Bio-recovery of municipal plastic waste management based on an integrated decision-making framework

Mohammad M. Shahsavar,Mehran Akrami,Zahra Kian,Mohammad Gheibi,Amir M. Fathollahi-Fard,Mostafa Hajiaghaei-Keshteli,Kourosh Behzadian 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.108 No.-

Recent years have seen a rapid development in industrialization and urbanization with a huge growth inthe population throughout the world. In this regard, an efficient and robust decision-making frameworkfor the concept of a green city and sustainable development goals to manage municipal plastic wastes isstill needed. This study models a bio-recovery of municipal different plastic wastes management basedon a new integrated Multi-Criterion Decision-Making (MCDM) approach through a case study inMashahd, Iran. The proposed integrated MCDM framework includes the Shannon Entropy (SE),Ordered Weighted Aggregation (OWA), Analytic Hierarchy Process (AHP), Technique for OrderPreference by Similarity to Ideal Solution (TOPSIS) and, ELimination Et Choice Translating REality(ELECTRE) systems in an intelligent way. Through decision-making computations, all criteria areapproved after extraction from the literature review by experts with more than 60% agreement percentage. Different scenarios of economic, energy, and environmental crises are created. One finding of thispaper is to propose a new entrance in economic competition with plastic biodegradation to present anovel, environmental-friendly product with high-quality and low-cost advantages. Another findingdetermines that with an application of plastic wastes bio-recovery, citizens’ satisfaction from urban managementsystem will be increased from 49% to 64%. Whereas, based on the outcomes of this investigation,the rate of municipal waste industries development, smart city goals’ meeting, and rate of hazardousmaterial emission from municipal solid wastes are increased to 58%, 25%, and 70%, respectively. Thedeclared numerical outcomes illustrate the effectiveness of plastic waste bio-recovery on the smart cityconcept.

Wheat Seedlings Urease Activity as Affected by Nickel and Nitrogen Sources

Mohammad Nabi Gheibi 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

The Impact of Abuse on the Quality of Life of the Elderly: A Population-based Survey in Iran

Honarvar, Behnam,Gheibi, Zahra,Asadollahi, Abdolrahim,Bahadori, Farzaneh,Khaksar, Elahe,Faradonbeh, Maryam Rabiey,Farjami, Mohammad The Korean Society for Preventive Medicine 2020 Journal of Preventive Medicine and Public Health Vol.53 No.2

Objectives: The quality of life (QoL) of the elderly and elder abuse are growing public health concerns. This study aimed to evaluate the prevalence of abuse and the association between QoL and abuse in older adults. Methods: Multistage random cluster sampling, along with valid QoL (LEIPAD: LEIden, the Netherlands; PADua, Italy; Helsinki, Finland) and abuse questionnaires, were used to assess QoL and elder abuse. Path analysis was performed using Mplus. SPSS and AMOS were used for the other analyses. Results: A total of 386 elderly individuals with a mean age of 68.00±6.10 years were interviewed, of whom 200 (51.8%), 289 (74.9%), and 376 (97.4%) were women, educated, and married, respectively. Moreover, 167 (43.2%) had low-to-moderate QoL, and 108 (27.9%) had experienced a moderate level of abuse. QoL and abuse were inversely associated (r=-0.253), with men (β=-0.24) more affected than women (β=-0.21). Musculoskeletal disorders were also strong determinants of QoL in the elderly. QoL was strongly associated with emotional abuse, while abuse was highly related to the social component of QoL. Furthermore, emotional abuse was the type of abuse most significantly associated with the self-care, depression/anxiety, cognitive, and social components of QoL. Sexual abuse, violation of personal rights, and neglect were the main determinants of the physical functioning, life satisfaction, and sexual domains of QoL, respectively. Conclusions: Nearly half of the elderly individuals lacked a high QoL, and at least one-fourth had experienced some form of abuse. Elder abuse was correlated inversely with QoL. Therefore, preventive interventions are recommended to decrease elder abuse in the family, community, and other settings.

Differential Expression of HSP90 in MDA-MB-231 and MCF-7 Cell Lines after Treatment with Doxorubicin

Fereshte Jokar,Javad Amini Mahabadi,Morteza Salimian,Ali Akbar Taherian,Seyyed Mohammad Gheibi Hayat,Amirhossein Sahebkar,Mohammad Ali Atlasi 대한약침학회 2019 Journal of pharmacopuncture Vol.22 No.1

Background: Breast cancer is a complex, heterogeneous disease and one of the most common malignancies in women worldwide. The efficacy of chemotherapy as an important breast cancer treatment option has been severely limited because of the inherent or acquired resistance of cancer cells. The molecular chaperone heat shock protein 90 (HSP90) upregulated in response to cellular stress is required for functions such as conformational maturation, activation and stability in more than 200 client proteins, mostly of the signaling type. In this study, the expression of HSP90 isoforms including HSP90α and HSP90 in breast cancer cell lines before and after treatment with doxorubicin (DOX) was assessed. Material and Methods: The cell cytotoxicity of DOX in MDA-MB-231 and MCF-7 cell lines was determined using the MTT assay. Immunofluorescence and western blotting techniques were used to determine the expression of HSP90 in the cell lines before and after DOX treatment. Immunofluorescence was also conducted to ascertain the expression of HSP90α. Results: The MTT assay results showed that the MDAMB-231 cells (IC 50 =14.521 μМ) were more sensitive than the MCF-7 cells (IC 50 =16.3315 μМ) to DOX. The immunofluorescence results indicated that the expression of HSP90α in both cell lines decreased after exposure to DOX. The western blot and immunofluorescence analyses showed that HSP90 expression decreased in the MCF-7 cells but increased in the MDAMB-231 cells after DOX treatment. Conclusion: The obtained results suggested that HSP90α and HSP90 expression levels were reduced in the MCF-7 cells after exposure to DOX. In the MDA-MB-231 cells, HSP90α expression was reduced while HSP90 was found to be overexpressed following DOX treatment.

Differential Expression of HSP90β in MDA-MB-231 and MCF-7 Cell Lines after Treatment with Doxorubicin

Jokar, Fereshte,Mahabadi, Javad Amini,Salimian, Morteza,Taherian, Aliakbar,Hayat, Seyyed Mohammad Gheibi,Sahebkar, Amirhossein,Atlasi, Mohammad Ali KOREAN PHARMACOPUNCTURE INSTITUTE 2019 Journal of pharmacopuncture Vol.22 No.1

Background: Breast cancer is a complex, heterogeneous disease and one of the most common malignancies in women worldwide. The efficacy of chemotherapy as an important breast cancer treatment option has been severely limited because of the inherent or acquired resistance of cancer cells. The molecular chaperone heat shock protein 90 (HSP90) upregulated in response to cellular stress is required for functions such as conformational maturation, activation and stability in more than 200 client proteins, mostly of the signaling type. In this study, the expression of HSP90 isoforms including $HSP90{\alpha}$ and $HSP90{\beta}$ in breast cancer cell lines before and after treatment with doxorubicin (DOX) was assessed. Material and Methods: The cell cytotoxicity of DOX in MDA-MB-231 and MCF-7 cell lines was determined using the MTT assay. immunofluorescence and western blotting techniques were used to determine the expression of $HSP90{\beta}$ in the cell lines before and after DOX treatment. Immunofluorescence was also conducted to ascertain the expression of $HSP90{\alpha}$. Results: The MTT assay results showed that the MDA-MB-231 cells ($IC_{50}=14.521{\mu}M$) were more sensitive than the MCF-7 cells ($IC_{50}=16.3315{\mu}M$) to DOX. The immunofluorescence results indicated that the expression of $HSP90{\alpha}$ in both cell lines decreased after exposure to DOX. The western blot and immunofluorescence analyses showed that $HSP90{\beta}$ expression decreased in the MCF-7 cells but increased in the MDA-MB-231 cells after DOX treatment. Conclusion: The obtained results suggested that $HSP90{\alpha}$ and $HSP90{\beta}$ expression levels were reduced in the MCF-7 cells after exposure to DOX. In the MDA-MB-231 cells, $HSP90{\alpha}$ expression was reduced while $HSP90{\beta}$ was found to be overexpressed following DOX treatment.