Effect of abdominal acupuncture combined with routine rehabilitation training on shoulder-hand syndrome after stroke: A randomized controlled trial

Zhan Jie,Ai Yirang,Zhan Lechang,Pan Ruihuan,Wang Yiqiao,Dong Cong,Wang Qiuchun,Chen Hongxia,Lu Liming,Li Mei 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

Background: Post-stroke shoulder-hand syndrome (SHS) is a common complication after stroke. To date, there is still a lack of consistently effective and good patient compliance methods for SHS. Methods: Fifty patients with SHS were included in this study. Patients in the control group received rehabilitation training (RT) for 2 weeks; each session was 30 min, 1 time per day, and 5 times per week. Patients in the observation group were additionally given Bo’s abdominal acupuncture (BAA) with the same frequency and duration. The primary outcome was the change value in the VAS score from baseline to 2 weeks. The secondary outcomes measured were motor function of the upper limb, shoulder range of motion, ADL, and swelling volume. Results: Compared with baseline values, the mean VAS score at 2 weeks was reduced by 3.68 in the observation group and by 1.92 in the control group, with a difference between the two groups of 1.84 (P < 0.001); the mean MBI score at 2 weeks increased by 10.44 in the observation group and by 4.79 in the control group, with a difference between the two groups of 5.84 (P = 0.032); the mean swelling volume at 2 weeks decreased by 9.64 in the observation group and by 3.29 in the control group, with a difference between the two groups of 6.48 (P < 0.001). BAA-related adverse events were not found during the study. Conclusions: BAA combined with RT is superior to RT alone in improving shoulder pain, swelling, and ADL in post-stroke SHS patients. Trial Registration: ChiCTR2100045464 (www.chictr.org.cn).

Overexpression of a Lotus corniculatus AP2/ERF transcription factor gene, LcERF080, enhances tolerance to salt stress in transgenic Arabidopsis

Zhan-Min Sun,Yan-Min Wu,Mei-Liang Zhou,Xing-Guo Xiao,Yi-Xiong Tang 한국식물생명공학회 2014 Plant biotechnology reports Vol.8 No.4

The APETALA2/ethylene-responsive elementbinding factors (AP2/ERF) play central roles in the stressresponse in plants. In this study, we identified and isolateda novel salt stress-related gene, LcERF080, that encodes anAP2/ERF protein in Lotus corniculatus cultivar Leo. LcERF080 was classified into the B-4 group of the ERFsubfamily based on multiple sequence alignment andphylogenetic characterization. Expression of LcERF080was strongly induced by salt, abscisic acid, 1-aminocyclopropane-1-carboxylic acid, methyl jasmonate, and salicylicacid stresses. Subcellular localization assay confirmedthat LcERF080 is a nuclear protein. LcERF080 overexpressionin Arabidopsis resulted in pleiotropic phenotypeswith a higher seed germination rate and transgenic plantswith enhanced tolerance to salt stress. Further, under stressconditions, the transgenic lines exhibited elevated levels ofsoluble sugars and proline as well as relative moisturecontents but a lower malondialdehyde content than incontrol plants. The expression levels of hyperosmoticsalinity response genes COR15A, RD22, and P5CS1 werefound to be elevated in the LcERF080-overexpressingArabidopsis plants compared to the wild-type plants. Theseresults reveal that LcERF080 is involved in the responsesof plants to salt stress.

An investigation on tribological properties of the chemically capped zinc borate(ZB)/MoS2 nanocomposites in oil

Pei-Rong Wu,Yu-Mei Feng,Ting Ge,Ying-Chao Kong,Zhan-Sheng Ma,Zan Liu,Zhi-Lin Cheng 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.63 No.-

The surface of self-made MoS2 nanosheets with five-layer structure was successively decorated by zinc borate (ZB) nanoparticles with coordination enhancement on the tribological performance and modified by three types of modifiers for improving dispersivity in oil. A series of characterizations determined the chemical modification and composite structure of the ZB/MoS2 nanocomposites. The tribological properties of the chemically capped ZB/MoS2 nanocomposites were extensively examined on a ball-on-ball wear tester. The average friction coefficient and average wear scar diameter of the OA-ZB/MoS2-based oil dropped by about 25.2% and 52.2%, and furthermore the extreme pressure performance increased by about 15.2% compared to oil.

A Study On Critical Thinning In Thin-walled Tube Bending Of Al-Alloy 5052O Via Coupled Ductile Fracture Criteria

Heng Li,He Yang,Mei Zhan 한국소성가공학회 2010 기타자료 Vol.2010 No.6

Thin-walled tube bending(TWTB) method of Al-alloy tube has attracted wide applications in aerospace, aviation and automobile,etc. While, under in-plane double tensile stress states at the extrados of bending tube, the overthinning induced ductile fracture is one dominant defect in Al-alloy tube bending. The main objective of this study is to predict the critical wall-thinning of Al-alloy tube bending by coupling two ductile fracture criteria(DFCs) into FE simulation. The DFCs include Continuum Damage Mechanics(CDM)-based model and GTN porous model. Through the uniaxial tensile test of the curved specimen, the basic material properties of the Al-alloy 5052O tube is obtained; via the inverse problem solution, the damage parameters of both the two fracture criteria are interatively determined. Thus the application study of the above DFCs in the TWTB is performed, and the more reasonable one is selected to obtain the critical thinning of Al-alloy tube in bending. The virtual damage initiation and evolution (when and where the ductile fracture occurs) in TWTB are investigated, and the fracture mechanisms of the voided Al-alloy tube in tube bending are consequently discussed.

Antioxidant Flavone Glycosides from the Root of Pteroxygonum giraldii

Li, Bao-Lin,Yang, Zhan-Jun,Jiang, Lin-Ling,Zhang, Xi-Quan,Gu, Hong-Mei,Wang, Hui-Chun,Tian, Xian-Hua Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.7

Two new flavone glycosides, giraldiin A and B, together with three known compounds, annulatin, myricetin 3-O-$\alpha$- L-rhamnopyranoside and gallic acid, were isolated from the ethanol extract of the root of Pteroxygonum giraldii Damm. et Diels. The structures of giraldiin A and B are designated as 3'-($\alpha$-L-arabinopyranosyloxy)-4',5,5',7- tetrahydroxy-3-methoxyflavone and 4'-($\beta$-D-glucopyranosyloxy)-5,5',7-trihydroxy-2',3-dimethoxyflavone, respectively, on the basis of detailed spectroscopic analyses. The free radical scavenging activity of giraldiin A was evaluated by decolouring spectrophotometry of pentamethine cyanine dye (Cy5) with $Fe^{2+}-H_2O_2$ Fenton radical generating system. The results indicated the hydroxyl free radical scavenging activity of giraldiin A (E$D_{50}$ = 23.7 nmol/mL) is higher than that of some known antioxidants such as rutin, puerarin, daidzein and 2,6-di-tertbutyl-4-methylphenol.

Efficiency Optimization Control of an IPMSM Drive System for Electric Vehicles (EVs)

Qin-Mu Wu,Yu Zhan,Mei Zhang,Xiang-Ping Chen,Wen-Ping Cao 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.8

Electric vehicles are a key technology to decarbonize the transport sector where interior permanent magnet synchronous motors (IPMSMs) are the best performer at the heart of the electrical drive system. In order to optimize their operational efficiency, the model-based method associated with parameter identification is widely adopted. However, efficiency optimization and parameter identification in the existing methods are implemented independently by different strategies in a sequential execution manner, which does not produce an optimized systemlevel solution. In this paper, the two methods are combined to deal with a constrained optimization problem in an IPMSM drive. Firstly, the problem is converted into a variational problem based on the variational principle and projection dynamic theory. Then, a unified projection dynamic equation (UPDE) is used to estimate the parameters and determine the solution of optimal current (OC) of the IPMSM. Further, a recursive neural network (RNN)corresponding to the UPDE is developed to implement the developed fast efficiency optimization of the IPMSM drive. The results of simulation experiments show the proposed method is effective to identify motor parameters and determine the OC of the drive system rapidly and accurately. Thus, it can rapidly realize efficiency optimization of an IPMSM drive-system. Because the designed RNN can be easily implemented in the hardware, such as a field-programmable gate array (FPGA) or dedicated neural network chip, the method can achieve instantaneousefficiency optimization of the IPMSM drive system and therefore improve the widespread application of IPMSMs in EVs.

Density-based Outlier Detection in Multi-dimensional Datasets

Xite Wang,Zhixin Cao,Rongjuan Zhan,Mei Bai,Qian Ma,Guanyu Li 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.12

Density-based outlier detection is one of the hot issues in data mining. A point is determined as outlier on basis of the density of points near them. The existing density-based detection algorithms have high time complexity, in order to reduce the time complexity, a new outlier detection algorithm DODMD (Density-based Outlier Detection in Multidimensional Datasets) is proposed. Firstly, on the basis of ZH-tree, the concept of micro-cluster is introduced. Each leaf node is regarded as a micro-cluster, and the micro-cluster is calculated to achieve the purpose of batch filtering. In order to obtain n sets of approximate outliers quickly, a greedy method is used to calculate the boundary of LOF and mark the minimum value as LOF i . Secondly, the outliers can filtered out by LOF i , the real outliers are calculated, and then the result set is updated to make the boundary closer. Finally, the accuracy and efficiency of DODMD algorithm are verified on real dataset and synthetic dataset respectively.

Biotransformation, a Promising Technology for Anti-cancer Drug Development

Gao, Fei,Zhang, Jin-Ming,Wang, Zhan-Guo,Peng, Wei,Hu, Hui-Ling,Fu, Chao-Mei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

With the high morbidity and mortality caused by cancer, finding new and more effective anti-cancer drugs is very urgent. In current research, biotransformation plays a vital role in the research and development of cancer drugs and has obtained some achievements. In this review, we have summarized four applications as follows: to exploit novel anti-cancer drugs, to improve existing anti-cancer drugs, to broaden limited anti-cancer drug resources and to investigate correlative mechanisms. Three different groups of important anti-cancer compounds were assessed to clarify the current practical applications of biotransformation in the development of anti-cancer drugs.

A Genetic Linkage Map Construction for Sesame (Sesamum indicum L.)

Li Bin Wei,Hai Yang Zhang,Yong Zhan Zheng,Hong Mei Miao,Tian Zhen Zhang,Wang Zhen Guo 한국유전학회 2009 Genes & Genomics Vol.31 No.2

Sesame (Sesamum indicum L.) is one of the oldest oilseed crops with high seed oil quality. The first sesame genetic linkage map based on F2 segregating population of an intraspecific cross between two cultivars was constructed. Using three types of PCR-based markers, 284 polymorphic loci including 10 EST-SSR marker, 30 AFLP marker and 244 RSAMPL marker, respectively, had been screened. Subsequently, a total of 220 molecular markers were mapped in 30 linkage groups covering a genetic length of 936.72 cM, and the average distance between markers was 4.93 cM. In this map, the linkage groups contained from 2 to 33 loci each and ranged in distance from 6.44 cM to 74.52 cM. Based on map information, sesame genome length was estimated to be approximately 1,232.53 cM, and genome coverage of this map was about 76.0%. As a starting point of sesame genome study, the genetic linkage map will be hopeful to tag traits of breeding interest and further aid in the sesame molecular breeding. Furthermore, RSAMPL marker had been also appreciated in this paper, for its first usage in genetic map construction and higher utilization potential in some crop species lacking much genome information.

Tissue distribution and functional characterization of odorant binding proteins in Chilo suppressalis (Lepidoptera: Pyralidae)

Sajjad Ali Khuhro,Hui Liao,Guan-Heng Zhu,Shuang-Mei Li,Zhan-Feng Ye,Shuang-Lin Dong 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

Odorant binding proteins (OBPs) play important roles in the insect olfaction and other diverse physiological processes. Forty OBP genes have been molecularly identified from Chilo suppressalis (Walker), a notorious rice pest in Asian countries, but little is known about the olfactory function for most of these genes. In the present study, we first determined the tissue expression profiles of 34 OBPs (excluding two general odorant bonding proteins (GOBPs) and four pheromone binding protein (PBPs)) by quantitative real-time PCR (qPCR), and found that 9 genes (OBP1, 3, 4, 11, 15, 17, 19, 20 and 24) were specifically or predominantly expressed in antennae of both sexes, suggesting their roles in olfaction, while three genes (OBP29, 30 and 32) were almost not expressed in antennae. Focusing on olfactory roles, the ligand specificities of six antenna specifically or predominantly expressed genes were further investigated for 35 plant volatiles, using the fluorescence competitive binding assays. The results revealed that six OBPs displayed different ligand preference, suggesting a differentiation of OBPs in ligand binding spectrum. Of six tested OBPs, OBP3, 11, 17, 19 and 31 showed moderate (Ki =10.21–19.85 μM) or high (Ki < 10.00 μM) binding affinity for 11 and one plant volatiles, respectively. In particular, a plant volatile β-ionone had high or moderate binding to all five OBPs. Our study suggests that these five OBP genes play important roles in the perception of different host plant volatiles, providing insight into the olfactory mechanism in C. suppressalis.