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      • KCI등재

        Reference range of random urinary calcium creatinine ratio in North Indian children and adolescents

        Raman Kumar Marwaha,Mahendra Kumar Garg,Navin Dang,Ambrish Mithal,Aditi Chadha,Nandita Gupta,Manchanda Raj Kumar 대한소아내분비학회 2019 Annals of Pediatirc Endocrinology & Metabolism Vol.24 No.1

        Purpose: Urinary calcium creatinine ratio (UCaCrR) is a reliable indicator for monitoring hypercalciuria following vitamin D supplementation. However, the reference range varies from region to region. Previous studies did not take vitamin D and parathyroid hormone status into account while evaluating UCaCrR. Hence, we undertook this study to establish the 95th percentile of UCaCrR as an indicator of hypercalciuria in North Indian children and adolescents. Methods: Four hundred seventy-three participants (boys 62.2%, girls 37.8%) with adequate dietary calcium intake, normal serum levels of 25-hydroxy-vitamin D (>20 ng/mL), and without secondary hyperparathyroidism following supplementation were selected for evaluation of UCaCrR. Results: The mean age and body mass index of subjects were 11.2±2.6 years and 18.0±3.6 kg/m 2 , respectively. The 95th percentile of UCaCrR in the study population was 0.126. The mean, median, and 95th percentile of UCaCrR was significantly higher in prepubertal children (age ≤10 years) (0.0586±0.0374, median=0.0548, 95th percentile=0.136) compared to those >10 years old (0.0503±0.0363, median=0.0407, 95th percentile=0.123, P=0.02). No significant difference in UCaCrR was observed between genders and different weight categories. Conclusion: UCaCrR of 0.13 defines the cutoff value for hypercalciuria in North Indian children and adolescents with adequate dietary intake of calcium and sufficient serum vitamin D levels.

      • SCOPUSKCI등재

        Design and Performances of Implantable CPW Fed Apollian Shaped Antenna at 2.45 GHz ISM Band for Biomedical Applications

        Kumar, S. Ashok,Sankar, J. Navin,Dileepan, D.,Shanmuganantham, T. The Korean Institute of Electrical and Electronic 2015 Transactions on Electrical and Electronic Material Vol.16 No.5

        A novel implantable CPW fed Apollian shaped antenna embedded into human tissue is proposed for ISM band biomedical applications. The proposed antenna is made compatible for implantation by embedding it in an alumina ceramic substrate(ε<sub>r</sub>=9.8 and thickness= 0.65 mm). The proposed antenna covers the ISM band of 2.45 GHz. The radiation parameters such as return loss, xy-plane, xz-plane, and yz-plane etc., are measured and analyzed using the agilent vector network analyzer. The proposed antenna has substantial advantages, including low profile, miniaturization ability, lower return loss, better impedance matching, and high gain over conventional implanted antennas.

      • KCI등재

        Is long term storage of cryopreserved stem cells for hematopoieticstem cell transplantation a worthwhile exercise in developingcountries?

        Santhosh Kumar Devadas,Minal Khairnar,Sumathi S Hiregoudar,Shashank Ojha,Sachin Punatar,Alok gupta,Anant Gokarn,Pallavi Bhole,Sadhana Kannan,Navin Khattry 대한혈액학회 2017 Blood Research Vol.52 No.4

        Background: Stem cell units (SCUs) that are cryopreserved prior to both autologous and allogeneic hematopoietic stem cell transplants (for donor lymphocyte infusion) remain unused or partially used several times, and become an increased burden to blood banks/SCU repositories. Because of the scarcity of data regarding the duration for which the storage is useful, there is no general consensus regarding disposal of SCUs. Methods: We conducted a retrospective audit of SCU utilization in 435 patients who planned to undergo either autologous stem cell transplantation (auto-SCT) (N=239) or allogeneic stem cell transplantation (allo-SCT) (N=196) at a tertiary cancer care center between November 2007 to January 2015. Results: Our cohort consisted of 1,728 SCUs stored for conducting auto-SCT and 729 SCUs stored for conducting donor lymphocyte infusions (DLIs) after allo-SCT. Stem cells were not in-fused in 12.5% of patients who had planned to undergo auto-SCT, and 80% of patients who underwent allo-SCT never received DLI. Forty-one percent of SCUs intended for use in auto-SCT remained unutilized, with a second auto-SCT being performed only in 4 patients. Ninety-four percent of SCUs intended for carrying out DLIs remained unused, with only minimal usage observed one year after undergoing allo-SCT. Conclusion: The duration of storage of unused SCUs needs to be debated upon, so that a consensus can be reached regarding the ethical disposal of SCU.

      • KCI등재

        Is long term storage of cryopreserved stem cells for hematopoieticstem cell transplantation a worthwhile exercise in developingcountries?

        Santhosh Kumar Devadas,Minal Khairnar,Sumathi S Hiregoudar,Shashank Ojha,Sachin Punatar,Alok gupta,Anant Gokarn,Pallavi Bhole,Sadhana Kannan,Navin Khattry 대한혈액학회 2017 Blood Research Vol.51 No.4

        Background: Stem cell units (SCUs) that are cryopreserved prior to both autologous and allogeneic hematopoietic stem cell transplants (for donor lymphocyte infusion) remain unused or partially used several times, and become an increased burden to blood banks/SCU repositories. Because of the scarcity of data regarding the duration for which the storage is useful, there is no general consensus regarding disposal of SCUs. Methods: We conducted a retrospective audit of SCU utilization in 435 patients who planned to undergo either autologous stem cell transplantation (auto-SCT) (N=239) or allogeneic stem cell transplantation (allo-SCT) (N=196) at a tertiary cancer care center between November 2007 to January 2015. Results: Our cohort consisted of 1,728 SCUs stored for conducting auto-SCT and 729 SCUs stored for conducting donor lymphocyte infusions (DLIs) after allo-SCT. Stem cells were not in-fused in 12.5% of patients who had planned to undergo auto-SCT, and 80% of patients who underwent allo-SCT never received DLI. Forty-one percent of SCUs intended for use in auto-SCT remained unutilized, with a second auto-SCT being performed only in 4 patients. Ninety-four percent of SCUs intended for carrying out DLIs remained unused, with only minimal usage observed one year after undergoing allo-SCT. Conclusion: The duration of storage of unused SCUs needs to be debated upon, so that a consensus can be reached regarding the ethical disposal of SCU.

      • A Study on Perceived Service Quality in the Indian Rural and Urban Hospitals

        Naeema Mohammed,Navin Kumar ASCONS 2018 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.2 No.1

        Hospital service quality is the variation between the patient’s perceptions about the services delivered by a healthcare organization and their expectations about healthcare organizations delivering such services. Patient perspective is the ultimate indicator of healthcare service quality as it enables them to judge the performance of the services provided by the hospital. A huge gap exists between the quality of the healthcare services provided by the hospitals in rural and urban areas. The quantitative study was conducted to understand the perceptional differences in the service quality between the urban and rural hospitals. It was a survey that documented the patient perspective of hospital service quality by measuring various dimensions like healthcare delivery, facilities, financial access to care, diagnostic aspects of care, health personnel conduct and drug availability. The sample consisted of 115 residents, chosen based on convenience, from urban and rural areas. The responses were analyzed using SPSS 20 software. From the findings, it was inferred that there are perceptional differences in the service quality between rural and urban hospitals. Further, perceptional differences exist in the facilities provided between the rural and urban hospitals. Financial and physical access to care widely differ between rural and urban hospitals. Overall, the perception of service quality is higher in the urban hospitals than in the rural hospitals. Thus, study provides insights to the hospital administrators and the managers in enhancing the quality of services, based on the perceptions and needs of the patients.

      • A Study on Patient Satisfaction : Differences in Private and Public Hospitals.

        Nimitha Kateel,Navin Kumar Koodamara ASCONS 2018 INTERNATIONAL JOURNAL OF EMERGING MULTIDISCIPLINAR Vol.2 No.1

        Over the years the quality of care provided by healthcare organizations is measured through an important tool called patient satisfaction. It is important to understand the perceptions of patients on health care services in order to understand the expectations levels and thus the quality of services can be improved. Also such perception levels may differ across private and public hospitals. This study aims to understand such perceptual differences in the patient satisfaction level of private and public hospitals and also understand the various factors that influences patient satisfaction in a hospital. The study was conducted on 136 respondents who have visited a hospital earlier either private or public. Self-administered questionnaires were provided to the respondents and they were assessed on various factors such as front office services, doctor consultation, diagnostic services, hospital facilities etc. The study revealed that there was a significant relationship between doctor consultation, hospital facilities and patient satisfaction. Further it was also understood that the satisfaction levels were better in private hospitals when compared to public hospitals. Such findings of various factors influencing patient satisfaction help the managers in create policies that address patient’s perceptions. Thus help in improving the quality of services provided.

      • KCI등재

        Combined rotor fault diagnosis in rotating machinery using empirical mode decomposition

        Sukhjeet Singh,Navin Kumar 대한기계학회 2014 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.28 No.12

        Unbalance, misalignment, partial rub, looseness and bent rotor are one of the most commonly observed faults in rotating machines. These faults cause breakdowns in rotating machinery and create undesired vibrations while operating. In this study, an approach to detectcombined fault of unbalance and bent rotors for advance detection of the features of the fault rotors diagnosis is proposed. Empiricalmode decomposition (EMD) is used efficiently to decompose the complex vibration signals of rotating machinery into a known numberof intrinsic mode functions so that the fault characteristics of the unbalanced and bowed shaft can be examined in the time-frequencyHilbert spectrum. A test bench of Spectra-Quest has been used for performing experiments to illustrate the unbalance and the bent rotorconditions as well as the healthy rotor condition. Analysis of the results shows the usefulness of proposed approach in diagnosing theunbalance and bowed fault of the shaft in rotating machinery.

      • KCI등재

        Optimization of Media Components for Enhanced Arachidonic Acid Production by Mortierella alpina under Submerged Cultivation

        Alpettiyil Nisha,Navin Kumar Rastogi,Govindarjulu Venkateswaran 한국생물공학회 2011 Biotechnology and Bioprocess Engineering Vol.16 No.2

        Mortierella alpina, an oleaginous zygomycete is a potent producer of arachidonic acid, the pharmaceutically and nutraceutically important polyunsaturated fatty acid of the n-6 series. It serves a wide variety of purposes,from being a purely structural element in phospholipids to being involved in signal transduction, and as a substrate for a host of derivatives involved in second messenger function. Arachidonic acid has applications in diverse areas including infant and geriatric nutrition. In the present study,the interactive effects of four major media constituents on arachidonic acid production were investigated by applying a central composite rotatable design (CCRD) and response surface methodology (RSM). The independent variables,which were selected byconcentrations of glucose, corn solids, KH_2PO_4, and KNO_3 influenced the production of biomass, total lipid, and arachidonic acid by M. alpina. A second-order polynomial was fitted by multiple regression analysis of the experimental data. The optimum conditions (glucose 10.0 g/L, corn solids 5.0 g/L, KH_2PO_4 1.0 g/L,and KNO_3 1.0 g/L) resulted in maximum production of arachidonic acid (1.39 g/L) and the corresponding biomass and total lipid concentrations were 12.49 and 5.87 g/L,respectively.

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