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      • SCOPUSKCI등재

        On a Class of Analytic Functions Defined by Fractional Derivative, II

        Nalini Shukla KYUNGPOOK UNIVERSITY 1998 Kyungpook mathematical journal Vol.38 No.1

        Let H^(λ)_(p)(A,B) denote the class of functions◁수식삽입▷(원문을 참조하세요) which are analytic in the unit disc U = {z : |z| < 1} and satisfy the condition ◁수식삽입▷(원문을 참조하세요) where -1≤ A < B ≤1, 0 <λ≤ 1 and ­ ◁수식삽입▷(원문을 참조하세요) Here D^(λ)_(z)f(z) is the fractional derivative operator of orderλ. In this paper, we investigate certain properties of the above mentioned class.

      • KCI등재

        An Evidence for Host Translation Inhibitory Factor Encoded in a Polydnavirus, Cotesia glomerata Bracovirus, Genome and Its Expression in Parasitized Cabbage White Butterfly, Pieris rapae

        Nalini Madanagopal,김용균 한국응용곤충학회 2007 Journal of Asia-Pacific Entomology Vol.10 No.4

        Polydnavirus is a DNA virus symbiotic to some endoparasitic wasps and plays a critical role in accomplishing successful parasitic life cycle of host wasps. Host translation inhibitory factor (HTIF) has been found in some polydnaviral genomes and performs parasitic functions leading to host immunosuppression and redirecting host nutrient usage to wasp development. The cabbage white butterfly, Pieris rapae, parasitized by a gregarious endoparasitoid, Cotesia glomerata, undergoes several physiological alterations including immune malfunctioning and failure of pupal metamorphosis. C. glomerata possesses its own symbiotic polydnavirus, C. glomerata bracovirus (CgBV). Its genome consisted of at least 12 segments in unequal amounts. Parasitized P. rapae hemolymph contained HTIF-like protein, which was determined through an immunoblotting assay using HTIF antibody of C. plutellae bracovirus (CpBV). RT-PCR using HTIF primers of CpBV produced an HTIF-like gene in P. rapae larvae parasitized by C. glomerata. Also, this HTIF-like gene was encoded in CgBV genome and its partial sequence of CgBV showed highly homology (98.5%) to amino acid sequence of an HTIF of CpBV, called CpBV15α. These results suggest that a common HTIF- like moiety may be shared among Cotesia-associated bracovirus.

      • KCI등재

        Parasitism by Cotesia glomerata Induces Immunosuppression of Pieris rapae: Effects of Ovarian Protein and Polydnavirus

        Nalini Madanagopal,Yonggyun Kim 한국응용곤충학회 2006 Journal of Asia-Pacific Entomology Vol.9 No.4

        A gregarious endoparasitoid wasp, Cotesia glomerata, parasitizes the cabbage butterfly, Pieris rapae. During wandering larval stage for pupal metamorphosis, the parasitoid larvae egress from the parasitized host to form cocoons thus eventually leading to death of the host. This study focused on the effect of C. glomerata parasitization on cellular immune response of P. rapae. For this purpose, an ideal anticoagulant buffer was formulated to procure the hemocytes in native form with morphological, behavioral, and functional characteristics. The hemocytes selectively encapsulated only DEAE beads under in vitro conditions and a quantitative study revealed about 70% of the beads being encapsulated. On the other hand, calyx fluid from C. glomerata injected to P. rapae markedly inhibited the spreading ability of the hemocytes in a dose-dependent manner and also attenuated the in vitro encapsulation response of the hemocytes against the cationic bead. The calyx fluid contained polydnavirus as well as ovarian proteins. The isolated polydnavirus genome consisted of variously sized-segments with their unequal amounts. The P. rapae injected with the calyx fluid expressed several polydnaviral genes within 2 h. These results suggest that the immunosuppression of the parasitized P. rapae may be induced by the polydnaviral gene products as well as ovarian proteins.

      • KCI등재

        Biochemical Characterization of C-type Lectin in the Diamondback Moth, Plutella xylostella (Yponomeutidae: Lepidoptera)

        Nalini Madanagopal,김용균 한국응용곤충학회 2007 Journal of Asia-Pacific Entomology Vol.10 No.3

        Lectins due to their affinity to carbohydrate moiety are involved in diverse functions like cell attachment in embryogenesis, organogenesis and cellular trafficking as well as nonself recognition in immune responses. Agglutinating activity was detectable in Plutella xylostella (Yponomeutidae: Lepidoptera) against 14 different species including bacterial and yeast cells, among which the whole body homogenate of P. xylostella agglutinated Providencia vermicola, Flavobacterium sp., and Saccharomyces cerevisiae with high titers. On analysis of physico-chemical properties, this putative agglutinating factor (s) was specifically dependent on the presence of Ca++ for its activity and was reversibly sensitive to EDTA. The agglutinating activity was stable at pH 6-8, but was heat-labile. The agglutinating factor (s) was proteinaceous in nature as it was completely precipitable by ammonium sulphate. Its carbohydrate binding activity was demonstrated by inhibition assay, which revealed that methyl α-D-mannopyranoside inhibited agglutination against P. vermicola. In contrast, P. xylostella parasitized by an endoparasitoid wasp, Cotesia plutellae (Braconidae: Hymenoptera), also showed the agglutination properties with somewhat higher activity than the nonparasitized. Carbohydrate inhibition assay with methyl α-D-mannopyranoside was detectable at one-fold higher concentration in the homogenate of the parasitized larvae, suggesting that the agglutinating factor (s) is inducible or due to de novo parasitism-specific synthesis. These results suggest the presence of calcium-dependent lectin in P. xylostella and an alteration in the agglutinating property by C. plutellae parasitization.

      • KCI등재

        Primary multifocal cystic signet ring neuroendocrine tumor of liver: a case report

        ( Nalini Bansal ),( Brahmananda Satapathy ) 대한간암학회 2021 대한간암학회지 Vol.21 No.2

        Primary signet ring neuroendocrine tumors of the liver are extremely rare tumors. Morphologically, they mimic signet ring cell adenocarcinomas; however, the absence of mucin by special stains and the expression of neuroendocrine markers help to diagnose these tumors. We herein report a case of a 47-year-old female who presented with multiple solid and cystic lesions in both liver lobes, which were initially suggested to be biliary cystadenocarcinoma on imaging. Liver biopsy of the lesion revealed the presence of a signet ring neoplasm with diffuse expression of synaptophysin and pan-cytokeratin. The case was subsequently diagnosed as a primary hepatic signet ring neuroendocrine tumor. The patient was offered 3 cycles of chemotherapy and is well preserved after 14 months of diagnosis. Although this is an extremely rare entity, its possibility should be considered in the differential diagnosis of neoplasms characterized by signet ring cell morphology. (J Liver Cancer 2021;21:187-193)

      • KCI등재

        Effect of Multiparity and Prolonged Lactation on Bone Mineral Density

        ( Nalini Sharma ),( Tanie Natung ),( Rituparna Barooah ),( Santa Singh Ahanthem ) 대한폐경학회 2016 대한폐경학회지 Vol.22 No.3

        Objectives: This study was done to determine the effect of multiparity and prolonged lactation on bone mineral density (BMD). Methods: This cross-sectional study included 196 perimenopausal and postmenopausal women aged 40 to 60 years old. Age, body mass index (BMI), menopausal status, duration of menopause, parity and total duration of lactation, nutritional history were recorded. Lumbar spine (LS; L2-L4) and femur neck (FN) BMD were measured using dual energy X-ray absorptiometry. Correlation of parity and lactation with BMD were investigated using multiple regression analysis. Results: Parity was inversely correlated to BMD for LS (β = -0.266, P = 0.001) and FN (β = -0.380, P = 0.000). This relation remained significant even after adjusting for age, BMI and duration of menopause. Duration of lactation was inversely correlated with BMD for LS (β = -0.271, P = 0.001) but no for FN (β = -0.124, P = 0.130). Conclusions: Multiparity and prolonged lactation have negative impact on BMD especially with in a socioeconomic group whose nutritional intake is borderline. Our data support that parity and duration of lactation can be associated with future osteoporosis. (J Menopausal Med 2016;22:161-166)

      • KCI등재

        Interrogation of earthworm (Clitellata: Haplotaxida) taxonomy and the DNA sequence database

        Nalini Tiwari,Azhar Rashid Lone,Samrendra Singh Thakur,Shweta Yadav 국립중앙과학관 2021 Journal of Asia-Pacific Biodiversity Vol.14 No.1

        The DNA sequence database assists us with great potential in species identification because it is practicaland affordable to perform. More often, the identification using molecular data helps to identifymorphologically variable individuals of same species, including juvenile specimens. In case of earthworms,the classical standards of taxonomy are mainly based on genital structures, while the collectionof the sexually agile worm is difficult. Hence, typical barcode marker cytochrome c oxidase subunit 1 wasused to explore species richness of the study area. From taxonomic relationship, the valid identificationof voucher specimens was taken into consideration for characterization. The species richness of earthwormsp. viz., Metaphire houlleti, Perionyx sp., Drawida minuta, Eudichogaster prashadi, Lennogasterpusillus, Octochaetona beatrix, and Octochaetona prashadi were recorded and analyzed. Less than 1%divergence within species was found, whereas divergence between species was greater than 15% in allcases. The phylogenetic tree(s) was constructed using the best-fitted substitution model of evolution andspecies delimitation by Automatic Barcode Gap Discovery, operational taxonomic units, and networkanalysis. The prospective and limitations of molecular taxonomy and the vital role of publicly availablenucleotide sequence databases were reviewed to inventor earthworm diversity. The study shows theuniversality of single locus persists utopian and the use of other typical loci may strengthen earthwormdiversity assessment.

      • KCI등재

        Metachronous Cancer of Breast and Adenocarcinoma of Cervix: A Rare Case Report

        ( Nalini Sharma ),( J Lalnunnem Thiek ),( Das Rituparna ),( Jaya Mishra ),( Ahanthem Santa Singh ) 대한폐경학회 2017 대한폐경학회지 Vol.23 No.2

        The occurrence of a second primary cancer in a cancer survivor is well documented. It may be synchronous or metachronous. Incidence of metachronous cancer involving cervix is 0.82% to 1.33%. One such metachronous cancer is that of breast and cervix. We present a case of a woman who received tamoxifen for invasive ductal cancer of breast following a modified radical mastectomy and subsequently developed adenocarcinoma of cervix after six month of tamoxifen therapy. The role of tamoxifen in pathogenesis of cervical cancer and that of human papillomavirus infection in pathogenesis of both cancer of cervix and breast cancer has been well recognized. In our patient, the adenocarcinoma of cervix (rare occurrence) which is likely due to six month of tamoxifen therapy is a perplexing question. Women diagnosed and treated for breast cancer need to be followed up for development of other metachronous gynecological cancers. (J Menopausal Med 2017;23:131-134)

      • KCI등재

        Case Report : Spontaneous Perforation of Pyometra

        ( Nalini Sharma ),( Ahanthem Santa Singh ),( Wankhar Bhaphiralyne ) 대한폐경학회 2016 대한폐경학회지 Vol.22 No.1

        Pyometra is collection of purulent material which occurs when there is interference with its normal drainage. It is an uncommon condition with incidence of 0.1 to 0.5% of all gynecological patients. Spontaneous rupture of uterus is an extremely rare complication of pyometra. A 65-year-old lady presented with pain abdomen and purulent vaginal discharge. Preoperative diagnosis of pyometra was made by magnetic resonance imaging (MRI). Laparotomy followed by peritoneal lavage and repair of perforation was performed. Although spontaneously perforated pyometra is rare, the condition must be borne in mind with regard to elderly women with acute abdominal pain. Preoperative diagnosis of perforated pyometra is absolutely essential. Computed tomography (CT) and MRI are diagnostic tools. In selected cases conservative approach at surgery can be opted. (J Menopausal Med 2016;22:47-49)

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