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Shiliang Wang,Hua Zhong,Meijuan Lu,Guohua Song,Xiaomei Zhang,Min Lin,Shengliang Yang,Mincai Qian 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.8
Objective_The pathogenesis of depression is not fully understood yet, but studies have suggested higher circulating C reactive protein (CRP) level might relate to depression occurrence. However, due to high variability of patients’ individual condition, the results to date are inconsistent. Considering CRP single-nucleotide polymorphisms (SNPs) could also regulate plasma CRP levels, in the present study, we hypothesized that inherited CRP allelic variations may co-vary with depressive symptomatology. Methods_We recruited 60 depression patients with family depression history and 60 healthy control volunteers into this project. We detected circulation CRP level as well as genome CRP SNPs from participants of this project. Results_We have found a significantly higher circulating CRP level in patients with a positive family history. Furthermore, we also identified some certain inherited CRP SNPs (A allele in rs1417938 and C allele in rs1205) could up regulate serum CRP level and distributed more in depression patients with family history. Conclusion_Our finding may raise new evidence that genetically increased serum CRP level through SNPs variation is likely to induce family inherited depression.
Bichun Huang,Hansun Fang,Huajun Huang,Meijuan Lu,Chenglong Yu 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.95 No.-
A one-pot synthetic method was used to prepare copper (Cu)-modified manganese (Mn)-rich MnSAPO-34 catalysts, which were then used for NOx removal from stationary-sourceflue gas. The addition of Cu tothese Mn-rich MnSAPO-34 catalysts significantly enhanced their low temperature (LT) selective catalyticreduction (SCR) activity and H2O resistance. The Mn0.4Cu0.05SAPO-34 catalysts demonstrated excellent LTNH3-SCR activity, with NOx removal being >90% from 160 to 300 C. In addition, Mn0.4Cu0.05SAPO-34catalysts exhibited high H2O resistance. This excellent performance was ascribed to strong synergisticeffects between Mn4+ and isolated Cu2+ species in Mn0.4Cu0.05SAPO-34 catalysts, leading to suitable redoxability. The results of in situ FT-IR analysis indicated that LT-SCR reactions mainly proceeded by an Eley–Rideal reaction pathway at 200 C in Cu-modified manganese-rich MnSAPO-34 catalysts. Thus,Mn0.4Cu0.05SAPO-34 was considered as a promising candidate for NOx removal fromflue gas ofstationary sources at low temperatures.