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생쥐의 骨髓細胞에 대한 Aminopterin 과 Amethopterin의 細胞遺傳學的 影響
양재섭,강봉석,최명철,김길웅 대구대학교 기초과학연구소 1987 基礎科學硏究 Vol.4 No.-
Aminopterin and amethopterin(Methotrexate; MTX) are antifolic drugs and anti-tumour agents, which inhibit DNA biosynthesis, were previously known to have mutagenic effects on various mammalian cells. Mutagenecity and toxicity of these agents have been determined by various methods. In the present study, effects of two anti-tumour agents on cultured mouse bone marrow cells were analyzed by observing chromosome aberrations and mitotic index. The results of the present investigation were as follows; 1. The chromosome aberrations analyzed were mainly chromosome gaps and breaks, chromatid gaps and breaks. In the Group-1 (treated for 8 hours), chromosome aberrations were not shown and it seems that mutagenic actions of anti-tumour agents were not aroused due to the short period of culture and the other culture conditions. However, in the Group-2 (treated for 24 hours), as the concentrations of antifolic compounds were increased, chromosome aberrations were increased. 2. In mitotic index, the Group-I treated with aminopterin and amethopterin showed marked inhibition in the mitotic index(O. 6% in aminopterin, 0.9% in amethopterin) at the high concentrations, compared with that of control (5. 2%). Both aminopterin and amethopterin showed a dose-dependent reduction of mitotic index. In the Group-2, each group treated with two antifolic compounds showed no marked differences in the mitotic index. compared with that of control. 3. Aminopterin was a more potent agent for induction of chromosome aberration than amethopterin.
3-Joint Planar Type 로봇 매니퓰레이터의 자기동조적응제어에 관한 연구
김규로,양희주,유용석,최명진,오택열 慶熙大學校 大學院 院友會 1996 高凰論集 Vol.17 No.-
This study has parallelogram trajectory tracking of Three Joint Planar type Robot Manipulator. The equation of motion for the three joint planar manipulator are obtained by substituting Lagrange's energy expression into Euler-Lagrange's equation and forming the appropriate derivative. Lagrangian method allows us to obtain the dynamics equations for very complicated systems in the simplest manner possible. SISO model is used for design of the controller. The design of controllers may be considered primary controller for manipulators to track the desired trajectory under ideal conditions and secondary controller to compensates for undesirable deviations of the motion from the trajectory caused by external and internal disturbances. The aim of this paper is to evaluate the efficiency by self-tunning adaptive control and considering a characteristic of control. Through the computer simulation, obtained the following results 1) selt-tunning adaptive control is superior to PD control, 2) During the learning period, the adaptive control algorithm is searching proper estimates and controller gains. After this period, the outputs of the joints start tracking closely the desired valued.
이희자,조양석,조광명 한국환경과학회 2000 한국환경과학회지 Vol.9 No.1
Every year, 1.1 million tons of rice-hull are produced in South Korea by the by-product in pounding rice. But they has mainly been utilized as a fuel, agricultural compost and moisture proofs. So, it's very valuable to use waste rice-hull for activated carbon manufacture. SiO_2 content was the highest among inorganics in rice-hull. Therefore, the SiO_2 extraction experiments were carried out under the various conditions of pH 9 to 14, reaction time from 2 to 24 hrs and various temperature of 20 to 100℃. The results showed that increase in pH and temperature enhanced SiO_2 extraction from the carbonized rice-hull. The surface area of the carbonized rice-hull indicating activated carbon adsorption capacity was very small as 178∼191 ㎡/g at first. However, it was increased to 610∼675 ㎡/g when extracted in alkali solution at 100℃. When the mixing rate of carbonized rice-hull and NaOH was 1:1.5, iodine No. and surface area of activated rice-hull during 10 min at 700℃ were 1,650 ㎎/g and 1837 ㎡/g, respectively. Subsequently, an activated carbon with specific surface area of 1,300∼1,900㎡/g was manufactured in a short contact time of 10∼30 min with a mixing rate of 1:1.5 in carbonized rice-hull and NaOH, and iodine No. and specific surface area increased as the amount of SiO_2 removal increased.
김영오,서태석,양수경,류명주,고대식 牧園大學校 建築·都市硏究센터 1998 建築·都市環境硏究 Vol.6 No.-
본 연구에서는 국내 건축물의 통신실에 대한 운영상의 문제점을 조사·분석하고 효율적인 구내통신 서비스를 위한 통신실의 설계 및 설치기준안을 제시하였다. 국내 업무용 건물의 통신실 설계 및 설치현황을 조사한 결과, 대부분의 통신실 크기가 장비의 설치 및 유지보수시에 필요한 여유공간의 고려가 없이 작게 설치되어 있었으며, 위치 고려의 문제점도 발견되는 등 통신실의 설계 및 설치단계에서 통신실의 중요성이 크게 인식되지 못한 문제점이 있었다. 한편, 통신실에 관한 국내·외 기준을 비교한 결과, 대부분의 선진국에서는 통신실의 설치기준이 자세하게 포함된 구내통신설비의 설계 및 설치 기술표준을 제정, 운용하고 있었지만, 국내에는 통신실에 대한 구체적인 설계 및 설치 표준이 없는 실정이다. 따라서, 본 연구에서는 국내 주거용 및 업무용 구내통신설비 설치표준과 미국의 통신협회인 BICSI 매뉴얼을 기반으로 하고 국내상황을 고려한 통신실의 설계 및 설치 기준안을 작성하였다.
이재익,박정하,김준영,조영완,진한영,강명주,정은욱,박석주,양성연 인제대학교 2006 仁濟醫學 Vol.27 No.-
Anisakiasis refers to parasitic infestation by nematode larvae that belongs to the subfamily Anisakinae, and this condition is seen in people who eat inadequately prepared or raw salt-water fish. While gastric anisakiasis is commonly diagnosed by endoscopic technique, intestinal anisakiasis is rare because it is less common and the clinical and radiologic features are poorly understood. The authors report a case of human anisakiasis involving the ileocecal valve in 62-year-old man who had the history of eating raw cuttlefish.
Myung-Seok Yang,Nam-Kyu Kang,Tae-Hyun Kim,Won-Kyun Joo,Min-Woo Park,Kwang-Nam Choi 한국정보통신학회 2014 2016 INTERNATIONAL CONFERENCE Vol.6 No.1
National Science and Technology Information Service (NTIS) builds a database of federal R&D information (project information, human resources, accomplishments, equipment list, and etc.) by cooperating with 17 different ministries of the government, and provides various services using the database. This paper proposes a method to build a knowledge map that draws a network of collaborative researchers that participate in federal R&D programs. The map contains information on relations between cooperative researchers, information on key researchers with vast experience of research, and the distribution of the research funding.
Improvement for Generation Process of Researchers Map on National R&D data
Myung-Seok Yang,Nam-Kyu Kang,Tae-Hyun Kim,Won-Kyun Joo,Kwang-Nam Choi 한국정보통신학회 2015 2016 INTERNATIONAL CONFERENCE Vol.7 No.1
NTIS has provided on a trial basis Researchers Map Service with respect to the 25th specific subject areas in the form of knowledge map including information such as Research groups, Clusters and Top-20 Researchers analyzing information of researchers participating on the national R&D projects. Researchers Map is significant in that it provides to analyze the information of the researchers participating in National R&D Program. but at the point of user view, there is a need to improve in that it is limited to providing only for specific subject areas. In this paper, we establish the improvement analyzing the generation process of the Researchers Map. we propose a service model that can be generated a Researchers Map by users, the generation process of researchers map that users can directly extract the R&D data in specific subject area, analyze data and create Researcher Map.
An Analysis of National R&D Collaborators Network based on the NTIS Data
Myung-Seok Yang,Nam-Kyu Kang,Tae-Hyun Kim,Won-Kyun Joo,Min-Woo Park,Kwang-Nam Choi 보안공학연구지원센터 2014 International Journal of Software Engineering and Vol.8 No.11
Many researchers jointly participate in various research topics of national R&D programs, and they achieve accomplishments such as journal papers and patents as the outcome of these programs. The government administration and research administering institutes also do their part in the advancement of national science and technology by strategically distributing R&D programs to researchers, reviewing research outcomes, and setting up investment policies accordingly. Policymakers including government administrations that distribute and manage R&D finance are interested in understanding that the key players are in a given field, how the research clusters are formed, and how the research funding is distributed. Researchers are interested to look at what other researchers are doing and who their potential collaborators are This study proposes a method to provide information wanted by both policymakers and researchers. Based on the proposed method, it builds a knowledge map using the NTIS data to analyze research behavior and statistics of various research topics.