 2015 한국추진공학회 학술대회논문집 Vol.2015 No.11

        The use of computational fluid dynamics (CFD) for the design and analysis of the flow and combustion in gas turbine combustors is considered to be a cost effective alternative to time-consuming and expensive design of experiments studies. With stringent emission regulations being enforced for these combustion systems, efforts towards optimization of the combustor geometry, and its operating conditions to minimize fuel consumption, emissions, and cost are also being undertaken using CFD. Reacting flow modeling in gas turbine combustors is a multi-scale, multi-physics process which requires an adequate representation of the flow, chemistry, and heat transfer mechanisms taking place in these systems. The models/approximations used in simulating gas turbine combustors directly influence the predictive capability of the simulations. In this study, the commercial software STAR-CCM+ is used model all the processes taking place in a gas turbine combustor. STAR-CCM+ solves the Navier-Stokes equation using the finite volume formulation. The choice to represent the combustion chemistry via global reactions, tabulated methodology, or detailed kinetic modeling is available for premixed, non-premixed and partially premixed combustion regimes. The combustion model selection is typically driven by the intended purpose of the simulation. Radiative heat transfer is modeled using the discrete ordinates methodology. In order to study the mechanical durability of various components in these systems, a full conjugate heat transfer (CHT) analysis is also performed where, the liner and other solids are explicitly modeled in the fully-coupled simulation. In this investigation, both the Reynolds Averaged Simulation (RANS) methodology and the Large-Eddy Simulation (LES) methodology are explored and the results are summarized.

      • Praseodymium doped ceria as electrolyte material for IT-SOFC applications

        Shajahan, Irfana,Ahn, Junsung,Nair, Parvathi,Medisetti, Srikar,Patil, Sunaina,Niveditha, V.,Uday Bhaskar Babu, G.,Dasari, Hari Prasad,Lee, Jong-Ho Elsevier 2018 Materials chemistry and physics Vol.216 No.-

        <P><B>Abstract</B></P> <P>Praseodymium-doped ceria (PDC, Ce<SUB>0.9</SUB>Pr<SUB>0.1</SUB>O<SUB>2</SUB>) electrolyte material for intermediate temperature solid oxide fuel cells (IT-SOFCs) has been successfully synthesised by EDTA-citrate method. From X-Ray diffraction (XRD), fluorite structure along with a crystallite size of 5.4 nm is obtained for PDC nanopowder calcined at 350 °C/24 h. Raman spectroscopy confirmed the structure, presence of oxygen vacancies with the manifestation of the main peak at 457 cm<SUP>−1</SUP> and with a secondary peak at 550 cm<SUP>−1</SUP>. From Transmission Electron Microscopy (TEM) analysis, the average particle size is around 7–10 nm and selected area electron diffraction (SAED) patterns further confirmed the fluorite structure of PDC nanopowder. The PDC nanopowder displayed a BET surface area of 65 m<SUP>2</SUP>/g with a primary particle size of ∼13 nm (calculated from BET surface area). Dilatometer studies revealed a multi-step shrinkage behaviour with the multiple peaks at 522, 1171 and 1461 °C which may be originated due to the presence of multiple size hard agglomerates. The PDC electrolyte pellet sintered at 1500 °C displayed an ionic conductivity of 1.213E-03 S cm<SUP>−1</SUP> along with an activation energy of 1.28eV. Instead of a single fluorite structure, XRD of sintered PDC pellet showed multiple structures (Fluorite structure (CeO<SUB>2</SUB>) and cubic structure (PrO<SUB>2</SUB>).</P> <P><B>Highlights</B></P> <P> <UL> <LI> Praseodymium doped ceria (PDC) electrolyte was synthesised by EDTA citrate method. </LI> <LI> Dilatometer study revealed multiple shrinkage behaviour of PDC. </LI> <LI> PDC showed an ionic conductivity of 1.213E-03 S cm<SUP>−1</SUP> at 700 °C. </LI> <LI> XRD at 1500 °C revealed that they crystallize as fluorite CeO<SUB>2</SUB> + cubic PrO<SUB>2</SUB> phase. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

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