http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Encapsulation of Frankincense Essential Oil by Microfluidic and Bulk Approaches: A Comparative Study
Pouria Taherian,Mohammad Sadegh Nourbakhsh,Ali Abouei Mehrizi,Mohadeseh Hashemi 한국섬유공학회 2022 Fibers and polymers Vol.23 No.10
Herbs and hand-made herbal remedies have been long used for disease control, treatment, and healthimprovement. Evidence suggests that a single herb's compounds can have synergistic functions with probably no adverseeffect. Unfortunately, the traditional administration of essential oil (EO) does not follow a regulatory dose regimen, causingreduced bioavailability due to EO evaporation or denaturation in harsh biological environments. Hence, encapsulation canhelp enhance EO stability and dose dependence. Here, chitosan nanoparticles (ChNPs) were used to encapsulate frankincenseessential oil (FEO) to preserve its remarkable therapeutic effects. Also, traditional bulk preparation methods were comparedwith microfluidic with central aqueous stream configuration (CAS). The results indicated the higher quality of microfluidicbasednanoparticles with uniform, spherical, and separated morphologies. The size of bulk and microfluidic nanoparticlesranged from 86 to 118 nm, the surface charge varied from 12.5 to 19.5 for different amounts of FEO, and the as-preparedcolloid remained stable for three days. Narrow size distribution (PDI0.28) and high encapsulation efficiency (EE99 %)were achieved using the microfluidic process compared to the bulk method (PDI=0.74, EE90 %). The microfluidicnanoparticle also indicated a burst release rate greater than the bulk method (30 %). It was concluded that the highperformancemicrofluidic approach provided higher quality and more control over nanoparticle properties.