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      • KCI등재

        Intravascular Placement of Metallic Coils as Lung Tumor Markers for CyberKnife Stereotactic Radiation Therapy

        Kutlay Karaman,A. Murat Dokdok,Oktay Karadeniz,Cemile Ceylan,Kayıhan Engin 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.3

        To present our experience with placing endovascular coils in pulmonary arteries used as a fiducial marker for CyberKnife therapy and to describe the technical details and complications of the procedure. Between June 2005 and September 2013, 163 patients with primary or secondary lung malignancies, referred for fiducial placement for stereotactic radiosurgery, were retrospectively reviewed. Fourteen patients (9 men, 5 women; mean age, 70 years) with a history of pneumonectomy (n = 3), lobectomy (n = 3) or with severe cardiopulmonary co-morbidity (n = 8) underwent coil (fiducial marker) placement. Pushable or detachable platinum micro coils (n = 49) 2–3 mm in size were inserted through coaxial microcatheters into a small distal pulmonary artery in the vicinity of the tumor under biplane angiography/fluoroscopy guidance. Forty nine coils with a median number of 3 coils per tumor were placed with a mean tumor-coil distance of 2.7 cm. Forty three (87.7%) of 49 coils were successfully used as fiducial markers. Two coils could not be used due to a larger tumor-coil distance (> 50 mm). Four coils were in an acceptable position but their non-coiling shape precluded tumor tracking for CyberKnife treatment. No major complications needing further medication other than nominal therapy, hospitalization more than one night or permanent adverse sequale were observed. Endovascular placement of coil as a fiducial marker is safe and feasible during CyberKnife therapy, and might be an option for the patients in which percutaneous transthoracic fiducial placement might be risky.

      • KCI등재

        Prediction of force reduction factor (R) of prefabricated industrial buildings using neural networks

        M. Hakan Arslan,Murat Ceylan,M. Yasar Kaltakci,Yüksel Ozbay,Fatma Gulten Gulay 국제구조공학회 2007 Structural Engineering and Mechanics, An Int'l Jou Vol.27 No.2

        The force (load) reduction factor, R, which is one of the most important parameters in earthquake load calculation, is independent of the dimensions of the structure but is defined on the basis of the load bearing system of the structure as defined in earthquake codes. Significant damages and failures were experienced on prefabricated reinforced concrete structures during the last three major earthquakes in Turkey (Adana 1998, Kocaeli 1999, Duzce 1999) and the experts are still discussing the main reasons of those failures. Most of them agreed that they resulted mainly from the earthquake force reduction factor, R that is incorrectly selected during design processes, in addition to all other detailing errors. Thus this wide spread damages caused by the earthquake to prefabricated structures aroused suspicion about the correctness of the R coefficient recommended in the current Turkish Earthquake Codes (TEC - 98). In this study, an attempt was made for an approximate determination of R coefficient for widely utilized prefabricated structure types (single-floor single-span) with variable dimensions. According to the selecting variable dimensions, 140 sample frames were computed using pushover analysis. The force reduction factor R was calculated by load-displacement curves obtained pushover analysis for each frame. Then, formulated artificial neural network method was trained by using 107 of the 140 sample frames. For the training various algorithms were used. The method was applied and used for the prediction of the R rest 33 frames with about 92% accuracy. The paper also aims at proposing the authorities to change the R coefficient values predicted in TEC - 98 for prefabricated concrete structures.

      • SCIESCOPUS

        Prediction of force reduction factor (R) of prefabricated industrial buildings using neural networks

        Arslan, M. Hakan,Ceylan, Murat,Kaltakci, Yaspr M.,Ozbay, Yuksel,Gulay, Fatma Gulten Techno-Press 2007 Structural Engineering and Mechanics, An Int'l Jou Vol.27 No.2

        The force (load) reduction factor, R, which is one of the most important parameters in earthquake load calculation, is independent of the dimensions of the structure but is defined on the basis of the load bearing system of the structure as defined in earthquake codes. Significant damages and failures were experienced on prefabricated reinforced concrete structures during the last three major earthquakes in Turkey (Adana 1998, Kocaeli 1999, Duzce 1999) and the experts are still discussing the main reasons of those failures. Most of them agreed that they resulted mainly from the earthquake force reduction factor, R that is incorrectly selected during design processes, in addition to all other detailing errors. Thus this wide spread damages caused by the earthquake to prefabricated structures aroused suspicion about the correctness of the R coefficient recommended in the current Turkish Earthquake Codes (TEC - 98). In this study, an attempt was made for an approximate determination of R coefficient for widely utilized prefabricated structure types (single-floor single-span) with variable dimensions. According to the selecting variable dimensions, 140 sample frames were computed using pushover analysis. The force reduction factor R was calculated by load-displacement curves obtained pushover analysis for each frame. Then, formulated artificial neural network method was trained by using 107 of the 140 sample frames. For the training various algorithms were used. The method was applied and used for the prediction of the R rest 33 frames with about 92% accuracy. The paper also aims at proposing the authorities to change the R coefficient values predicted in TEC - 98 for prefabricated concrete structures.

      • SCOPUSKCI등재

        Dual trigger in normally-responding assisted reproductive technology patients increases the number of top-quality embryos

        Sukur, Yavuz Emre,Ulubasoglu, Hasan,Ilhan, Fatma Ceylan,Berker, Bulent,Sonmezer, Murat,Atabekoglu, Cem Somer,Aytac, Rusen,Ozmen, Batuhan The Korean Society for Reproductive Medicine 2020 Clinical and Experimental Reproductive Medicine Vol.47 No.4

        Objective: The feasibility of a gonadotropin-releasing hormone agonist (GnRHa) trigger in normal responders is still a matter of debate. The aim of this study was to compare the number of mature oocytes, the number of good-quality embryos, and the live birth rate in normal responders triggered by GnRHa alone, GnRHa and human chorionic gonadotropin (hCG; a dual trigger), and hCG alone. Methods: A retrospective cohort study was conducted at the infertility clinic of a university hospital. Data from 200 normal responders who underwent controlled ovarian hyperstimulation and intracytoplasmic sperm injection with a GnRH antagonist protocol between January 2016 and January 2017 were reviewed. The first study group consisted of patients with cycles triggered by GnRHa alone. The second study group consisted of patients with cycles triggered by both GnRHa and low-dose hCG (a dual trigger). The control group consisted of patients with cycles triggered by hCG alone. Results: The groups were comparable in terms of demographics and cycle characteristics. The numbers of total oocytes retrieved and metaphase II oocytes were similar between the groups. The total numbers of top-quality embryos were 3.2±2.9 in the GnRHa group, 4.4±3.2 in the dual-trigger group, and 2.9±2.1 in the hCG group (p=0.014). The live birth rates were 21.4%, 30.5%, and 28.2% in those groups, respectively (p=0.126). Conclusion: In normal responders, a dual-trigger approach appears superior to an hCG trigger alone with regard to the number of top-quality embryos produced. However, no clinical benefit was apparent in terms of live birth rates.

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