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        Detection of Methanol in Power Transformer Oil Using Spectroscopy

        Qiang Fu,Lei Peng,Li Li,Musong Lin,Yaohong Zhao,Shengli Li,Chen Chen 대한전기학회 2019 Journal of Electrical Engineering & Technology Vol.14 No.2

        Oil-paper insulation in transformers plays an important role in the operation of power grid. At present, the aging (life assessment) of transformers are mainly conducted based upon the degree of polymerization, concentration of furfural, and the gas analysis of CO and CO 2 in the transformer oil. However, these techniques lack sensitive response, especially in the early aging of oil-paper insulation. Methanol as a new indicator to evaluate the aging of insulating paper, is getting more and more attention. An evaluation method based on the measurement of methanol concentration using ultraviolet–visible spectrometer was proposed in this work. After the extraction from transformer oils, the methanol was oxidized using potassium permanganate. Then, chromotropic acid was used to react with the oxidation products (formaldehyde) to form a mauve clathrate, fi nally, the methanol content was measured using the spectroscopy. Diff erent from traditional spectroscopy which calculate only by absorbance at the characteristic wavelength, this paper use the partial least squares method, obtain the relationship between the absorbance at selected regions and the concentration of methanol. The minimum detection limit for the proposed method was 10 ppb, whereas the correlation coeffi cient for the relationship between the absorbance and the concentration of methanol was as high as 0.99.

      • Association between P478S polymorphism of the filaggrin gene & atopic dermatitis

        Kim, Seon-Young,Yang, Sung Wan,Kim, Hye-Lin,Kim, Sung-Hoon,Kim, Seong Joon,Park, Sun-Min,Son, Musong,Ryu, Sahyun,Pyo, Young-Seok,Lee, Jae-Seok,Kim, Kyu Seok,Kim, Yoon Bum,Hong, Seung-Heon,Um, Jae-Youn Medknow PublicationsMedia Pvt Ltd 2013 The Indian journal of medical research Vol.138 No.6

        <P><B>Background & objectives:</B></P><P>Atopic diseases, including atopic dermatitis (AD), allergy and asthma, are complex diseases resulting from the effect of multiple genetic and interacting environmental factors on their pathophysiology. The genetic basis is incompletely understood; however, recent studies have shown an association between loss-of-function variants of the filaggrin gene (<I>FLG</I>) and atopic dermatitis. The aim of this study was to determine whether <I>FLG</I> variants can serve as a predictor for atopic diseases in Korean individuals.</P><P><B>Methods:</B></P><P>A total of 648 subjects were genotyped for the <I>FLG</I> P478S (rs11584340, C/T base change) polymorphism (322 patients and 326 controls). Serum levels of free fatty acids (FFA) and IgE were later stratified to determine the effects of the <I>FLG</I> polymorphism on AD.</P><P><B>Results:</B></P><P>A significant difference in genotype frequency was found between AD patients and controls in the <I>FLG</I> P478S polymorphism. The <I>FLG</I> P478S T allele carrier (TT+TC) was associated with AD risk (odds ratio = 1.877, 95% confidence interval 1.089 to 3.234). In addition, the P478S T allele was related to high levels of FFA in AD patients (471.79 ± 298.96 vs. 333.54 ± 175.82 μg eq/l, <I>P</I> <0.05).</P><P><B>Interpretation & conclusions:</B></P><P>The results of the present study suggest that the <I>FLG</I> P478S polymorphism alone and combined with other factors influences FFA levels and increases the susceptibility to AD.</P>

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