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      저자 : Megui Marilia Mansilla Gallegos (검색결과 1 건)
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        Insufflation of Carbon Dioxide versus Air During Colonoscopy Among Pediatric Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

        John Alexander Lata Guacho,Diogo Turiani Hourneaux De Moura,Igor Braga Ribeiro,Bruna Furia Buzetti Hourneaux de Moura,Megui Marilia Mansilla Gallegos,Thomas McCarty,Ricardo Katsuya Toma,Eduardo Guimar 대한소화기내시경학회 2021 Clinical Endoscopy Vol.54 No.2

        Background/Aims: Carbon dioxide is increasingly used in insufflation during colonoscopy in adult patients; however, air insufflationremains the primary practice among pediatric gastroenterologists. This systematic review and meta-analysis aims to evaluateinsufflation using CO2 versus air in colonoscopies in pediatric patients. Methods: Individualized search strategies were performed using MEDLINE, Cochrane Library, EMBASE, and LILACS databasesfollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and Cochrane workingmethodology. Randomized control trials (RCTs) were selected for the present meta-analysis. Pooled proportions were calculated foroutcomes including procedure time and abdominal pain immediately and 24 hours post-procedure. Results: The initial search yielded 644 records, of which five RCTs with a total of 358 patients (CO2: n=178 versus air: n=180) wereincluded in the final analysis. The procedure time was not different between the CO2 and air insufflation groups (mean difference,10.84; 95% confidence interval [CI], -2.55 to 24.22; p=0.11). Abdominal pain immediately post-procedure was significantly lowerin the CO2 group (risk difference [RD], -0.15; 95% CI; -0.26 to -0.03; p=0.01) while abdominal pain at 24 hours post-procedure wassimilar (RD, -0.05; 95% CI; -0.11 to 0.01; p=0.11). Conclusions: Based on this systematic review and meta-analysis of RCT data, CO2 insufflation reduced abdominal pain immediatelyfollowing the procedure, while pain was similar at 24 hours post-procedure. These results suggest that CO2 is a preferred insufflationtechnique when performing colonoscopy in pediatric patients.

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