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자연의 아름다움과 고급스러움이 공존하는 마임 비에타 쇼룸 제안 -오감 (시각, 청각, 후각, 촉각, 미각)을 중심으로-
김보현,이서연,은다솜,엄연정,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-
본 연구는 국내 브랜드 ‘마임'의 뷰티와 연계한 뷰티 쇼룸을 제안함에 있어서 공간속에 오감을 담아내는 일련의 프로세스를 밝히는데 목적이 있다. 이는 브랜드가 소유하고 있는 다양한 감각과 가치가 결여된 채 시각적 요소만이 담긴 브랜드 뷰티 쇼룸이 대다수를 차지하는 오늘날, 이에 대한 문제를 해결하기 위해 ’융합 연출 디자인'적 시점에서 폭넓게 바라보고 브랜드의 정신과 오감의 결합을 통해 이를 해결하고자 하였다. 이에 본 연구는 2017년 3월~6월 15주간 숙명여대 환경디자인학과 <융합연출 디자인>수업에서 진행된 수업의 결과물로서 산학 연계된 화장품 브랜드의 쇼룸디자인 개발 프로세스를 제안한다. 또한 본 연구의 범위는 오감을 담고 있는 뷰티 쇼룸(4D)이 되기까지의 과정 전체로 한다. 그 결과, 마임 뷰티쇼룸은 공간 디자인과 오감을 융합하여 영상에서 공간에 이르기까지 오감의 조화와 브랜드의 정신을 녹여내고 확장시켰다. 끝으로 본 연구는 뷰티 쇼룸 공간 디자인을 제안함에 있어서 오감을 활용하여 통합된 시점에서 그래픽·제품·공간을 개발 및 제시한 것에 의의가 있다. 또한 향후 이와 관련된 쇼룸 공간 개발에 있어서 기초 자료로 활용될 것으로 기대된다.
가스크로마토그래피를 이용한 요중 마뇨산 측정시 새로운 시료 전처리 방법의 검증
조수현,임용현,김선민,권호장,하미나,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1
Urinary hippuric acid was analyzed by gas chromatography/mass spectrometry method. A simple and economical derivatization procedure using excessive methanol in acidic condition was adopted to esterify hippuric acid. Quantitative analysis was performed with two internal standards, heptadecanoic acid and hydrocinnamic acid, to evaluate the derivatization procedure as an analytical method. Using the standard addition method, linear and reproducible calibration curves were obtained for both internal standards. Calibration experiment showed that good quantitative result could also be obtained with the calibration curve obtained without urine matrix. Recovery rates for the urine samples were in the range of 95.6∼111.4%. Using hydrocinnamic acid as internal standard, analysis time could be reduced.
Protective effect of dohongsamul-tang on cardiac function in myocardial infarct injury rats
Youn Jae Jang,Se Won Na,Hye yoom Kim,Mi Hyeon Hong,Jung Joo Yoon,Ho Sub Lee,Dae Gill Kang 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7
Myocardial infarction (MI) is frequent and severe manifestation of ischemic heart disease. Post-MI activated fibroblasts increase their motility and migrate into the lesion. The frequent outcome of these processes is adverse cardiac remodeling and dysfunction, ultimately leading to heart failure (1). Dohongsamul-tang (桃紅四物湯, DHT), which commonly was used to for relieve women"s irregular menses disorder, and is also used to treat immunological disorders, migraine, and cardiovascular diseases such as hypertension and angina (2-3). The present study investigates the effect of DHT on MI injury. DHT was initially administered post occlusion, followed was administered for 8 weeks. To simulate the clinical settings of MI followed by therapy, I employed a rat model of left anterior descending artery occlusion for 8 weeks following. Furthermore, myocardial infarct size assessed using triphenyl tetrazolium chloride staining, and after MI, the infarct size in the DHT treatment group decreased compared to the MI group. The serum activity levels of cardiac enzymes, including creatine kinase and lactate dehydrogenase, were evaluated using the serum. Cardiac performance and remodeling were evaluated by using conventional echocardiography methods, hemodynamic measurements pressure-volume loop, and histopathological techniques. DHT administration markedly decreased the remodeling process, as illustrated by attenuation of left ventricular enlargement and cardiac hypertrophy both at the whole heart and the cellular level. Furthermore, Fibrosis reduced by the treatment of DHT. Functionally echocardiography and hemodynamic measurements were significantly improved by DTH. Furthermore, the color changes of Masson"s trichrome and Picrosirius" red staining. These findings indicate that DHT provides cardioprotection against the post-MI remodeling model.
Jang, Mi-Hyeon,Kim, Hong,Shin, Min-Chul,Lim, Baek-Vin,Lee, Taeck-Hyun,Jung, Sae-Bin,Kim, Chang-Ju,Kim, Ee-Hwa WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2002 東西醫學硏究所 論文集 Vol.2002 No.-
ABSTRACT-Folium mori, the leaves of Morus alba L., has traditionally been used for the treatment of diabetic hyperglycemia. It has been shown to induce enhanced NOS expression in the hypothalamus of rats with streptozotocin(S72)-induced diabetes. In the present study, the effect of Folium mori on the expression of nitric oxide synthase (NOS) in the hypothalamus of STZ-induced diabetic rats was investigated via nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) histochemlstry. Enhanced NAPDH-d expression was detected in the paraventncular nucleus, ventromedial hypothalamic nucleus, and lateral hypo-thalamic area of the hypothalamus in the STZ-induced diabetes group. Administration of the aqueous extract of Folium mori to rats with STZ-induced diabetes resulted in decreased NADPH-d positivity. These results suggest that Folium mori treatment is effective in curbing the desire for food under diabetic conditions via modulation of NO expression in the hypothalamus.