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이윤경,이재명,김원일 慶南大學校 附設 工業技術硏究所 1998 硏究論文集 Vol.15 No.2
신소재인 탄소섬유강화 플라스틱(CFRP)을 피삭재로 선삭가공을 통하여 섬유각의 변화에 따른 절삭저항에 관하여 관찰하였다. 절삭저항은 섬유각 절삭깊이가 클수록 증가하고, 섬유각 15˚ 90˚ 는 절삭속도 40m/min 이상에서 절삭저항이 작아지나, 섬유각 45˚ 60˚ 에서는 절삭속도 40m/min 이상에서 절삭저항이 급격히 증가함을 알 수 있었다. 이송분력이 주분력 배분력보다 거의 2배 가까이 큰것은 섬유의 각도가 클수록 섬유의 방향이 이송방향에 미치는 영향이 크기 때문이라고 생각 된다. CFRP의 최적가공조건은 섬유각 15˚절삭속도 60m min임을 알 수 있다. Carbon Fiber Reinforced Plastic(CFRP), one of the new materials, was investigated about cutting resistance according to the change of fiber angle through in turning Cutting resistance, increases as the fiber angle increases. At the fiber angle of 15˚and 90˚ cutting resistance decreases for the cutting speed more than 40m/min. At the fiber angle of 45˚ and 60˚ cutting resistance increases for the cutting speed less than 40m' min becomes nearly two times the principal force the direction of fiber largely influence upon feed direction. Optimum cutting condition of CFRP can be found to the fiber angle 15˚and cutting speed of 60m/min.
119 구급대원의 노인학대 인식, 신고 및 교육 경험에 관한 연구
채명정,윤종근,김보영,Chae, Myeong-Jeong,Yun, Jong-Geun,Kim, Bo-Young 한국응급구조학회 2017 한국응급구조학회지 Vol.21 No.2
Purpose: The study investigated the perception, report, and education of elder abuse in 119 emergency medical technicians (EMTs) in Korea. Methods: A self-reported questionnaire was distributed to 110 EMTs in K city, and 100 answers were collected from June 1 to 10, 2015. The study instrument was perception regarding elder abuse and education inventory developed by Kim and Kim. Data were analyzed using SPSS/WIN 18.0 version. Results: The elder abuse perception score was 3.81 on a Likert 4-point scale. Physical abuse was the most common type, followed by verbal, financial, negligence, and emotional abuse. Most EMTs recognized that is important for the prevention of elder abuse, but most of them had no experience in reporting abuse. A majority of the EMTs had attended an elder abuse program and recognized the importsnce of such program. Conclusion: This study suggests the necessity of more targeted education of elder abuse prevention combined with family counseling methods and practical approach toward awareness of elder abuse.
Network analysis of drug-related problems in hospitalized patients with hematologic malignancies
Kim, Myeong Gyu,Jeong, Chae Reen,Kim, Hyun Jee,Kim, Jae Hyun,Song, Yun-Kyoung,Kim, Kyung Im,Ji, Eunhee,Yoon, Sung-Soo,Koh, Youngil,Cho, Yoon-Sook,Kim, In-Wha,Oh, Jung Mi Springer-Verlag 2018 SUPPORTIVE CARE IN CANCER Vol.26 No.8
Immunohistochemical detection of LOM strain viral antigens in suckling piglets in Jeju
Jae-Beum Kim(Jae-Beum Kim),Won-Gyu Cho(Won-Gyu Cho),Yun-Ho Kim(Yun-Ho Kim),Hyoung-Nam Jo(Hyoung-Nam Jo),Jae-Sung Heo(Jae-Sung Heo),Myeong-Won Suh(Myeong-Won Suh),Hyoung-Seok Yang(Hyoung-Seok Yang),Wan 한국예방수의학회 2019 한국예방수의학회 학술대회자료집 Vol.2018 No.-
Kim, Yun-Kyung,Son, Ora,Kim, Mi-Ran,Nam, Kyung-Hee,Kim, Gyung-Tac,Lee, Myeong-Sok,Choi, Soon-Young,Cheon, Choong-Ill Research Institute of Women's Health Sookmyung Wom 2007 WOMEN And HEALTH Vol.3 No.1
Homeobox genes are essential regulators of plant development. ATHB23, a class I homeodomain leucine zipper gene of Arabidopsis, was found to be induced by treatment with the phytohormone gibberellin (GA). In order to clarify its role in development, we performed a histochemical analysis of transgenic plants containing a construct with a GUS::GFP reporter under the control of the 1.5 kb upstream region of ATHB23. The construct was mainly expressed in young leaves and the styles of flowers but not in mature leaves. Microscopic examination of young leaves revealed that it was expressed in the adaxial domain of leaf primordia and the rib meristem. Expression of ATHB23, like that of GA5 encoding CA 20-oxidase, was reduced in mutants related to adaxial abaxial leaf polarity (phb-ld, se-2, and kanl kan2). Reduced expression of the GUS::GFP reporter gene was also observed in an se-2 background. These results indicate that ATHB23 is under the control of GA and other activators such as PHB, and is involved in establishing polarity during leaf development.
Yun, Myeong Gu,Ahn, Cheol Hyoun,Cho, Sung Woon,Kim, So Hee,Kim, Ye Kyun,Cho, Hyung Koun American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.11
<P>The effect of multivalent metal cations, including vanadium(V) and tin (Sn), on the electrical properties of vanadium-doped zinc tin oxide (VZTO) was investigated in the context of the fabrication of thin-film transistors (TFTs) using a single VZTO film and VZTO/ZTO bilayer as channel layers. The single VZTO TFT did not show any response to the gate voltage (insulator-like behavior). On the other hand, the VZTO/ZTO bilayer TFT exhibited a typical TFT transfer characteristic (semiconducting behavior). X-ray photoelectron spectroscopy revealed that, in contrast to what is commonly true in many oxides, oxygen vacancies (<inline-formula><mml:math altimg='am-2014-085836_m001.gif' display='inline' overflow='scroll'><mml:msub><mml:mi mathvariant='double-struck'>V</mml:mi><mml:mi mathvariant='normal'>O</mml:mi></mml:msub></mml:math></inline-formula>) in VZTO did not provide a dominant contribution to the total carrier concentration, because the <inline-formula><mml:math altimg='am-2014-085836_m002.gif' display='inline' overflow='scroll'><mml:msub><mml:mi mathvariant='double-struck'>V</mml:mi><mml:mi mathvariant='normal'>O</mml:mi></mml:msub></mml:math></inline-formula> peak area in the single VZTO film was 5.4% and reduced to 4.5% in VZTO/ZTO bilayer. Instead, Sn 3d<SUB>5/2</SUB> and V 2p<SUB>3/2</SUB> spectra suggest that the significant reduction in Sn and V ions is strongly related to the insulator-like behavior of the VZTO film. In negative-bias illumination tests and illumination tests with various photon energies, the VZTO/ZTO bilayer TFT had much better stability than the ZTO TFT. This result is attributed to the reduction of donor-like states (<inline-formula><mml:math altimg='am-2014-085836_m003.gif' display='inline' overflow='scroll'><mml:mi mathvariant='double-struck'>V</mml:mi></mml:math></inline-formula><SUB>O</SUB>) that can be positively ionized by blue and green illumination.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2015/aamick.2015.7.issue-11/am5085836/production/images/medium/am-2014-085836_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am5085836'>ACS Electronic Supporting Info</A></P>
Kim, Youngmi,Kim, Hyuna,Park, Hyunmi,Park, Deokbum,Lee, Hansoo,Lee, Yun Sil,Choe, Jongseon,Kim, Young Myeong,Jeoung, Dooil American Society for Biochemistry and Molecular Bi 2014 The Journal of biological chemistry Vol.289 No.40
<P>Histone modification is known to be associated with multidrug resistance phenotypes. Cancer cell lines that are resistant or have been made resistant to anti-cancer drugs showed lower expression levels of histone deacetylase-3 (HDAC3), among the histone deacetylase(s), than cancer cell lines that were sensitive to anti-cancer drugs. Celastrol and Taxol decreased the expression of HDAC3 in cancer cell lines sensitive to anti-cancer drugs. HDAC3 negatively regulated the invasion, migration, and anchorage-independent growth of cancer cells. HDAC3 conferred sensitivity to anti-cancer drugs <I>in vitro</I> and <I>in vivo</I>. TargetScan analysis predicted <I>miR-326</I> as a negative regulator of HDAC3. ChIP assays and luciferase assays showed a negative feedback loop between HDAC3 and <I>miR-326. miR-326</I> decreased the apoptotic effect of anti-cancer drugs, and the <I>miR-326</I> inhibitor increased the apoptotic effect of anti-cancer drugs. <I>miR-326</I> enhanced the invasion and migration potential of cancer cells. The <I>miR-326</I> inhibitor negatively regulated the tumorigenic, metastatic, and angiogenic potential of anti-cancer drug-resistant cancer cells. HDAC3 showed a positive feedback loop with miRNAs such as <I>miR-200b</I>, <I>miR-217</I>, and <I>miR-335. miR-200b</I>, <I>miR-217</I>, and <I>miR-335</I> negatively regulated the expression of <I>miR-326</I> and the invasion and migration potential of cancer cells while enhancing the apoptotic effect of anti-cancer drugs. TargetScan analysis predicted <I>miR-200b</I> and <I>miR-217</I> as negative regulators of cancer-associated gene, a cancer/testis antigen, which is known to regulate the response to anti-cancer drugs. HDAC3 and <I>miR-326</I> acted upstream of the cancer-associated gene. Thus, we show that the miR-326-HDAC3 feedback loop can be employed as a target for the development of anti-cancer therapeutics.</P>