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Himanshi Mehta,Megha Gupta,Parminder Kaur,Jaspreet Kaur,Naveen Kaushal 한국진공학회(ASCT) 2021 Applied Science and Convergence Technology Vol.30 No.3
Biomolecules mediated synthesis of nanoparticles (NPs) has revolutionized the nanotechnology research field due to its eco-friendly and non-toxic nature. The green approaches of NPs synthesis using plant extracts offer an effective and better alternative than other synthesis methods. Metal-based NPs have emerged at the forefront of biomedicine due to their versatility in health and therapeutics. In this context, Selenium (Se), a versatile trace element is known for its critical role in various pathophysiological processes through regulation of cellular redox status and inflammatory pathways besides others. However, these beneficial effects of Se are limited by its narrow physiologically relevant concentration range. Deficiency or excess of Se is associated with numerous pathologies and toxicities. Thus, in current study we have synthesized and characterized Hempseed (Cannabis sativa) based novel biogenic Se nanoparticles (SeNPs) using UV visible spectroscopy, DLS, EDX, FE-SEM, and FT-IR. Further, the phytochemical profiles and antioxidant as well as anti-inflammatory potential of these SeNPs were evaluated to ascertain their physiological benefits. Results indicated the spherical shaped SeNPs of average size 140–150 nm with favourable zeta potential of −45.0 mV. The phytochemical and Se analysis validated the redox modulatory anti-inflammatory potential of these hempseed based green SeNPs.