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Metabolites of Marine Algae Collected from Karachi-coasts of Arabian Sea
Muhammad Shaiq Ali,Muhammad Jahangir,Muhammad Saleem,Muhammad Kashif Pervez,Shaista Hameed,Viqar Uddin Ahmad 한국생약학회 2000 Natural Product Sciences Vol.6 No.2
The ethanolic extracts of marine green, brown and red algae collected from Karachi coasts of Arabian Sea afforded a new enol-derivative of N-acylsphingosine named as coelarthenol (1) from Coelarthrum muelleri, two new glucose-derivatives named: botryenal (2) and botryenol (3) from Botryocladia leptopoda, α-tocopherol quinone (4) from Codium iyengarii, β-sitosterol and hexadecanoic acid from Stokeyia indica. The known constituents (4, β-sitosterol & hexadecanoic acid) have not been reported so far from their corresponding sources and the structures were determined through spectroscopic methods, whereas, the structures of new constituents (1-3) were elucidated with the aid of selective HMBC experiments. The phytotoxicity of 4 was also monitored.
Chemical Constituents of Pulicaria gnaphalodes
Muhammad Shaiq Ali,Muhammad Jahangir,Muhammad Saleem,Viqar Uddin Ahmad 한국생약학회 1999 Natural Product Sciences Vol.5 No.3
The chloroform extract of Pulicaria gnaphalodes yielded flavonoids (1-2), sesquiterpenoid (3), sterol (4), benzoic acid derivative (5) and fatty acids (6-7). Their structures were elucidated with the aid of NMR spectroscopy. The described compounds have not been reported so far from this source.
Salvatrione : A Diterpene-monoterpene Conjugate from Salvia bucharica
Viqar Uddin Ahmad,Muhammad Zahid,Muhammad Shaiq Ali,Amir Reza Jassbi,Shakeel Ahmad,Zulfiqar Ali,Muhammad Zafar Iqbal 한국생약학회 2000 Natural Product Sciences Vol.6 No.2
Salvia bucharica belonging to the family Lamiaceae (Labiatae), afforded a novel terpenoid (1) named as salvatrione. The structure of 1 was elucidated through extensive 2-D NMR experiments and the biogenetic pathway of 1 has also been proposed. On biogenetic grounds, 1 may be considered to be a pseudo-triterpenoid as it is derived from the coupling of mono/diterpenic units and not from squalene.
ChemInform Abstract: Antimicrobial Natural Products: An Update on Future Antibiotic Drug Candidates
Saleem, Muhammad,Nazir, Mamona,Ali, Muhammad Shaiq,Hussain, Hidayat,Lee, Yong Sup,Riaz, Naheed,Jabbar, Abdul WILEY-VCH Verlag 2010 Chem Inform Vol.41 No.21
<P>ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.</P>
Data Science and Machine Learning Approach to Improve E-Commerce Sales Performance on Social Web
Hussain Saleem,Khalid Bin Muhammad,Altaf H. Nizamani,Samina Saleem,M. Khawaja Shaiq Uddin,Syed Habib-ur-Rehman,Amin Lalani,Ali Muhammad Aslam International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.8
E-Commerce is a buzzword well known for electronic commerce activities including but not limited to the online shopping, digital payment transactions, and B2B online trading. In today's digital age, e-commerce has been playing a very important and vital role in areas such as retail shopping, sales automation, supply chain management, marketing and advertisement, and payment services. With a huge amount of data been collected from various e-commerce services available, there are multiple opportunities to use that data to analyze graphs and trends. Strategize profitable activities, and forecast future trade. This paper explains a contemporary approach for collecting key data metrics and implementing cost-effective automation that will support in improving conversion rates and sales performance of the e-commerce websites resulting in increased profitability.
Brahol : A New Derivative of allo-Inositol from Stocksia brahuica
Yiqar Uddin Ahmad,Zulfiqar Ali,Muhammad Shaiq Ali,Muhammad Zahid,Rasool Bakhsh Tareen 한국생약학회 1998 Natural Product Sciences Vol.4 No.3
A new derivative of allo-inosital has been isolated from the aerial parts of Stocksia brahuica and named as brahol (1). The structure of 1 was elucidated with the help of extensive 2D-NMR spectroscopic techniques and identified as 5-O-methyl-allo-inositol. The structure was reconfirmed by acetate derivative (2).
Hermann Marius Feumo Feusso,Hermann Marius Feumo Feusso,Hermine Laure Maza Djomkam,Carine Mvot Akak,Mehreen Lateef,Ayaz Ahmed,Anatole Guy Blaise Azebaze,Alain François Kamdem Waffo,Muhammad Shaiq Ali 한국생약학회 2020 Natural Product Sciences Vol.26 No.4
The chemical investigation of the methanolic crude extract of leaves of Diospyros iturensis gave us 15 known secondary metabolites identified as mixture of α-amyrenone (1) and β-amyrenone (2), b-amyrin (3), mixture of β-sitosterol (4) and stigmasterol (5), betulin (6), uvaol (7), betulinic acid (8), ursolic acid (9), corosolic acid (10), actinidic acid (11),11-O-p-hydroxybenzoylbergenin (12), bergenin (13) and mixture of stigmasterol glucoside (14) and β-sitosterol glucoside (15) respectively. The structures of secondary metabolites were elucidated with the help of NMR and mass spectral data and by comparison of their spectral data with literature. Among the fifteen isolated compounds, four compounds were identified for the first time in Diospyros genus. These included uvaol (7), corosolic acid (10), actinidic acid (11) and 11-O-p-hydroxybenzoylbergenin (12). Crude methanolic extract of leaves and four isolated compounds including betulin (6), betulinic acid (8), 11-O-p-hydroxybenzoylbergenin (12) and bergenin (13) were evaluated for their antiproliferative activity against two cancer cell lines CAL-27 and NCI-H460 by the MTT assay, antioxidant potential and inhibitory activity against the lipoxygenase and urease enzymes, respectively. The results indicated that the methanolic crude extract of leaves exhibited moderate antioxidant activity and was inactive against the two cancer cell lines. Betulin (6), 11-O-p-hydroxybenzoylbergenin (12) and bergenin (13) exhibited moderate antioxidant and lipoxygenase inhibition with IC50 = 65.8, 85.6, 82.5 µM and IC50 = 58.5, 95.2, 76.2 µM, respectively. Furthermore, 11-O-p-hydroxyben- zoylbergenin (12) and bergenin (13) exhibited moderate urease inhibition activity with IC50 values of 45.6 µM and 49.8 µM, respectively.