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- 저자 : Morteza Seifi (검색결과 2 건)
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Sadegh Etedali,Mohammad Seifi,Morteza Akbari 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.85 No.3
The seismic performance of the tall building equipped with a tuned mass damper (TMD) considering soil-structure interaction (SSI) effects is well studied in the literature. However, these studies are performed on the nominal model of the seismic-excited structural system with SSI. Hence, the outcomes of the studies may not valid for the actual structural system. To address the study gap, the reliability theory as a useful and powerful method is utilized in the paper. The present study aims to carry out reliability analyses on tall buildings equipped with TMD under near‐field pulse-like (NFPL) ground motions considering SSI effects using a subset simulation (SS) method. In the presence of uncertainties of the structural model, TMD device, foundation, soil, and near‐field pulse-like ground motions, the numerical studies are performed on a benchmark 40-story building and the failure probabilities of the structures with and without TMD are evaluated. Three types of soils (dense, medium, and soft soils), different earthquake magnitudes ( = 7,0. 7,25. 7,5 ), different nearest fault distances ( = 5. 10 and 15 km), and three seismic performance levels of immediate occupancy (IO), life safety (LS), and collapse prevention (CP) are considered in this study. The results show that tall buildings built near faults and on soft soils are more affected by uncertainties of the structural and ground motion models. Hence, ignoring these uncertainties may result in an inaccurate estimation of the maximum seismic responses. Also, it is found the TMD is not able to reduce the failure probabilities of the structure in the IO seismic performance level, especially for high earthquake magnitudes and structures built near the fault. However, TMD is significantly effective in the reduction of failure probability for the LS and CP performance levels. For weak earthquakes and long fault distances, the failure probabilities of both structures with and without TMD are near zero, and the efficiency of the TMD in the reduction of failure probabilities is reduced by increasing earthquake magnitudes and the reduction of fault distance. As soil softness increases, the failure probability of structures both with and without TMD often increases, especially for severe near-fault earthquake motion.
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Sara Haratizadeh,Maryam Nazm Bojnordi,Shahram Darabi,Narges Karimi,Mehrdad Naghikhani,Hatef Ghasemi Hamidabadi,Morteza Seifi 대한해부학회 2017 Anatomy & Cell Biology Vol.50 No.2
Cerebrospinal fluid (CSF) contains several molecules which are essential for neurogenesis. Human dental pulp stem cells (hDPSCs) are putatively neural crest cell-derived that can differentiate into neurons and glial cells under appropriate neurotrophic factors. The aim of this study was to induce differentiation of hDPSCs into neuroglial phenotypes using retinoic acid (RA) and CSF. The hDPSCs from an impacted third molar were isolated by mechanical and digestion and cultured. The cells have treated by 10 –7 μM RA (RA group) for 8 days, 10% CSF (CSF group) for 8 days and RA with CSF for 8 days (RA/ CSF group). Nestin, microtubule-associated protein 2 (MAP2), and glial fibrillary acidic protein immunostaining were used to examine the differentiated cells. Axonal outgrowth was detected using Bielschowsky’s silver impregnation method and Nissl bodies were stained in differentiated cells by Cresyl violet. The morphology of differentiated cells in treated groups was significantly changed after 3–5 days. The results of immunocytochemistry showed the presence of neuroprogenitor marker nestin was seen in all groups. However, the high percentage of nestin positive cells and MAP2, as mature neural markers, were observed at the pre-induction and induction stage, respectively. Nissl bodies were detected as dark-blue particles in the cytoplasm of treated cells. Our findings showed the RA as pre-inducer and CSF as inducer for using in vitro differentiation of neuron-like cells and neuroglial cells from hDPSCs.
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